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  1. 1042241
    “…These methods have been used previously for classification or discrimination of AD in subjects in a prodromal stage called stable MCI (MCIs), which does not convert to AD but remains stable over a period of time, and converting MCI (MCIc), which converts to AD, but the results reported across similar studies are often inconsistent. …”
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    Classification and Graphical Analysis of Alzheimer’s Disease and Its Prodromal Stage Using Multimodal Features From Structural, Diffusion, and Functional Neuroimaging Data and the APOE Genotype
  2. 1042242
    por Nazzal, Ehab
    Publicado 2020
    “…We hypothesized that prescribing a lower strength opioid tablet would not adversely influence post-operative pain or increase opioid consumption METHODS: All data was collected prospectively from patients undergoing ACL reconstruction at a single academic ambulatory surgery center.All patients received the same peri-operative pain management protocol, which consisted of an adductor canal block at the time of surgery, Naprosyn 500 mg to be taken as needed, and pre-operative opioid education that outlined safe opioid use practice. …”
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    Characterizing the Effect of Opioid Tablet Strength on Post-Operative Opioid Consumption Following ACL Reconstruction
  3. 1042243
    “…There was no difference in the rate of graft rupture between cohorts (BTB 10.0% vs HS 15.2%, p = 0.45). Mean time to graft rupture was 21 months (range 8 – 35 months) and Kaplan-Meier survival curves demonstrated no difference between cohorts. …”
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    Graft Choice for Adolescent Athletes Returning to High-Risk Sports: A Matched Cohort Analysis of Patellar Tendon and Hamstring Autografts
  4. 1042244
    “…METHODS: After IRB approval (IRB# 2018-0490), samples of non-injured hamstring tendon were obtained from 9 patients at the time of surgery (Fig 1 and Table 1). Tenocytes Isolation (Fig 2): Tendons were carefully dissected to remove adjacent connective tissue, minced into small pieces and digested in collagenase1 and dispase for 1h at 37oC. …”
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    Evaluation of SS-31 as a Potential Therapeutic Target in the Treatment of Tendinopathy
  5. 1042245
    “…Thus, the purpose of this study was to quantitatively measure the stiffness of the scalene muscles using real-time shear wave elastography (SWE). The stiffness of scalene muscles was hypothesized to increase for the throwing side of baseball players. …”
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    Throwing can Increase the Stiffness of the Scalene Muscle
  6. 1042246
    “…Excessive fibrosis is associated with adverse clinical outcomes, but longitudinal human data regarding changes in left ventricular remodelling and fibrosis over time are sparse because of the slow progression, thereby making longitudinal studies challenging. …”
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    Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy
  7. 1042247
    “…There were also no differences between mean surgery time of intraoperative blood loss between the enhanced recovery after surgery and non- enhanced recovery after surgery groups. …”
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    Enhanced recovery after surgery (ERAS) program for elderly patients with short-level lumbar fusion
  8. 1042248
    “…Conclusion: In this exploratory analysis, we showed for the first time that patients with both persistent tumor-associated hypoxia during treatment and PD-L1 expression on tumor cells exhibited a worse outcome, while the tumor cells' PD-L1 expression did not influence the outcomes of patients with early tumor hypoxia resolution. …”
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    Hypoxia dynamics on FMISO-PET in combination with PD-1/PD-L1 expression has an impact on the clinical outcome of patients with Head-and-neck Squamous Cell Carcinoma undergoing Chemoradiation
  9. 1042249
    “…There was also a significant difference in the intervention group over time (P=.008) for HRQL related to treatment problems, with the intervention group participants demonstrating improved HRQL by 12 months compared with education control group participants. …”
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    Teens Taking Charge: A Randomized Controlled Trial of a Web-Based Self-Management Program With Telephone Support for Adolescents With Juvenile Idiopathic Arthritis
  10. 1042250
    por Pereira, Maria Fernanda Badue, Litvinov, Nadia, Farhat, Sylvia Costa Lima, Eisencraft, Adriana Pasmanik, Gibelli, Maria Augusta Bento Cicaroni, de Carvalho, Werther Brunow, Fernandes, Vinicius Rodrigues, Fink, Thais de Toledo, Framil, Juliana Valéria de Souza, Galleti, Karine Vusberg, Fante, Alice Lima, Fonseca, Maria Fernanda Mota, Watanabe, Andreia, de Paula, Camila Sanson Yoshino, Palandri, Giovanna Gavros, Leal, Gabriela Nunes, Diniz, Maria de Fatima Rodrigues, Pinho, João Renato Rebello, Silva, Clovis Artur, Marques, Heloisa Helena de Sousa, Rossi Junior, Alfio, Delgado, Artur Figueiredo, de Andrade, Anarella Penha Meirelles, Schvartsman, Claudio, Sabino, Ester Cerdeira, Rocha, Mussya Cisotto, Kanunfre, Kelly Aparecida, Okay, Thelma Suely, Carneiro-Sampaio, Magda Maria Sales, Jorge, Patricia Palmeira Daenekas
    Publicado 2020
    “…The study group comprised 66/371 (18%) laboratory-confirmed pediatric COVID-19 patients: 61 (92.5%) patients tested positive on real-time reverse transcription-polymerase chain reaction tests for SARS-CoV-2, and 5 (7.5%) patients tested positive on serological tests. …”
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    Severe clinical spectrum with high mortality in pediatric patients with COVID-19 and multisystem inflammatory syndrome
  11. 1042251
    “…Case incidence fell from 195 to 75 cases per 1,000 during phase I (61.5% reduction) and to 67 per 1,000 during phase II (65.6% overall reduction). Interrupted time series (ITS) analysis was used to estimate the level and trend change in malaria cases associated with the set of project interventions and the number of cases averted. …”
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    A multiphase program for malaria elimination in southern Mozambique (the Magude project): A before-after study
  12. 1042252
    “…Medicinal plants have been intensively utilized by humans for a long time to treat various ailments. In spite of their reported efficacies, empirical scientific data supporting their healing claims is scanty. …”
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    Acute Oral Toxicity and Anti-inflammatory and Analgesic Effects of Aqueous and Methanolic Stem Bark Extracts of Piliostigma thonningii (Schumach.)
  13. 1042253
    “…Baseline (pre) and endline (post) household surveys were done in the control and intervention wards to assess the change in malaria prevalence measured by the interaction term of ‘time’ (post vs pre) and arm in a logistic model. …”
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    Effectiveness of the innovative 1,7-malaria reactive community-based testing and response (1, 7-mRCTR) approach on malaria burden reduction in Southeastern Tanzania
  14. 1042254
    “…Physical activity in both groups decreased over time. Sustaining long-term adherence and engagement in this mHealth intervention proved difficult; approximately two-thirds of the trial’s 357 participants failed to sync their Fitbit device at 12 months and, thus, were lost to follow-up. …”
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    Effect of Adding Telephone-Based Brief Coaching to an mHealth App (Stay Strong) for Promoting Physical Activity Among Veterans: Randomized Controlled Trial
  15. 1042255
    “…Changes to clinical practice, professional remits and research priorities are of indeterminant duration at this time, and some components could be permanent. Significant clinical practice, workforce and research opportunities may exist in the post‐COVID era.…”
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    COVID‐19 and ENT SLT services, workforce and research in the UK: A discussion paper
  16. 1042256
    “…To demonstrate how to address these problems, we have developed the open-source Oral Health and Disease Ontology (OHD) and our instance-based representation as a framework for dental and medical health care information. We envision a time when medical record systems use a common data back end that would make interoperating trivial and obviate the need for a dedicated messaging framework to move data between systems. …”
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    Structuring, reuse and analysis of electronic dental data using the Oral Health and Disease Ontology
  17. 1042257
    “…In vitro, Transwell co-culture system was taken to investigate the role of miR-195 on neuronal-microglial communication through CX3CL1-CX3CR1 signaling. Quantitative real-time PCR was used to detect the level of miR-195 and inflammatory factors. …”
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    MicroRNA-195 prevents hippocampal microglial/macrophage polarization towards the M1 phenotype induced by chronic brain hypoperfusion through regulating CX3CL1/CX3CR1 signaling
  18. 1042258
    “…CONCLUSIONS: The use of an mHealth solution to disseminate time-sensitive medical knowledge seemed to be an effective solution to increase the reach of validated content to a targeted audience.…”
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    Using mHealth to Increase the Reach of Local Guidance to Health Professionals as Part of an Institutional Response Plan to the COVID-19 Outbreak: Usage Analysis Study
  19. 1042259
    “…CONCLUSION: Our simulation-based prognosis of the health care capacities needed helps the management of the hospital and the civil protection service to make reasonable decisions and adapt the disaster response to the realistic needs. At the same time the forecasts create the possibility to plan the strategic response days and weeks in advance. …”
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    Bettenkapazitätssteuerung in Zeiten der COVID-19-Pandemie: Eine simulationsbasierte Prognose der Normal- und Intensivstationsbetten anhand der deskriptiven Daten des Universitätsklinikums Augsburg
  20. 1042260
    “…Demographic data, laboratory tests, and clinical status were recorded from the day of admission until death or discharge, with a minimum follow-up time of 28 days. We defined COV-HI as a C-reactive protein concentration greater than 150 mg/L or doubling within 24 h from greater than 50 mg/L, or a ferritin concentration greater than 1500 μg/L. …”
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    COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study
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