“…INTERPRETATION: Despite some improvements in asthma outcomes over time, the findings from this report indicate that disparities in asthma indicators persist by demographic characteristics, poverty level, and geographic location. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Strengthening the WTC Health Program health informatics infrastructure is warranted for timely programmatic and research decision-making.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The hexalacunary anion [H(2)P(V)(2)W(VI)(12)O(48)](12−) undergoes time-dependent hydrolysis resulting in a mixture of [H(2)P(V)(2)W(VI)(12)O(48)](12−), [P(V)(8)W(VI)(48)O(184)](40−), [P(V)(2)W(VI)(19)O(69)(H(2)O)](14−) and [α(2)-P(V)(2)W(VI)(17)O(61)](10−) which together leads to comparable inhibitory activity (K(i) = 7.5 mM) after 48 h. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Harnessing this technology would support early interventions to limit presymptomatic spread of viral respiratory infections, which is timely in the era of COVID-19.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Out of 31 patients, 10 received an additional (18)F-FDG scan within a median time interval of 12.5 days (range 1–76). Tracer uptake was quantified by standardized uptake values (SUV)max and (SUV)mean, and tumor-to-background ratio (TBR) was calculated (SUVmax tumor/ SUVmean organ). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection detected in positive testing of a nasopharyngeal sample and confirmed by real time reverse-transcriptase polymerase chain reaction (rt-PCR). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Of MMSE domains, orientation to time (HR: 2.00; 95% CI: 1.29–3.11), attention and calculation (HR: 1.49; 95% CI: 1.16–1.92), recall (HR: 2.59; 95% CI: 1.22–5.47), and language (HR: 1.68; 95% CI: 1.25–2.26) were significantly associated with all-cause mortality in the unadjusted model; for one increase in the number of impaired MMSE domains, the unadjusted HR (95% CI) of mortality is 1.51 (1.38, 1.65), and the HR (95% CI) of mortality is 1.12 (1.01, 1.25) with full adjustment; compared to 0 and 1 impaired MMSE domains, the HRs of all-cause mortality associated with 2, 3, 4, and ≥ 5 impaired MMSE domains were 1.14 (95% CI: 0.84–1.54), 1.50 (95% CI: 0.98–2.28), 2.14 (95% CI: 1.12–4.09) and 2.29 (95% CI: 1.24–5.04), respectively, and a dose-dependent relationship was significant (p for trend =0.003). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this model, rodents spontaneously limit food intake and start performing increased physical activity on a running wheel, a result of the imposition of a fixed time schedule for food delivery. In this review, we provide a detailed summary of the experimental research conducted using the ABA model, which includes extended evidence for changes in the anatomy and function of the brain of ABA rodents. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: When MitoTracker Deep Red-labeled high-metastatic Lewis lung carcinoma A11 cells carrying the ND6 G13997A mtDNA mutation were cocultured with CellLight mitochondria-GFP-labeled low-metastatic P29 cells harboring wild-type mtDNA, bidirectional transfer of red- and green-colored vesicles, probably mitochondria-related EVs, was observed in a time-dependent manner. Similarly, intercellular transfer of mitochondria-related EVs occurred between A11 cells and α-smooth muscle actin (α-SMA)-positive cancer-associated fibroblasts (CAFs, WA-mFib), macrophages (RAW264.7) and cytotoxic T cells (CTLL-2). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patients were stratified according to date of injury into 1 distinct time period: 1) March 13 to August 13, 2019 (i.e., before the COVID-19 pandemic, BC19) or 2) March 13 to August 13, 2020 (i.e., during initial 6 months of the COVID-19 pandemic, C19) (Figure 1). …”
Enlace del recurso
Enlace del recurso

“…Furthermore, logistic regression analyses identified treatment time and TSAT as major factors influencing the attainment of adequacy and anemia treatment targets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Western blot and real-time fluorescent quantitative PCR were used to detect the expressions of specific genes and proteins in the brain tissue. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Hence, we investigated the basic growth parameters of HCoV-OC43 infection in three of these cell lines (HRT-18, human lung fibroblasts (MRC-5) and African green monkey kidney (Vero E6) cells) including the differential development of cytopathic effect (CPE) and explored reducing the cost, time and complexity of antibody-based detection assay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Japan has the unique feature that approximately 50% of the survey respondents rated their self-rated health as fair, but with important variations over time and between socioeconomic groups. In-depth studies of the role of socioeconomic conditions may shed light on the reasons for the high prevalence of poor self-rated health in Japan. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Spearman’s correlation coefficient shows that the serum 14-3-3β level was positively correlated with FeNO (r = − 0.292, P = 0.032) and peripheral blood eosinophil count (r = 0.328, P = 0.016), and was negatively related to FEV1/FVC (r = − 0.293, P = 0.031) in the acute exacerbation group of asthma. At the same time, the serum 14-3-3β level was also negatively associated with FEV1 (r = − 0.297, P = 0.036) in the chronic persistent group of asthma. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In children who were retested, the median time of a positive PCR result was 16 days (range 1–70 days), but 12.7% of patients were positive beyond day + 20. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Global response assessment was possible in 40 patients. 17.1% (n=7) had an overall response (CR=1; PR=6), 43.9% (n=18) stable disease and 39% (n=16) progressive disease. The mean (±SEM) time to disease progression was 13.82 (±1.22) months and the median (IQR) mSWAT score increased from 7.25 (0.85–30.25) to 26.4 (2.6–41.78), p=0.08. 12 patients had missed/delayed treatments (phototherapy, n=5; radiotherapy, n=1; topical skin direct therapy, n=3; extracorporeal photopheresis, n=1; investigational medicinal product, n=2). …”
Enlace del recurso
Enlace del recurso

“…Secondary endpoints included time to intervention for central nervous system (CNS) disease, objective response rate, duration of response (DoR), clinical benefit rate, and safety. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Chi-square tests were used to assess differences between medical students and medical professionals, and Pearson’s bivariate correlations were used to analyze associations between survey responses and year of publication—as a proxy measurement to assess change over time. RESULTS: Out of the 741 items retrieved, 40 studies published between 1971 and 2019 were included in the final analyses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: The study included eight GSD-Ia and one GSD-Ib children with a median age of 9.0 (range 4.2–15.7) years at the time of LT. Using propensity score matching, 20 children with biliary atresia (BA) receiving LT were selected as the control group by matching for age, sex, pre-operative serum creatinine (SCr) and pediatric end-stage liver disease (PELD) score. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso