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1043081por Miller, Victoria, Reedy, Julia, Cudhea, Frederick, Zhang, Jianyi, Shi, Peilin, Erndt-Marino, Josh, Coates, Jennifer, Micha, Renata, Webb, Patrick, Mozaffarian, Dariush“…We used Bayesian hierarchical models to account for differences in survey methods and representativeness, time trends, and input data and modelling uncertainty, with five-fold cross-validation. …”
Publicado 2022
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1043082por Gao, Xuejin, Liu, Yuxiu, Zhang, Li, Zhou, Da, Tian, Feng, Gao, Tingting, Tian, Hao, Hu, Hao, Gong, Fangyou, Guo, Dong, Zhou, Junde, Gu, Yingchao, Lian, Bo, Xue, Zhigang, Jia, Zhenyi, Chen, Zhida, Wang, Yong, Jin, Gang, Wang, Kunhua, Zhou, Yanbing, Chi, Qiang, Yang, Hua, Li, Mengbin, Yu, Jianchun, Qin, Huanlong, Tang, Yun, Wu, Xiaoting, Li, Guoli, Li, Ning, Li, Jieshou, Pichard, Claude, Wang, Xinying“…IMPORTANCE: The effect of and optimal timing for initiating supplemental parenteral nutrition (SPN) remain unclear after major abdominal surgery for patients in whom energy targets cannot be met by enteral nutrition (EN) alone. …”
Publicado 2022
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1043083por Bryant, Richard A., Bawaneh, Ahmad, Awwad, Manar, Al-Hayek, Hadeel, Giardinelli, Luana, Whitney, Claire, Jordans, Mark J. D., Cuijpers, Pim, Sijbrandij, Marit, Ventevogel, Peter, Dawson, Katie, Akhtar, Aemal“…Primary outcomes were scores on the Hopkins Symptom Checklist-25 (HSCL; depression and anxiety scales) assessed at baseline, 6 weeks, and 3 months follow-up as the primary outcome time point. It was hypothesized that gPM+ would result in greater reductions of scores on the HSCL than EUC. …”
Publicado 2022
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1043084por Yongguang, Gao, Yibing, Shi, Ping, Xia, Jinyao, Zhang, Yufei, Fu, Yayong, Huang, Yuanshun, Xu, Gutao, Li“…However, noninvasive imaging examination that can both observe the above two methods at the same time has not yet been elucidated. OBJECTIVE: To investigate the diagnostic efficacy of CCTA and computed tomography-derived fractional flow reserve (CT-FFR) based on different risk factors for myocardial ischemia. …”
Publicado 2022
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1043085por Jírů-Hillmann, Steffi, Gabriel, Katharina M. A., Schuler, Michael, Wiedmann, Silke, Mühler, Johannes, Dötter, Klaus, Soda, Hassan, Rascher, Alexandra, Benesch, Sonka, Kraft, Peter, Pfau, Mathias, Stenzel, Joachim, von Nippold, Karin, Benghebrid, Mohamed, Schulte, Kerstin, Meinck, Ralf, Volkmann, Jens, Haeusler, Karl Georg, Heuschmann, Peter U.“…CONCLUSIONS: The majority of caregivers wanted to care for their relatives but experienced burden at the same time. Elderly patients, patients with a lower Barthel Index at discharge and diabetes are at higher risk of needing care by a family caregiver. …”
Publicado 2022
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1043086por Alves, Fátima R, Gil, Lucia, Vasconcelos de Matos, Leonor, Baleiras, Ana, Vasques, Carolina, Neves, Maria Teresa, Ferreira, André, Fontes-Sousa, Mário, Miranda, Helena, Martins, Ana“…Results A total of 72 patients with HER2 BC were included with a median age at diagnosis of 52.5 years and a median follow-up time of 35.5 months. Of patients, 56.9% had HER2-low disease and 43.1% had HER2-0 disease. …”
Publicado 2022
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1043087por Barnett, Lisa M., Webster, E. Kipling, Hulteen, Ryan M., De Meester, An, Valentini, Nadia C., Lenoir, Matthieu, Pesce, Caterina, Getchell, Nancy, Lopes, Vitor P., Robinson, Leah E., Brian, Ali, Rodrigues, Luis P.“…However, to test the whole model, the field needs robust longitudinal studies across childhood and adolescence that include all variables in the model, have multiple time points and account for potential confounding factors. …”
Publicado 2021
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1043088por Zhang, Yu, Li, Saisai, Wang, Ying, Lu, Yang, Xu, Yingxi, Rao, Qing, Wang, Huijun, Xing, Haiyan, Tian, Zheng, Tang, Kejing, Lv, Lulu, Wang, Min, Wang, Jianxiang“…RESULTS: The novel CD22 CAR-T treatment had specific cytotoxicity to CD22 + target cells, and the survival time of mice in the CD22 CAR-T treatment group was significantly prolonged. …”
Publicado 2022
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1043089por Zheng, Chao, Holden, Daniel, Zheng, Ming-Qiang, Pracitto, Richard, Wilcox, Kyle C., Lindemann, Marcel, Felchner, Zachary, Zhang, Li, Tong, Jie, Fowles, Krista, Finnema, Sjoerd J., Nabulsi, Nabeel, Carson, Richard E., Huang, Yiyun, Cai, Zhengxin“…Arterial blood was drawn for the measurement of plasma free fraction (f(P)), radiometabolite analysis, and construction of the plasma input function. Regional time-activity curves (TACs) were fitted with the one-tissue compartment (1TC) model to obtain the volume of distribution (V(T)). …”
Publicado 2021
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1043090“…The functional enrichment and the overall survival time of these potential targeted genes were analyzed, and a PPI network was constructed in the STRING database. …”
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1043091Publicado 2022“…The aim of this study was to explore the proportions of recrudescent parasitaemia as ascribed by genotyping captured at various follow-up time-points in treatment efficacy trials for uncomplicated Plasmodium falciparum malaria. …”
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1043092por Haq, Shiekh Marifatul, Hassan, Musheerul, Jan, Hammad Ahmad, Al-Ghamdi, Abdullah Ahmed, Ahmad, Khalid, Abbasi, Arshad Mehmood“…We also recorded for the first time from this region seven unique food preparations of wild animals. …”
Publicado 2022
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1043093por Hasheminasab, Seyed Sajjad, Conejeros, Iván, D. Velásquez, Zahady, Borggrefe, Tilman, Gärtner, Ulrich, Kamena, Faustin, Taubert, Anja, Hermosilla, Carlos“…Overall, we here describe for the first time the pivotal role of ATP purinergic receptor P2X1 in C. parvum-mediated suicidal NETosis under physioxia (5% O(2)) and its anti-cryptosporidial properties.…”
Publicado 2022
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1043094por Paralkar, Tapasvini Anmol, Lay, Phoebe, Stubbs, Sawyer, Ahmed, Syed Hadi, Ghani, Minha, Osier, Nico“…Screeners spent significantly longer (P=.03) to identify potential participants in March 2020 (55 minutes) than in March 2019 (32 minutes), but spent significantly less time (P=.01) to do so in July 2020 (22 minutes) than in July 2019 (42 minutes). …”
Publicado 2022
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1043095por Ferrari, Giulia, Torres-Rueda, Sergio, Chirwa, Esnat, Gibbs, Andrew, Orangi, Stacey, Barasa, Edwine, Tawiah, Theresa, Dwommoh Prah, Rebecca Kyerewaa, Hitimana, Regis, Daviaud, Emmanuelle, Kapapa, Eleonah, Dunkle, Kristin, Heise, Lori, Stern, Erin, Chatterji, Sangeeta, Omondi, Benjamin, Ogum Alangea, Deda, Karmaliani, Rozina, Maqbool Ahmed Khuwaja, Hussain, Jewkes, Rachel, Watts, Charlotte, Vassall, Anna“…We use a 3% discount rate for investment costs and a 1-year time horizon, assuming no effects post the intervention period. …”
Publicado 2022
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1043096“…Furthermore, a statistically significant time by group interaction effect on pain and disability score was found (interaction p < 0.001). …”
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1043097por Chibwana, Marah G., Moyo-Gwete, Thandeka, Kwatra, Gaurav, Mandolo, Jonathan, Hermanaus, Tandile, Motlou, Thopisang, Mzindle, Nonkululeko, Ayres, Frances, Chaponda, Mphatso, Tembo, Godwin, Mwenechanya, Percy, Mitole, Ndaona, Jassi, Chisomo, Kamng’ona, Raphael, Afran, Louise, Mzinza, David, Mwandumba, Henry C., Gordon, Stephen B., Jere, Khuzwayo, Madhi, Shabir, Moore, Penny L., Heyderman, Robert S., Jambo, Kondwani C.“…Since it is known that antibodies wane with time and new immune-evasive variants are emerging, we aimed to assess the dynamics of anti-Spike antibodies in an African adult population with prior SARS-CoV-2 infection and to determine the effect of subsequent COVID-19 vaccination. …”
Publicado 2022
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1043098por Hoegen, P., Zhang, K. S., Tonndorf-Martini, E., Weykamp, F., Regnery, S., Naumann, P., Lang, K., Ristau, J., Körber, S. A., Dreher, C., Buchele, C., Rippke, C., Renkamp, C. K., Paul, K. M., König, L., Büsch, C., Krisam, J., Sedlaczek, O., Schlemmer, H.-P., Niyazi, M., Corradini, S., Debus, J., Klüter, S., Hörner-Rieber, J.“…Online MR-guided radiotherapy (oMRgRT) is expected to hold potential to improve hepatic SBRT by offering superior soft-tissue contrast for enhanced target identification as well as the benefit of gating and daily real-time adaptive treatment. The MAESTRO trial therefore aims to assess the potential advantages of adaptive, gated MR-guided SBRT compared to conventional SBRT at a standard linac using an ITV (internal target volume) approach. …”
Publicado 2022
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1043099por Mayoral, Karina, Garin, Olatz, Lizano-Barrantes, Catalina, Pont, Angels, Caballero-Rabasco, Araceli M., Praena-Crespo, Manuel, Valdesoiro-Navarrete, Laura, Guerra, María Teresa, Castillo, José Antonio, Mir, Inés de, Tato, Eva, Alonso, Jordi, Serra-Sutton, Vicky, Pardo, Yolanda, Ferrer, Montse“…Reliability and responsiveness subsamples were defined by stability or change in EQ-VAS and the Asthma Control Questionnaire (ACQ), to estimate the intraclass correlation coefficient (ICC) and the magnitude of change over time. RESULTS: The EQ-5D-Y was completed at baseline for 119 children (81 self-responded and 38 through proxy response), with a mean age of 9.1 (1.7) years. …”
Publicado 2022
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1043100por Dettmer, Rabea, Niwolik, Isabell, Cirksena, Karsten, Yoshimoto, Toshiaki, Tang, Yadi, Mehmeti, Ilir, Gurgul-Convey, Ewa, Naujok, Ortwin“…RESULTS: A 24 h exposure of SC-beta cells to proinflammatory cytokines resulted in significant activation of caspase 3/7 and apoptosis via the extrinsic and intrinsic apoptosis signalling pathways. At this time point, SC-beta cells showed a markedly higher sensitivity towards proinflammatory cytokines than non-insulin-producing cells and EndoC-βH1 cells. …”
Publicado 2022
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