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1043521“…Outcome measures included patient-reported (subjective [s]) sleep onset latency (sSOL), wake after sleep onset (sWASO), sleep efficiency (sSE), and total sleep time (sTST). Treatment-emergent adverse events (TEAEs) were assessed. …”
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1043522por Ahmed, Intekhab, Eriksen, Erik, Hofbauer, Lorenz, Khan, Aliya, Le, John, Marcocci, Claudio, Markova, Denka, Pagotto, Uberto, Palermo, Andrea, Pihl, Susanne, Rejnmark, Lars, Schwarz, Peter, Shu, Aimee, Sibley, Christopher, Vansaghi, Lisa, Vokes, Tamara, Clarke, Bart“…In the PD/PK substudy, mean sCa and uCa levels were stable in the normal range at all time points. Active PTH levels reflected steady physiologic exposure throughout the 24-hour period. …”
Publicado 2022
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1043523“…No reported family history of relevant endocrine tumors. At time of initial assessment, functional hormonal baseline workup was normal including ACTH: 23 pg/mL [5-27 pg/mL], AM Cortisol level: 13.6 mcg/dL [4-22 mcg/dL], 24h U-Cortisol: 16.4 mcg/24h/1g Cr [4-50 mcg/24h/1g], and DHEAS: 30 mcg/dL [<185 mcg/dL] Patient was re-evaluated annually. …”
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1043524por Thakkar, Amruta, Redondo, Maria, Hajjar, Joud, Minard, Charles, Huang, Xiaofan, Hwu, Kathy“…Further studies are warranted to investigate potential pathogenic correlates and persistence over time. This knowledge may lead to new targeted strategies to preserve or improve beta-cell function in individuals with clinical or pre-clinical T1D. …”
Publicado 2022
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1043525“…Using flow cytometry, transfection efficiencies were measured in time- and dose-dependent experiments, showing optimal knock-down greater than 95% at 0.5µM for 12 hrs. miR-21 expression measured by qPCR showed a significant decrease within inhibited groups (p=0.0008, n=3). …”
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1043526por Hendrix, Grace, Shankaran, Mahalakshmi, Ramaker, Megan, Evans, William, Hellerstein, Marc, Muehlbauer, Michael, Rasbach, Lisa, Benjamin, Robert, Freemark, Michael, Balikcioglu, Pinar Gumus“…Glycemic control was assessed by glucose time in range, mean blood glucose, and HbA1c. MM was measured using the D(3)creatine dilution method in 22 of the children with T1D (14 females, 8 males) and, in a separate study, in 34 children without T1D (17 females and 17 males). …”
Publicado 2022
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1043527por Ho, Cheuk Wah“…Presentation: No date and time listed…”
Publicado 2022
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1043528por Aulinas, Ana, Muhammed, Maged, Becker, Kendra R, Asanza, Elisa, Hauser, Kristine, Hadaway, Natalie, Misra, Madhusmita, Eddy, Kamryn T, Micali, Nadia, Thomas, Jennifer J, Lawson, Elizabeth A“…Mean oxytocin levels were higher in ARFID compared to HC at all time points (fasting: 1487±94 vs 1268±60 pg/mL, p=0.049; 30 min: 1477±86 vs 1202±48 pg/mL, p=0.006; 60 min: 1473±89 vs 1214±52 pg/mL, p=0.015; 120 min: 1470±102 vs 1253±50 pg/mL, respectively, p=0.056), and AUC (p=0.023). …”
Publicado 2022
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1043529“…Presentation: No date and time listed…”
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1043530“…We chose June 2020 as the pandemic onset since our clinic resumed in-person visits at this time. Demographic and clinical data, including BMI and HbA1c, were collected in the pre-pandemic and pandemic periods for each patient. …”
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1043531por Musurakis, Clio, Marenych, Nadiia, Trendafilova, Victoria, Kircheva, Diana, Gilden, Janice L“…Presentation: No date and time listed…”
Publicado 2022
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1043532por Zenno, Anna, Cohen, Andrea, Babcock, Holly, Moon, Amy, Santhanam, Prasanna, Desai, Jay, Joyal, Elizabeth, Manoli, Irini, Merke, Deborah P“…Presentation: No date and time listed…”
Publicado 2022
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1043533por Mar-Buruato, Ana Marina, Solís-Pérez, Elizabeth, Gonzãlez-Martínez, Blanca Edelia, Lavalle-Gonzãlez, Fernando Javier, Villarreal-Pérez, Jesús Zacarías, Pablo Nuñez-Sãnchez, Juan“…Presentation: No date and time listed…”
Publicado 2022
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1043534por Bando, Hironori, Fukuoka, Hidenori, Iguchi, Genzo, Kanie, Keitaro, Ogawa, Wataru, Shichi, Hiroki, Suzuki, Masaki, Takahashi, Michiko, Takahashi, Yutaka, Urai, Shin, Yamamoto, Naoki, Oi, Yuka, Yamamoto, Masaaki, Sasaki, Yuriko“…Presentation: No date and time listed…”
Publicado 2022
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1043535por Ribeiro-Oliveira, Antonio, O’toole, Dermot, Kunz, Pamela, Houchard, Aude, Boiziau, Sandra, Prebtani, Ally, Webb, Susan“…Pain at injection site occurred with LAN versus OCT 'never' for 13.5% versus 7.1%, 'rarely' for 43.2% versus 37.3%, and 'most of the time' for 27.1% versus 42.9%. CONCLUSIONS: Fewer patients using LAN had injection-site pain lasting >2 days after last injection compared to OCT; thus the primary endpoint was met. …”
Publicado 2022
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1043536“…Presentation: No date and time listed…”
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1043537por Khiyami, Anamil, Fazeli, Pouneh, Mahmud, Hussain, Gardner, Paul, Zenonos, Georgios“…Presentation: No date and time listed…”
Publicado 2022
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1043538por Naik, Vaishali Shashikant“…Presentation: No date and time listed…”
Publicado 2022
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1043539por Abbara, Ali, Bech, Paul, Comninos, Alexander N, Dhillo, Waljit S, Ertl, Natalie, Ettehad, Dena, Goldmeier, David, Howard, Jonathan, Hunjan, Tia, Muzi, Beatrice, Patel, Bijal, Phylactou, Maria, Rabiner, Eugenii A, Suladze, Sofiya, Thurston, Layla, Wall, Matt B, Yang, Lisa, Mills, Edouard G“…CONCLUSION: Collectively, we demonstrate for the first time that kisspeptin administration in men with HSDD increases penile tumescence and psychometric measures of sexual desire and arousal by modulating sexual brain processing. …”
Publicado 2022
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1043540por Bhanot, Sanjay, Fleseriu, Maria, Geary, Richard, Hu, Kuolung, Li, Lu, Melmed, Shlomo, Trunfio, Julia, Waldman, Elaine, Morgan, Erin“…The final analysis included 41 patients in the cimdelirsen low dose (60 and 80 mg; n=22), high dose (120 and 160 mg; n=7) or placebo (n=12) cohorts. 39 of these patients subsequently entered an open label extension (OLE) safety study where all patients were treated with cimdelirsen and at the time of interim analysis, 23 patients were treated for ≥ 1 year (NCT03967249).Patient reported outcomes were assessed using the validated ACROQoL and an acromegaly symptoms questionnaire. …”
Publicado 2022
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