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  1. 1043601
    “…The outcome was good for only two children, while eight children died of neuroblastoma, at a median age of 49.5 months (range = 2.4–174 months), with a median survival time of 21.75 months after diagnosis. CONCLUSIONS: To our knowledge, this represents the first systematic study on the occurrence of NBTs in NF1. …”
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  2. 1043602
    “…Wearing the suit increased thestride time of young subjects (from 1,152 to 1,316 ms, p < 0.001) and was different compared to the older control group (1,172 ms, p = 0.53). …”
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  3. 1043603
    “…To contribute to the understanding of NT1 genetic basis, here we describe, for the first time, a whole genome analysis of a monozygotic twin pair discordant for NT1. …”
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  4. 1043604
    “…The overall good results found for both procedures, as well as the general similarity between outcomes between them, suggest that external considerations like recovery time, comfort level with a more invasive osteotomy, and overall goals with surgery may be of greater importance than short-term clinical outcomes when deciding on the appropriate course of treatment for a given patient.…”
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  5. 1043605
    “…The Hermit reasoner outperforms other reasoners with an average reasoning time of 1.1–2.1 s, under defined settings in our proposed ontology model. …”
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  6. 1043606
    “…Six clinicians participated in one of three focus group interviews; while they reported that the trial and the process of goal setting were acceptable, they raised concerns regarding the additional time required to personalise goals. CONCLUSION: The study protocol and procedures were feasible with acceptable retention of participants. …”
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  7. 1043607
  8. 1043608
    “…RESULTS: The two groups were demographically similar in terms of mean age, BMI and follow-up time (p=.28, p=.84 and p=.06, respectively). Separately, patients from both groups presented significant improvements in all questionnaires (p<.001), except on MCS-12 (fusion p=.08 and non-fusion p=.27). …”
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  9. 1043609
    “…In the adjusted model, we included maternal age, gravidity, and year of birth measured at the time of the index (after interval) births. In a sensitivity analysis, we further adjusted for smoking during pregnancy and prepregnancy body mass index. …”
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  10. 1043610
    “…Currently, positron emission tomography (PET) reporters are not used clinically to visualize altered glutamine metabolism in ccRCC, which greatly hinders detection, staging, and real-time therapeutic assessment. We sought to determine if (2S,4R)-4-[(18)F]fluoroglutamine ([(18)F]FGln) could be used to interrogate altered glutamine metabolism in ccRCC lesions in the lung. …”
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  11. 1043611
    “…However, in a subgroup analysis, we found that the OPG A163G polymorphism increased the risk of osteoporosis in Caucasians (AG + GG vs AA: OR = 1.35, 95% CI = 1.06–1.73; AA + GG vs AG: OR = 0.64, 95% CI = 0.49–0.82) and the female (G vs A: OR = 1.30, 95% CI = 1.03–1.64; AG + GG vs AA: OR = 1.42, 95% CI = 1.18–1.71). At the same time, the OPG G1181C polymorphism reduces the risk of osteoporosis (C vs G: OR = 0.84, 95% CI = 0.74–0.95; CC vs GG: OR = 0.75, 95% CI = 0.60–0.93; GC + CC vs GG: OR = 0.80, 95% CI = 0.67–0.95; CC vs GG + GC: OR = 0.84, 95% CI = 0.70–1.00). …”
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  12. 1043612
    “…The manual cortical thickness measurement methods are time-consuming and require experienced anatomists compared with automated methods. …”
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  13. 1043613
    “…PWI and QoC were significantly different along the type of appointment, with those who held part-time appointments having the least values. The regression models showed that participant’s characteristics such as age, gender, designation, and work volume significantly classified health professionals who had good or poor QoC, QoWL, PW and QoL. …”
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  14. 1043614
  15. 1043615
    “…The pattern of change in blood concentrations with advancing time varied considerably among constituents. However, concentrations of glucose (55.3 and 56.2 mg/dL; SEM = 0.84), lactate (24.1 and 22.5 mg/dL; SEM = 0.79), total protein (7.08 and 7.17 g/dL; SEM = 0.0781), and albumin (2.59 and 2.65 g/dL in wk 2 and 9, respectively; SEM = 0.029) were similar (p > 0.05) between periods one and three. …”
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  16. 1043616
    “…The median limb diameter and procedure time were 27 mm (range:15–48) and 37 min. Overall, clinical success was achieved in 22 cases (88%), with three failures due to AEs (n = 2) or peritoneal carcinomatosis (n = 1). …”
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  17. 1043617
    “…At data cut-off, 188 patients (62.5%) relapsed and the median RFS (mRFS) of the entire population was 18.2 months (95% CI: 15.83–20.57). At the time of analyses 140 patients (46.5%) were alive and the median OS (mOS) was 44.7 months (95% CI: 38.4–51.0). …”
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  18. 1043618
    “…This was accompanied by a greater number of ATTR-CA diagnoses, predominantly of the wild-type nonhereditary form, which is now the most commonly diagnosed form of ATTR-CA (0% versus 54% versus 67% versus 66%, chi-square P<0.001). Over time, the median duration of associated symptoms before diagnosis fell from 36 months between 2002 and 2006 to 12 months between 2017 and 2021 (Mann–Whitney P<0.001), and a greater proportion of patients had early-stage disease at diagnosis across the 5-year periods (National Amyloidosis Centre stage 1: 34% versus 42% versus 44% versus 53%, chi-square P<0.001). …”
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  19. 1043619
    “…Statista. https://www.statista.com/statistics/973815/worldwide-digital-voice-assistant-in-use/ Accessed 17 Jan 2022 Presentation: No date and time listed…”
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  20. 1043620
    “…Significant improvement in “fatigue” was noted in the Yokukansan group (MD = -2.1, 95%CI[-3.4, -0.9], d = 0.47) but not in the placebo group (MD = -0.5, 95%CI[-1.8, 0.8], d = 0.11). The time × group interaction on the improvement in “depression-dejection” was significant (P = .019). …”
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