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1044141por Bashar, Farshid R., Vahedian-Azimi, Amir, Farzanegan, Behrooz, Goharani, Reza, Shojaei, Seyedpouzhia, Hatamian, Sevak, Mosavinasab, Seyed M. M., Khoshfetrat, Masoum, Khatir, Mohammad A. K., Tomdio, Anna, Miller, Andrew C.“…The S(P)O(2)/ F(i)O(2) ratio may allow for early real-time rapid identification of ARDS, while decreasing the cost, phlebotomy, blood loss, pain, skin breaks, and vascular punctures associated with serial arterial blood gas measurements.…”
Publicado 2018
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1044142por Zandstra, H, Smits, L J M, van Kuijk, S M J, van Golde, R J T, Evers, J L H, Dumoulin, J C M, van Montfoort, A P A“…CITO (Dutch Central Institute for Test Development) developed the Dutch pupil monitoring system, which involves nationwide independent, standardized, academic achievement score tests to monitor the child’s school performance twice a year at fixed time points from third grade onward. The tests include language skills (vocabulary and orthography), mathematics and reading capability and comprehension. …”
Publicado 2018
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1044143por Khan, Alisa, Spector, Nancy D, Baird, Jennifer D, Ashland, Michele, Starmer, Amy J, Rosenbluth, Glenn, Garcia, Briana M, Litterer, Katherine P, Rogers, Jayne E, Dalal, Anuj K, Lipsitz, Stuart, Yoon, Catherine S, Zigmont, Katherine R, Guiot, Amy, O’Toole, Jennifer K, Patel, Aarti, Bismilla, Zia, Coffey, Maitreya, Langrish, Kate, Blankenburg, Rebecca L, Destino, Lauren A, Everhart, Jennifer L, Good, Brian P, Kocolas, Irene, Srivastava, Rajendu, Calaman, Sharon, Cray, Sharon, Kuzma, Nicholas, Lewis, Kheyandra, Thompson, E Douglas, Hepps, Jennifer H, Lopreiato, Joseph O, Yu, Clifton E, Haskell, Helen, Kruvand, Elizabeth, Micalizzi, Dale A, Alvarado-Little, Wilma, Dreyer, Benard P, Yin, H Shonna, Subramony, Anupama, Patel, Shilpa J, Sectish, Theodore C, West, Daniel C, Landrigan, Christopher P“…INTERVENTION: Families, nurses, and physicians coproduced an intervention to standardize healthcare provider-family communication on ward rounds (“family centered rounds”), which included structured, high reliability communication on bedside rounds emphasizing health literacy, family engagement, and bidirectional communication; structured, written real-time summaries of rounds; a formal training programme for healthcare providers; and strategies to support teamwork, implementation, and process improvement. …”
Publicado 2018
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1044144por Shrine, Nick, Portelli, Michael A, John, Catherine, Soler Artigas, María, Bennett, Neil, Hall, Robert, Lewis, Jon, Henry, Amanda P, Billington, Charlotte K, Ahmad, Azaz, Packer, Richard J, Shaw, Dominick, Pogson, Zara E K, Fogarty, Andrew, McKeever, Tricia M, Singapuri, Amisha, Heaney, Liam G, Mansur, Adel H, Chaudhuri, Rekha, Thomson, Neil C, Holloway, John W, Lockett, Gabrielle A, Howarth, Peter H, Djukanovic, Ratko, Hankinson, Jenny, Niven, Robert, Simpson, Angela, Chung, Kian Fan, Sterk, Peter J, Blakey, John D, Adcock, Ian M, Hu, Sile, Guo, Yike, Obeidat, Maen, Sin, Don D, van den Berge, Maarten, Nickle, David C, Bossé, Yohan, Tobin, Martin D, Hall, Ian P, Brightling, Christopher E, Wain, Louise V, Sayers, Ian“…We also report for the first time genetic variants associated with the risk of developing moderate-to-severe asthma that regulate mucin production. …”
Publicado 2019
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1044145por Rocha, Rodrigo Silva de Paula, Ribeiro, Igor Braga, de Moura, Diogo Turiani Hourneaux, Bernardo, Wanderley Marques, Minata, Maurício Kazuyoshi, Morita, Flávio Hiroshi Ananias, Aquino, Júlio Cesar Martins, Baba, Elisa Ryoka, Miyajima, Nelson Tomio, de Moura, Eduardo Guimarães Hourneaux“…SPMC demonstrated better tolerability levels when compared to PEG in the following subgroups: “day-before preparation” [MH FE, RD 0.17, IC (0.13, 0.21), P < 0.0001, I(2) = 0%, NNT 6], “preparation in accordance with time interval for colonoscopy” [MH RE, RD 0.08, IC (0.01, 0.15), P = 0.02, I(2) = 54%, NNT 13], when compared to “high-volume PEG solutions” [MH RE, RD 0.08, IC (0.01, 0.14), I(2) = 89%, P = 0.02, NNT 13] and in the subgroup “liquid diet on day before” [MH RE, RD 0.14, IC (0.06,0.22), P = 0.0006, I(2) = 81%, NNT 8]. …”
Publicado 2018
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1044146por D’Almeida, Olga, Mothar, Omar, Bondzie, Esther Apraku, Lieumo, Yolande, Tagne, Laure, Gupta, Sumeet, Volkert, Thomas, Levine, Stuart, Tagne, Jean-Bosco“…Viability and cytotoxicity were determined by cell cycle and quantitative real-time PCR analyses were used to quantify levels of miR-200c and its target genes. …”
Publicado 2019
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1044147por Homsy, Jaco, King, Rachel, Bannink, Femke, Namukwaya, Zikulah, Vittinghof, Eric, Amone, Alexander, Ojok, Francis, Rukundo, Gordon, Amama, Sharon, Etima, Juliane, Matovu, Joyce, Weissglas, Fitti, Ojom, Lawrence, Atim, Pamela, Darbes, Lynae, Byamugisha, Josaphat, Rutherford, George, Katabira, Elly, Fowler, Mary Glenn“…The control group received standard counseling at the time of HIV retesting. Both intervention and control couples were offered couple HIV testing and counseling at all study visits. …”
Publicado 2019
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1044148por van der Houwen, L E E, Lier, M C I, Schreurs, A M F, van Wely, M, Hompes, P G A, Cantineau, A E P, Schats, R, Lambalk, C B, Mijatovic, V“…Secondary outcomes are cumulative live birth rate after one IVF/ICSI treatment cycle (including fresh and frozen embryo transfers up to 15 months after randomization), ongoing pregnancy rate and time to pregnancy. In addition, treatment outcome parameters, adverse events, side-effects during the first 3 months, complications, recurrence of endometriosis (complaints), quality of life, patient preferences, safety and costs effectiveness will be reported. …”
Publicado 2019
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1044149por MANASEKI‐HOLLAND, SEMIRA, LILFORD, RICHARD J., TE, AN P., CHEN, YEN‐FU, GUPTA, KESHAV K., CHILTON, PETER J., HOFER, TIMOTHY P.“…POLICY POINTS: The use of standardized mortality rates (SMRs) to profile hospitals presumes differences in preventable deaths, and at least one health system has suggested measuring preventable death rates of hospitals for comparison across time or in league tables. The influence of reliability on the optimal review number per case note or hospital for such a program has not been explored. …”
Publicado 2019
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1044150por Crowther, Caroline A., Middleton, Philippa F., Voysey, Merryn, Askie, Lisa, Zhang, Sasha, Martlow, Tanya K., Aghajafari, Fariba, Asztalos, Elizabeth V., Brocklehurst, Peter, Dutta, Sourabh, Garite, Thomas J., Guinn, Debra A., Hallman, Mikko, Hardy, Pollyanna, Lee, Men-Jean, Maurel, Kimberley, Mazumder, Premasish, McEvoy, Cindy, Murphy, Kellie E., Peltoniemi, Outi M., Thom, Elizabeth A., Wapner, Ronald J., Doyle, Lex W.“…The treatment effect varied little by reason the woman was considered to be at risk of preterm birth, the number of fetuses in utero, the gestational age when first trial treatment course was given, or the time prior to birth that the last dose was given. …”
Publicado 2019
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1044151por Temple, Beth, Toan, Nguyen Trong, Dai, Vo Thi Trang, Bright, Kathryn, Licciardi, Paul Vincent, Marimla, Rachel Ann, Nguyen, Cattram Duong, Uyen, Doan Y, Balloch, Anne, Huu, Tran Ngoc, Mulholland, Edward Kim“…FINDINGS: Of 1424 infants screened between Sept 30, 2013, and Jan 9, 2015, 1201 were allocated to the six groups: 152 (13%) to group A, 149 (12%) to group B, 250 (21%) to group C, 202 (17%) to group D, 251 (21%) to group E, and 197 (16%) to group F. 237 (95%) participants in group C (PCV10) and 232 (92%) in group E (PCV13) completed the primary vaccination series and had blood draws within the specified window at age 5 months, at which time the proportion of infants with IgG concentrations of at least 0·35 μg/mL did not differ between groups at the 10% level for any serotype (PCV10–PCV13 risk difference −2·1% [95% CI −4·8 to −0·1] for serotype 1; −1·3% [–3·7 to 0·6] for serotype 4; −3·4% [–6·8 to −0·4] for serotype 5; 15·6 [7·2 to 23·7] for serotype 6B; −1·3% [–3·7 to 0·6] for serotype 7F; −1·6% [–5·1 to 1·7] for serotype 9V; 0·0% [–2·7 to 2·9] for serotype 14; −2·1% [–5·3 to 0·9] for serotype 18C; 0·0% [–2·2 to 2·3] for serotype 19F; and −11·6% [–18·2 to −4·9] for serotype 23F). …”
Publicado 2019
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1044152por Antonova-Koch, Yevgeniya, Meister, Stephan, Abraham, Matthew, Luth, Madeline R., Ottilie, Sabine, Lukens, Amanda K., Sakata-Kato, Tomoyo, Vanaerschot, Manu, Owen, Edward, Jado, Juan Carlos, Maher, Steven P., Calla, Jaeson, Plouffe, David, Zhong, Yang, Chen, Kaisheng, Chaumeau, Victor, Conway, Amy J., McNamara, Case W., Ibanez, Maureen, Gagaring, Kerstin, Serrano, Fernando Neria, Eribez, Korina, Taggard, Cullin McLean, Cheung, Andrea L., Lincoln, Christie, Ambachew, Biniam, Rouillier, Melanie, Siegel, Dionicio, Nosten, François, Kyle, Dennis E., Gamo, Francisco-Javier, Zhou, Yingyao, Llinás, Manuel, Fidock, David A., Wirth, Dyann F., Burrows, Jeremy, Campo, Brice, Winzeler, Elizabeth A.“…However, ITNs do not fully shield individuals from malaria, may lose potency with time, and can be bulky and difficult to use. Another concern is that mosquitosmay become resistant to the active insecticides that are used in ITNs and vector control. …”
Publicado 2018
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1044153por Rechberger, Tomasz, Mack, Randall J., McCallum, Stewart W., Du, Wei, Freyer, Alex“…RESULTS: Subjects who received morphine or meloxicam IV had a median time to first perceptible pain relief within 6–8 minutes. …”
Publicado 2019
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1044154por Marigliano, Camila, Arocena, Paula, Riaño Gómez, Juan, Libertun, Carlos, Lux-Lantos, Victoria, Fernandez, Marina“…There was no difference in Kiss-stimulated GnRH release in EDC-exposed cells vs C-exposed cells (Repeated measures Two-way ANOVA: Interaction ns; Main Effect: Time of Kiss exposure: p<0.01, n=7). In GN11 cells, exposure to BP2 inhibited Kiss-induced GnRH gene expression, whereas there was no such effect in cells exposed to BP3 (Relative Expression: C-Basal:1.1±0.02, C-Kiss:1.3±0.1, BP2-Basal:1.2±0.1, BP2-Kiss:1.0±0.1, BP3-Basal:1.0±0.1, BP3-Kiss:1.3±0.1; Repeated measures Two-way ANOVA: Interaction p<0.01, n=8). …”
Publicado 2019
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1044155por Mackey, Dawn C., Lachance, Chantelle C., Wang, Peiwei T., Feldman, Fabio, Laing, Andrew C., Leung, Pet M., Hu, X. Joan, Robinovitch, Stephen N.“…Compliant flooring did not affect rate of serious fall-related injuries (0.362 versus 0.422 per 1,000 bed nights, rate ratio [RR]: 1.04, 95% CI: 0.45 to 2.39, p = 0.925; 0.038 versus 0.053 per fall, RR: 0.81, 95% CI: 0.38 to 1.71, p = 0.560), rate of falls with ≥1 serious fall-related injury (0.276 versus 0.303 per 1,000 bed nights, RR: 0.97, 95% CI: 0.52 to 1.79, p = 0.920), or time to first serious fall-related injury (0.237 versus 0.257, hazard ratio [HR]: 0.92, 95% CI: 0.52 to 1.62, p = 0.760). …”
Publicado 2019
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1044156por Mothe, Beatriz, Manzardo, Christian, Sanchez-Bernabeu, Alvaro, Coll, Pep, Morón-López, Sara, Puertas, Maria C., Rosas-Umbert, Miriam, Cobarsi, Patricia, Escrig, Roser, Perez-Alvarez, Núria, Ruiz, Irene, Rovira, Cristina, Meulbroek, Michael, Crook, Alison, Borthwick, Nicola, Wee, Edmund G., Yang, Hongbing, Miró, Jose M., Dorrell, Lucy, Clotet, Bonaventura, Martinez-Picado, Javier, Brander, Christian, Hanke, Tomáš“…METHODS: BCN01 trial was a phase I, open-label, non-randomized, multicenter study in HIV-1-positive individuals diagnosed and treated during early HIV-1 infection to evaluate two vaccination regimen arms, which differed in the time (8 versus 24 week) between the ChAdV63.HIVconsv prime and MVA.HIVconsv boost vaccinations. …”
Publicado 2019
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1044157por Lebares, Carter C., Guvva, Ekaterina V., Olaru, Maria, Sugrue, Leo P., Staffaroni, Adam M., Delucchi, Kevin L., Kramer, Joel H., Ascher, Nancy L., Harris, Hobart W.“…Mean (SD) circle-cutting time improved more at T2 in the modMBSR arm (−24.08 [63.00] seconds) than in the control arm (−4.22 [112.94] seconds; η(2) = 0.23) and at T3 in the modMBSR arm (−4.83 [77.94] seconds) than in the control arm (11.67 [145.17] seconds; η(2 =) 0.13). …”
Publicado 2019
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1044158Publicado 2019“…FINDINGS: Between Dec 14, 2015, and Sept 12, 2017, 7830 women were enrolled and 7829 were randomly assigned to the DMPA-IM group (n=2609), the copper IUD group (n=2607), or the LNG implant group (n=2613). 7715 (99%) participants were included in the modified intention-to-treat population (2556 in the DMPA-IM group, 2571 in the copper IUD group, and 2588 in the LNG implant group), and women used their assigned method for 9567 (92%) of 10 409 woman-years of follow-up time. 397 HIV infections occurred (incidence 3·81 per 100 woman-years [95% CI 3·45–4·21]): 143 (36%; 4·19 per 100 woman-years [3·54–4·94]) in the DMPA-IM group, 138 (35%: 3·94 per 100 woman-years [3·31–4·66]) in the copper IUD group, and 116 (29%; 3·31 per 100 woman-years [2·74–3·98]) in the LNG implant group. …”
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1044159por Grubic, Tyler J., Sowinski, Ryan J., Nevares, Ben E., Jenkins, Victoria M., Williamson, Susannah L., Reyes, Aimee G., Rasmussen, Christopher, Greenwood, Mike, Murano, Peter S., Earnest, Conrad P., Kreider, Richard B.“…Participants performed 11 resistance-exercises (3 sets of 10 repetitions at 70% of 1RM) followed by agility and sprint conditioning drills for time. Participants donated blood to assess catabolic and inflammatory markers, performed isokinetic strength tests, and rated perceptions of muscle soreness, hypoglycemia before, and following exercise and after 48 h of recovery. …”
Publicado 2019
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1044160“…The expression of p300 in renal tissues and the expression of glucocorticoid receptor (GR) α and β, transforming growth factor (TGF)-β1, and activator protein (AP)-1 after dexamethasone treatment were determined by real-time polymerase chain reaction and Western blotting. …”
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