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  1. 1044521
    “…Rapid and effective separation was achieved in a relatively short time. Therefore, the C(18)-NH(2)-GPTS-SiO(2) stationary phase is promising for practical use with a higher phase ratio, demonstrating superiority for use in reversed-phase pCEC separation, and thus, providing a new strategy and valuable reference for the future application of submicron NPS microspheres.…”
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    高碳含量新型亚微米无孔二氧化硅材料的修饰方法及其在反相加压毛细管电色谱平台上的应用
  2. 1044522
    “…Owing to these advantages of COFs, researchers have attempted to coat one MIP layer on COFs; however, the preparation methods are time-consuming and laborious, and the conditions are harsh. …”
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    共价有机框架分子印迹聚合物复合材料的制备及其用于牛奶中痕量诺氟沙星的选择性富集
  3. 1044523
    “…In addition, the PRiME HLB-based pretreatment process does not require tedious operation processes such as activation, balance, and elution, and thus, the sample pretreatment time is greatly shortened. Under the optimal conditions, the 29 target pesticides showed good linearity in the range of 1.0-200.0 μg/L, with correlation coefficients (R(2)) higher than 0.999. …”
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    基于通过型固相萃取-超高效液相色谱-高分辨质谱同时测定杨梅中29种农药残留
  4. 1044524
    “…The intervention increased cardiorespiratory fitness performance as indicated by longer treadmill time to exhaustion (mean z score: exercise group, 0.54 [95% CI, 0.27-0.82]; control group, 0.13 [95% CI, –0.16 to 0.41]; difference between groups, 0.42 SDs [95% CI, 0.01-0.82]; P = .04), and these changes in fitness mediated some of the effects (small percentage of mediation [approximately 10%-20%]). …”
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    Effects of an Exercise Program on Brain Health Outcomes for Children With Overweight or Obesity: The ActiveBrains Randomized Clinical Trial
  5. 1044525
    “…We restricted our analysis to residents of California who were aged 18–65 years at time of death and died of natural causes. We classified the occupational sector into nine essential sectors; non-essential; or unemployed or without an occupation provided on the death certificate. …”
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    COVID-19 mortality and excess mortality among working-age residents in California, USA, by occupational sector: a longitudinal cohort analysis of mortality surveillance data
  6. 1044526
    “…WHAT IS KNOWN ALREADY: A maternal KD in humans elevates gamete and offspring βOHB exposure during conception and gestation, and in rodents is associated with an increased time to pregnancy, and altered offspring organogenesis, post-natal growth and behaviour, suggesting a developmental programming effect. …”
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    β-hydroxybutyrate reduces blastocyst viability via trophectoderm-mediated metabolic aberrations in mice
  7. 1044527
    “…In addition, we performed pre-planned stratified analyses by mode of delivery (vaginal or caesarean delivery), infant sex, multiplicity (singleton or multiple), timing of birth (term or preterm <37 weeks) and neonatal adverse morbidity (absent or present). …”
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    Attention-deficit hyperactivity disorder in children born to mothers with infertility: a population-based cohort study
  8. 1044528
    “…The population was stratified by CHA(2)DS(2)-VASc risk score; history of stroke, systemic embolism, or transient ischemic attack; and age groups. We calculated time to event, incidence rates, and cumulative incidence for outcomes. …”
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    Risk Levels and Adverse Clinical Outcomes Among Patients With Nonvalvular Atrial Fibrillation Receiving Oral Anticoagulants
  9. 1044529
    “…Moreover, to the best of our knowledge, for the first time this study disaggregates figures and stratifies analyses by HIV infection. …”
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    Burden of malaria in pregnancy among adolescent girls compared to adult women in 5 sub-Saharan African countries: A secondary individual participant data meta-analysis of 2 clinical trials
  10. 1044530
    “…Neurophysiological biomarkers of spinal and brainstem activity (the RIII flexion reflex, the N13 component of somatosensory evoked potentials (SEP) and the R2 component of the blink reflex) will be recorded before and at three distinct time points after administration of three medications known to act on the nociceptive system (lacosamide, pregabalin, tapentadol), and placebo, given as a single oral dose in separate study periods. …”
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    IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity
  11. 1044531
    por Pu, Qian, Zhao, Qianqian, Gao, Dezong
    Publicado 2022
    “…CONCLUSIONS: The local recurrence of Paget’s disease after NSM is uncommon; it may develop at a very early age and have a very long time to recurrence, as in our patient, who presented with recurrence 10 years after primary surgery. …”
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    Local recurrence of mammary Paget’s disease after nipple-sparing mastectomy and implant breast reconstruction: a case report and literature review
  12. 1044532
    “…Participants aged 18 years or older who were receiving invasive mechanical ventilation, but not more than 48 h after intubation at time of first infusion, had a PaO(2)/FiO(2) ratio of 60–200 mm Hg, and a confirmed SARS-CoV-2 infection with any variant in the past 14 days were eligible for this study. …”
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    Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial
  13. 1044533
    “…This study evaluated the long-term effects of control interventions on molecular markers of Plasmodium falciparum drug resistance using parasites obtained from humans and mosquitoes at discrete time points. METHODS: Dried blood spot samples collected in 2012 and 2017 community surveys in Asembo, Kenya were genotyped by Sanger sequencing for markers associated with resistance to SP (Pfdhfr, Pfdhps), CQ, AQ, lumefantrine (Pfcrt, Pfmdr1) and artemisinin (Pfk13). …”
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    Temporal trends in molecular markers of drug resistance in Plasmodium falciparum in human blood and profiles of corresponding resistant markers in mosquito oocysts in Asembo, western Kenya
  14. 1044534
    “…Besides reporting on the full product ranges of CYP725A4 in yeast for the first time, the highest total taxanes of around 361.4 ± 52.4 mg/L including 38.1 ± 8.4 mg/L of T5α-ol was produced herein at a small, 10-mL scale by resting cell assay, where the formation of some novel diterpenoids relied on the prior existence of other diterpenes/diterpenoids as shown by statistical analyses. …”
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    Exploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae
  15. 1044535
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    Systemic Treatments with Tyrosine Kinase Inhibitor and Platinum-Based Chemotherapy in Patients with Unresectable or Metastatic Hepatocholangiocarcinoma
  16. 1044536
    “…For those for whom the CDSS was not used from the first day, mean time to use of CDSS was 8·9 days. Based on the manual review of 1195 randomly selected charts, transition from intravenous to oral therapy was significantly more frequent in the intervention group after adjusting for confounders (154 [76·6%] of 201 vs 187 [87%] of 215, +10·4%; OR 1·9, 95% CI 1·1–3·3). …”
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    Impact of interactive computerised decision support for hospital antibiotic use (COMPASS): an open-label, cluster-randomised trial in three Swiss hospitals
  17. 1044537
    por Mlecnik, Bernhard, Torigoe, Toshihiko, Bindea, Gabriela, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Hirohashi, Yoshihiko, Furuhata, Tomohisa, Takemasa, Ichiro, Patel, Prabhudas, Vora, Hemangini, Shah, Birva, Patel, Jayendrakumar B., Rajvik, Kruti N., Pandya, Shashank J., Shukla, Shilin N., Wang, Yili, Zhang, Guanjun, Yoshino, Takayuki, Taniguchi, Hiroya, Bifulco, Carlo, Lugli, Alessandro, Lee, Jiun-Kae Jack, Zlobec, Inti, Rau, Tilman T., Berger, Martin D., Nagtegaal, Iris D., Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol I., Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia, Bavi, Prashant, Roehrl, Michael H. A., Ohashi, Pamela S., Nguyen, Linh T., Han, SeongJun, MacGregor, Heather L., Hafezi-Bakhtiari, Sara, Wouters, Bradly G., Masucci, Giuseppe V., Andersson, Emilia, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Marliot, Florence, Fredriksen, Tessa, Buttard, Bénédicte, Lafontaine, Lucie, Maby, Pauline, Majdi, Amine, Hijazi, Assia, El Sissy, Carine, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Paustian, Christopher, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, Van de Water, Carlijn, van Lent-van Vliet, Shannon, Knijn, Nikki, Mușină, Ana-Maria, Scripcariu, Dragos-Viorel, Marincola, Francesco M., Ascierto, Paolo A., Fox, Bernard A., Pagès, Franck, Kawakami, Yutaka, Galon, Jérôme
    Publicado 2022
    “…The association of Immunoscore with prognosis was evaluated for time to recurrence (TTR), disease-free survival (DFS), and overall survival (OS). …”
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    Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study
  18. 1044538
    “…Newer azole like isavuconazole which had a low mean MIC in our study, can be considered as a good therapeutic option for the future management of resistant infections. Hence timely management of the patients with an appropriate antifungal agent by performing AFST will help in the reduction of resistance in the future.…”
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    P053 Invasive Mucormycosis (Zygomycosis) -Pre-Covid Era and Covid Era: a retrospective study at a tertiary care centre, chennai
  19. 1044539
    “…RESULTS: Mice vaccinated with rSap2 cloned from C. parapsilosis (Sap2-parapsilosis) showed highest increase in survival time (P = .02) and maximum reduction in organ fungal burden (spleen, kidney, lungs, brain) (P <.05); compared with sham immunized controls. …”
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    P120 Vaccine induced protection by secreted aspartyl proteinase 2 from Candida parapsilosis in Candida tropicalis mediated murine systemic candidiasis: a role of B-cells and antibodies
  20. 1044540
    “…To determine any changes in the cell wall chitin and glucan contents, expression fold changes of chitin synthase (CHS1, CHS2, and CHS3), and glucan synthase genes upon caspofungin treatment were determined using real-time qPCR. These findings were correlated with cell wall chitin and glucan content determined by flowcytometry. …”
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    P017 Echinocandin resistance mechanism in Candida tropicalis and Candida glabrata
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