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  1. 1044781
    “…To enable more certain and generalisable conclusions about these potentially important effects, further research is warranted in real‐world settings, intervening across a wider range of foods ‐ as well as alcohol and tobacco products ‐ and over sustained time periods.…”
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  2. 1044782
    “…That is less than 0.5% of the cropland expansion in M&I for the time period of 2000–2016, when biofuel production increased in the US. …”
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  3. 1044783
  4. 1044784
    “…The reasons for this loss are unknown, but high-dose clonal exhaustion [41, 51, 77, 78] is a reasonable possibility since, regardless of the infectious dose, large amounts of LDV proteins are present in all the lymphoidal tissues at the time of the induction of the CTL response. Furthermore, after exhaustion of CTLs in the periphery, continuous replication of LDV in the thymus [65] assures that the mice become permanently immunologically tolerant with respect to LDV antigen-specific CTLs as a result of negative selection in the thymus. …”
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  5. 1044785
    “…Of these, 45 trials assessed treatment outcomes at five weeks or less after commencement of treatment, and six trials assessed outcomes over a longer time frame. We believe that 24 trials had some form of conflict of interest, such as funding by pharmaceutical companies. …”
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  6. 1044786
  7. 1044787
    “…DISCUSSION: These findings provide evidence for the first time that presynaptic marker protein levels are reduced in schizophrenia in vivo and that antipsychotic drug exposure is unlikely to account for this, consistent with the synaptic dysfunction hypothesis.…”
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  8. 1044788
    “…LNG-IUS users were significantly more likely to continue IUC use and had higher hemoglobin levels over time. The LNG-IUS appears to be a safe contraceptive with regard to HIV disease and may be a highly acceptable option for WLHIV. …”
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  9. 1044789
    “…Furthermore, amount of contrast medium used and time between HSG and conception were compared between the two study groups. …”
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  10. 1044790
    “…RESULTS: To study the fate of inhaled AgNP, healthy adult rats were exposed to 1½-hour intra-tracheal inhalations of pristine (105)Ag-radiolabeled, 20 nm AgNP aerosols (with mean doses across all rats of each exposure group of deposited NP-mass and NP-number being 13.5 ± 3.6 μg, 7.9 ± 3.2•10(11), respectively). At five time-points (0.75 h, 4 h, 24 h, 7d, 28d) post-exposure (p.e.), a complete balance of the [(105)Ag]AgNP fate and its degradation products were quantified in organs, tissues, carcass, lavage and body fluids, including excretions. …”
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  11. 1044791
    “…This has the potential to improve the time to consensus as well as to produce a more representative and precise needs and requirements analysis. …”
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  12. 1044792
    “…Change in 6-minute walking distance; [Time Frame: 3 months] RANDOMISATION: In this study, the central randomization system (IWRS, an interactive network response system based on network) is used to randomise the groups. …”
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  13. 1044793
    por Garassino, Marina Chiara, Whisenant, Jennifer G, Huang, Li-Ching, Trama, Annalisa, Torri, Valter, Agustoni, Francesco, Baena, Javier, Banna, Giuseppe, Berardi, Rossana, Bettini, Anna Cecilia, Bria, Emilio, Brighenti, Matteo, Cadranel, Jacques, De Toma, Alessandro, Chini, Claudio, Cortellini, Alessio, Felip, Enriqueta, Finocchiaro, Giovanna, Garrido, Pilar, Genova, Carlo, Giusti, Raffaele, Gregorc, Vanesa, Grossi, Francesco, Grosso, Federica, Intagliata, Salvatore, La Verde, Nicla, Liu, Stephen V, Mazieres, Julien, Mercadante, Edoardo, Michielin, Olivier, Minuti, Gabriele, Moro-Sibilot, Denis, Pasello, Giulia, Passaro, Antonio, Scotti, Vieri, Solli, Piergiorgio, Stroppa, Elisa, Tiseo, Marcello, Viscardi, Giuseppe, Voltolini, Luca, Wu, Yi-Long, Zai, Silvia, Pancaldi, Vera, Dingemans, Anne-Marie, Van Meerbeeck, Jan, Barlesi, Fabrice, Wakelee, Heather, Peters, Solange, Horn, Leora
    Publicado 2020
    “…FINDINGS: Between March 26 and April 12, 2020, 200 patients with COVID-19 and thoracic cancers from eight countries were identified and included in the TERAVOLT registry; median age was 68·0 years (61·8–75·0) and the majority had an Eastern Cooperative Oncology Group performance status of 0–1 (142 [72%] of 196 patients), were current or former smokers (159 [81%] of 196), had non-small-cell lung cancer (151 [76%] of 200), and were on therapy at the time of COVID-19 diagnosis (147 [74%] of 199), with 112 (57%) of 197 on first-line treatment. 152 (76%) patients were hospitalised and 66 (33%) died. 13 (10%) of 134 patients who met criteria for ICU admission were admitted to ICU; the remaining 121 were hospitalised, but were not admitted to ICU. …”
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  14. 1044794
  15. 1044795
    “…Then isolated PSCs were treated with SQ29548 (10(−4) mol/L) for 2 h, followed by 10(−7) mol/L 8-epi-PGF(2α) for 48 h. Real-time polymerase chain reaction was performed to detect the messenger RNA (mRNA) levels of α-smooth muscle actin (α-SMA) and collagen I. …”
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  16. 1044796
    Publicado 2019
    “…RESULTS: ①The median age of 90 patients was 43 (18–60) years old. The median follow-up time was 42 (3–110) months. ②The 5-year progression-free survival (PFS) for R-CHOP group, dose-intensive chemotherapy group and auto-HSCT group were (33.5±10.7) %, (55.3±10.1) % and (65.8±13.6) % (P=0.012), the 5-year overall survival (OS) were (49.7±9.0) %, (61.6±10.2) % and (78.6±7.8) % (P=0.035), respectively. …”
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  17. 1044797
    “…The findings and insights can contribute to a better understanding of the patterns of underage JUUL use, and help public health officials provide timely education and guidance to minors who have intentions of accessing JUUL. …”
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  18. 1044798
    “…Mutant strains 3.5M and 3.6M exhibited 50 ~ 130% enhancement on growth rate, 4 ~ 9 h reduction on fermentation time to consume glucose, and 20 ~ 63% improvement on ethanol productivity than wild-type ZM4 at pH 3.8. …”
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  19. 1044799
    por Simovic, B., Puisieux, F.
    Publicado 2020
    “…Réalisation de la recherche du SARS-CoV-2 par reverse transcription chain reaction (RT-PCR) COVID-19 avec détection des gènes E et S (Realstar SARS-CoV-2 RT-PCR kit 1.0, Altona) ou avec recherche de SARS-CoV-2-S (Real Time Fluorescent RT-PCR kit for detecting 2019-nCoV-BGI). …”
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  20. 1044800
    “…RESULTS: Among persons 15 years and older who were HIV positive, 84.8% were aware of their HIV positive status, of whom 70.7% were currently on ART, with 87.4% of these estimated to have suppressed viral load at the time of the survey. These estimates varied by sex, age, and geo-location type. …”
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