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  1. 1045121
    por Mori, Daisuke
    Publicado 2022
    “…We conducted the following studies to clarify potential rotator cuff degeneration in elderly OA patients, histologically analyzing the torn edges of ruptured rotator cuff tendons from patients with cuff tear arthropathy (CTA) with a proximal humeral fracture with an intact cuff (control) or en bloc cuff tendon remaining on the greater tuberosity from patients with OA after harvesting such tissues at the time of RSA. Then, we compared the clinical results of elderly patients undergoing total shoulder arthroplasty (TSA) and reversed shoulder arthroplasty (RSA) when these patients reached ≥ 80 years of age. …”
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    Paper 90: Histopathology of Rotator Cuff Tendons in Elderly Patients with Glenohumeral Arthritis without Cuff Tears
  2. 1045122
    “…These results may suggest that the bourgeoning availability of online and virtual therapy resources necessitated by the pandemic may have long-lasting value in supplementing postoperative rehabilitation, especially for those patients with limited access to in-person therapy due to time, distance, financial or insurance constraints. …”
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    Poster 207: Effects of the COVID-19 Pandemic Lockdown on Access to Physical Therapy and Postoperative Sport Testing, Patient Reported Outcomes and Mental Health Scores Following Anterior Cruciate Ligament Reconstruction
  3. 1045123
    “…The marked improvement in ACL mechanics following repetitive training was likely due to the greater ACL loads experienced and the time allowed for tissue recovery. Rodent ligaments can turn collagen over in ˜24 hours(4). …”
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    Poster 254: Mechanical Response of ACL to Submaximal Fatigue Loading
  4. 1045124
    “…Glucose anomalies are time dependent. Emerging new markers represent promising alternatives, such as insulin secretion-sensitivity index-2. …”
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    New Entity—Thalassemic Endocrine Disease: Major Beta-Thalassemia and Endocrine Involvement
  5. 1045125
    “…Furthermore, histone 3 modifications had a discrete time evolution indicating differential immune activation.…”
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    Serum level of total histone 3, H3K4me3, and H3K27ac after non-emergent cardiac surgery suggests the persistence of smoldering inflammation at 3 months in an adult population
  6. 1045126
    “…But China's commercial health insurance companies face financial sustainability problems, limited product ranges and high operating costs. At the same time, the informatization level of China's healthcare industry, and the value of healthcare big data, is increasing. …”
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    The challenge of healthcare big data to China’s commercial health insurance industry: evaluation and recommendations
  7. 1045127
    “…More than 90% of the adverse events were grade 1 (mild) or 2 (moderate) with a typical resolution time of 3 days. No grade 4 adverse events or serious adverse events were reported by study vaccines. …”
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    Immunogenicity, durability, and safety of an mRNA and three platform-based COVID-19 vaccines as a third dose following two doses of CoronaVac in China: A randomised, double-blinded, placebo-controlled, phase 2 trial
  8. 1045128
    “…A surveillance capacity and performance assessment of all 11 SCDC states during 2020–2021 indicated that states differed in the availability of data sources used for SCD surveillance and the time frames for accessing each state data source. …”
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    Surveillance for Sickle Cell Disease — Sickle Cell Data Collection Program, Two States, 2004–2018
  9. 1045129
    “…It was only possible to pool the outcomes drug (other than marijuana) use, marijuana use and alcohol use each at two different time points (one and 3 months follow up). At 1 month follow up the weighted averages varied between zero and 0.05 and at 3 months follow up between −0.17 and 0.07. …”
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    Outreach programs to improve life circumstances and prevent further adverse developmental trajectories of at‐risk youth in OECD countries: A systematic review
  10. 1045130
    “…The virtual PEW allows for increased access for young people that previously struggled to attend face-to-face workshops in a timely fashion. The young people and their families benefit from improving their understanding of their pain and learning new strategies to manage it. …”
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    OA01 An innovative model for chronic pain management at the Evelina
  11. 1045131
    “…Presentation: No date and time listed…”
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    ODP608 Quality of Life and Treatment Satisfaction in Patients with Type 1 Diabetes Experiencing Different Models of Care in Saudi Arabia
  12. 1045132
    “…The benefit appeared to be independent of the phosphoinositide 3-kinase (PI3K)/AKT/phosphatase and tensin homologue (PTEN) pathway alteration status of tumours, as ascertained using assays available at the time. Here, we report updated progression-free survival and overall survival results, and a prespecified examination of the effect of PI3K/AKT/PTEN pathway alterations identified by an expanded genetic testing panel on treatment outcomes. …”
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    Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomarker analysis from a randomised, phase 2 trial
  13. 1045133
    “…LIMITATIONS, REASONS FOR CAUTION: This work covers 13 years; however, those included in the later years have a shorter follow-up time. Although electronic health records have improved data availability, data collection in this cohort remains hampered by the absence of a formal booking visit for women presenting with miscarriage and a national miscarriage database or register. …”
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    Reproductive outcomes following recurrent first-trimester miscarriage: a retrospective cohort study
  14. 1045134
    “…The study population included 11,950 children/adolescents (48.1% female, 67.2% aged between 0 and 11 years) and 145,184 adults (60.2% female, 51.1% aged between 18 and 49 years). The mean follow-up time was 236 days (standard deviation (SD) = 44 days, range = 121 to 339 days) in children/adolescents and 254 days (SD = 36 days, range = 93 to 340 days) in adults. …”
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    Post-COVID-19-associated morbidity in children, adolescents, and adults: A matched cohort study including more than 157,000 individuals with COVID-19 in Germany
  15. 1045135
    “…Between 2003 and 2018, 530 patients were treated nonoperatively for tibial plateau fractures, of which 45 had died at follow-up, 30 were younger than 18 years at the time of injury, and 10 had isolated tibial eminence avulsions, leaving 445 patients for follow-up analysis. …”
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    Functional Outcome After Nonoperative Management of Tibial Plateau Fractures in Skeletally Mature Patients: What Sizes of Gaps and Stepoffs Can be Accepted?
  16. 1045136
    “…FINDINGS: Between Sept 13, 2016, and June 30, 2017, 5387 (92%) of 5857 participants were randomly assigned and received emtricitabine and tenofovir alafenamide (n=2694) or emtricitabine and tenofovir disoproxil fumarate (n=2693). At the time of the primary efficacy analysis (ie, when all participants had completed 48 weeks and 50% had completed 96 weeks) emtricitabine and tenofovir alafenamide was non-inferior to emtricitabine and tenofovir disoproxil fumarate for HIV prevention, as the upper limit of the 95% CI of the IRR, was less than the prespecified non-inferiority margin of 1·62 (IRR 0·47 [95% CI 0·19–1·15]). …”
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    Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial
  17. 1045137
    “…Transcriptomic analysis identified significantly differentially expressed genes in the post- vs pre-influenza samples and differences between the groups over time, mapping to pathways related to TB susceptibility. …”
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    2351. Systemic Influenza Infection Impairs Whole Blood Control of Mycobacteria in a Human Challenge Study
  18. 1045138
    “…This association remained after adjustment for age, oxygen use, and steroid use at the time of BAL in a multivariable Cox model (Figure 3). …”
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    2094. A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients
  19. 1045139
    “…CONCLUSIONS: The creation of the Phone Pal Program as a MSV club required a large time commitment from HMSOM student leaders, faculty mentors, and administrators. …”
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    Medical Student Social Calls to Isolated Older Adults: A Pilot Study
  20. 1045140
    “…Mechanisms should be developed for identifying in real time when a resident physician’s workload is excessive, and processes developed to activate additional providers. …”
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    Implementing the 2009 Institute of Medicine recommendations on resident physician work hours, supervision, and safety
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