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1045221por Lawitschka, Anita, Ronceray, Leila, Bauer, Dorothea, Rittenschober, Michael, Zubarovskaya, Natalia, Geyeregger, Rene, Pickl, Winfried F., Kuzmina, Zoya“…Furthermore, when assessing the correlation between autoantibody positivity and the activity of cGvHD at time of analysis, indicators of aberrant B-cell homeostasis were substantiated by a lower proportion of CD27(+) memory B cells (9.1 vs. 14.9%, respectively; p = 0.028), a higher ratio of class-switched CD27(+)IgD(−)/CD27(+) memory B cells (3.5 vs. 5.1%, respectively; p = 0.013), significantly elevated numbers of CD21(low) B cells (36.8 vs. 11.8 × 10(3) cells/mL, respectively; p = 0.013) and a higher ratio of CD21(low)B cells/CD27(+) memory B cells (2.4 vs. 0.4, respectively; p = 0.034) in the active vs. the no cGvHD group. …”
Publicado 2021
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1045222“…SELECTION CRITERIA: We included cluster‐randomized controlled trials (cRCTs), interrupted time series (ITS), or controlled before‐after studies (CBAs) comparing IRS plus ITNs with ITNs alone. …”
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1045223por Murray, Andrea, Wadsworth, Martha, Kraschnewski, Jennifer, Best, Kathleen, Henry-Harris, Carmen“…When asked how we could improve this event in the future, most attendees shared that they wanted more time and more opportunities to connect. One limitation of the event noted by attendees was that attendees were not able to sign up for the round table discussions themselves but were placed strategically at them by our Steering Committee. …”
Publicado 2020
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1045224“…Computed tomography of neck, thorax, abdomen and pelvis did not reveal any underlying malignancy at the time. The diagnosis of SAE-1-positive dermatomyositis was made and she was treated with high-dose prednisolone (1mg/kg), azathioprine and hydroxychloroquine with good response and dermatomyositis went into remission. …”
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1045225“…Indeed, the GP was crucial in synthesising data from different tertiary referrals and providing the key findings and the history to the rheumatologist which led to her eventual diagnosis and timely management. CASE REPORT - KEY LEARNING POINTS: Whilst Cogan’s syndrome is now a relatively well-recognised albeit rare disease, it remains challenging to diagnose owing to its variable presentation and the lack of diagnostic tests. …”
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1045226“…Etanercept was stopped at this time due to concerns around recent malignancy, with a plan to switch to rituximab. …”
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1045227por Andev, Rajinder Singh, Dubey, Shirish, Brand, Alexander, David, Joel, Luqmani, Raashid“…Serology confirmed triple positive antiphospholipid antibody status and a dsDNA titre of > 400 iU/mL. This was the first-time serology had been undertaken despite a history of three deep vein thrombosis (DVT) episodes and two PE incidents. …”
Publicado 2021
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1045228“…This would be an appropriate time to consider repeat imaging. NICE recommends 12 months of treatment for disseminated TB or spine TB with central nervous system involvement but commonest duration in literature is 18 months for bone TB. …”
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1045229por Dhana, Ashar, Hamada, Yohhei, Kengne, Andre P, Kerkhoff, Andrew D, Rangaka, Molebogeng X, Kredo, Tamara, Baddeley, Annabel, Miller, Cecily, Singh, Satvinder, Hanifa, Yasmeen, Grant, Alison D, Fielding, Katherine, Affolabi, Dissou, Merle, Corinne S, Wachinou, Ablo Prudence, Yoon, Christina, Cattamanchi, Adithya, Hoffmann, Christopher J, Martinson, Neil, Mbu, Eyongetah Tabenyang, Sander, Melissa S, Balcha, Taye T, Skogmar, Sten, Reeve, Byron W P, Theron, Grant, Ndlangalavu, Gcobisa, Modi, Surbhi, Cavanaugh, Joseph, Swindells, Susan, Chaisson, Richard E, Ahmad Khan, Faiz, Howard, Andrea A, Wood, Robin, Thit, Swe Swe, Kyi, Mar Mar, Hanson, Josh, Drain, Paul K, Shapiro, Adrienne E, Kufa, Tendesayi, Churchyard, Gavin, Nguyen, Duc T, Graviss, Edward A, Bjerrum, Stephanie, Johansen, Isik S, Gersh, Jill K, Horne, David J, LaCourse, Sylvia M, Al-Darraji, Haider Abdulrazzaq Abed, Kamarulzaman, Adeeba, Kempker, Russell R, Tukvadze, Nestani, Barr, David A, Meintjes, Graeme, Maartens, Gary“…In this population, a parallel strategy (two tests done at the same time) of W4SS with any chest x-ray abnormality had higher sensitivity (89% [70–97]) and lower specificity (33% [17–54]; n=2670) than W4SS alone; at a tuberculosis prevalence of 5%, this strategy would require 379 more rapid diagnostic tests per 1000 people living with HIV than W4SS but detect 18 more tuberculosis cases. …”
Publicado 2022
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1045230por Alfaro‐Serrano, David, Balantrapu, Tanay, Chaurey, Ritam, Goicoechea, Ana, Verhoogen, Eric“…AUTHORS' CONCLUSIONS: Overall, our results suggest that some interventions led to positive impacts on technology adoption among firms across manufacturing, services, and agriculture sectors, but given the wide variation in the time periods, contexts, and study methodologies, the results are hard to generalize. …”
Publicado 2021
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1045231por Jackson, Sarah, Brown, Jamie, Norris, Emma, Livingstone-Banks, Jonathan, Hayes, Emily, Lindson, Nicola“…We measured smoking cessation at the longest time point, using the most rigorous definition available, on an intention‐to‐treat basis. …”
Publicado 2022
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1045232por Balachandren, Neerujah, Davies, Melanie C, Hall, Jennifer A, Stephenson, Judith M, David, Anna L, Barrett, Geraldine, O’Neill, Helen C, Ploubidis, George B, Yasmin, Ephia, Mavrelos, Dimitrios“…We recruited 3545 women who conceived during the SARS-CoV-2 pandemic who were <13 week’s gestation at the time of recruitment. PARTICIPANTS/MATERIALS, SETTING, METHODS: The COVID-19 Contraception and Pregnancy Study (CAP-COVID) was an on-line survey study collecting longitudinal data from pregnant women in the UK aged 18 years or older. …”
Publicado 2022
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1045233por Munro, Alasdair P S, Feng, Shuo, Janani, Leila, Cornelius, Victoria, Aley, Parvinder K, Babbage, Gavin, Baxter, David, Bula, Marcin, Cathie, Katrina, Chatterjee, Krishna, Dodd, Kate, Enever, Yvanne, Qureshi, Ehsaan, Goodman, Anna L, Green, Christopher A, Harndahl, Linda, Haughney, John, Hicks, Alexander, van der Klaauw, Agatha A, Kanji, Nasir, Libri, Vincenzo, Llewelyn, Martin J, McGregor, Alastair C, Maallah, Mina, Minassian, Angela M, Moore, Patrick, Mughal, Mehmood, Mujadidi, Yama F, Holliday, Kyra, Osanlou, Orod, Osanlou, Rostam, Owens, Daniel R, Pacurar, Mihaela, Palfreeman, Adrian, Pan, Daniel, Rampling, Tommy, Regan, Karen, Saich, Stephen, Bawa, Tanveer, Saralaya, Dinesh, Sharma, Sunil, Sheridan, Ray, Thomson, Emma C, Todd, Shirley, Twelves, Chris, Read, Robert C, Charlton, Sue, Hallis, Bassam, Ramsay, Mary, Andrews, Nick, Lambe, Teresa, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D, Liu, Xinxue, Faust, Saul N“…BACKGROUND: Some high-income countries have deployed fourth doses of COVID-19 vaccines, but the clinical need, effectiveness, timing, and dose of a fourth dose remain uncertain. …”
Publicado 2022
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1045234por Chen, Zhenyu, Yan, Langyun, Li, Keyan, Liao, Xian, Nong, Xiaoyu, Huang, Yuanchun, Tang, Peizhi“…Finally, based on the social network analysis method, the keyword network composed of all high-frequency keywords is analyzed through macro analysis, central analysis and community analysis. At the same time, the state trait anxiety questionnaire was used. …”
Publicado 2022
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1045235por Zhao, Huimin“…So far, the relationship between foreign language anxiety, self-efficacy and foreign language achievement is not clear. At the same time, the relationship between foreign language anxiety and specific factors of self-efficacy remains to be discussed. …”
Publicado 2022
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1045236por Kan, Daxue, Lyu, Lianju, Yao, Wenqing, Ye, Xinya, Zan, Bing, Li, Danyang, Yan, Xiaoya, Huang, Weichiao“…CONCLUSION: China should actively cultivate, encourage and promote entrepreneurship, especially pay attention to the role of emotional labor spirit; At the same time, we should pay more attention to the cultivation of innovation and entrepreneurship. …”
Publicado 2022
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1045237por Diakiw, S M, Hall, J M M, VerMilyea, M D, Amin, J, Aizpurua, J, Giardini, L, Briones, Y G, Lim, A Y X, Dakka, M A, Nguyen, T V, Perugini, D, Perugini, M“…Additional analyses showed that the AI model generalized well to different patient demographics and could also be used for the evaluation of Day 6 embryos and for images taken using multiple time-lapse systems. Results suggested that the AI model could potentially be used to differentiate mosaic embryos based on the level of mosaicism. …”
Publicado 2022
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1045238por O’hara, Kelsey, Mullen, Michael, Oberlohr, Verena, Hambright, Sealy, Huard, Johnny, Duke, Victoria“…Follow-up analysis is needed to determine how the benefits of fisetin adapt over time. Randomized, controlled trials are needed to determine optimum senolytic regimens dependent on patient’s gender, specific cells’ senescent burden, SASP expression, and health condition. …”
Publicado 2022
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1045239por Huard, Johnny, Guo, Ping, Huard, Matthieu, Gao, Xueqin, Narkar, Vihang A., Tashman, Scott, Huard, Johnny, Lu, Aiping“…Future studies will investigate the beneficial effects of ERRγ overexpression in ERRGO mice on muscle atrophy after ACL injury at different time points and determine if muscle-specific activation of ERRγ can mitigate age-related muscle progenitor cells dysfunction and offset the infiltration and activation of FAPs and senescent cells after ACL injury…”
Publicado 2022
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1045240por Manyazewal, Tsegahun, Woldeamanuel, Yimtubezinash, Holland, David P., Fekadu, Abebaw, Marconi, Vincent C.“…The MERM device has an electronic module and a medication container that records adherence, stores medication, emits audible and visual on-board alarms to remind patients to take their medications on time and refill, and enables providers to download the data and monitor adherence. …”
Publicado 2022
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