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  1. 341621
    “…The study provides for clinicians the most practical strategy for diagnosing PFO in the future. However, further trials with a large sample size are required to confirm this finding.…”
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    Diagnosis of Patent Foramen Ovale: The Combination of Contrast Transcranial Doppler, Contrast Transthoracic Echocardiography, and Contrast Transesophageal Echocardiography
  2. 341622
    “…. • By providing quantitative measurements and diagnostic image quality in one rapid MRI scan, qDESS has great potential for application in large-scale clinical trials in knee OA. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00330-019-06542-9) contains supplementary material, which is available to authorized users.…”
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    Time-saving opportunities in knee osteoarthritis: T(2) mapping and structural imaging of the knee using a single 5-min MRI scan
  3. 341623
    “…Predicting the subacute infarct lesion may help clinicians prepare for decompression treatment and aid in patient selection for neuroprotective clinical trials.…”
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    Use of Deep Learning to Predict Final Ischemic Stroke Lesions From Initial Magnetic Resonance Imaging
  4. 341624
    “…Predators interacted with 18% of models during field trials. Nearly all interactions were by mesopredators (57%) and rodents (37%). …”
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    Identification of Factors Affecting Predation Risk for Juvenile Turtles Using 3D Printed Models
  5. 341625
    “…Key findings were: (a) some evidence of targeted intervention trials. Large-scale national programmes were tailored to regional activity and health needs, which may contribute toward addressing inequities. …”
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    Inequities and inequalities in outdoor walking groups: a scoping review
  6. 341626
    “…The most widely used outcome measure in SSc clinical trials is the modified Rodnan skin score (mRSS), which is a semi-quantitative assessment of skin stiffness at seventeen body sites. …”
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    High-throughput quantitative histology in systemic sclerosis skin disease using computer vision
  7. 341627
    “…Objective: We performed a meta-analysis of randomized controlled trials (RCTs) to assess the effect of grape products on lipid profile. …”
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    Impact of Grape Products on Lipid Profile: A Meta-Analysis of Randomized Controlled Studies
  8. 341628
    “…RESULTS: Of 4060 articles, 4 randomized controlled trials were identified with 396 patients included in analysis. …”
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    Is Energy Delivery Guided by Indirect Calorimetry Associated With Improved Clinical Outcomes in Critically Ill Patients? A Systematic Review and Meta-analysis
  9. 341629
    por Braman, Sidney S.
    Publicado 2006
    “…RESULTS: Unfortunately, most previous controlled trials guiding the treatment of acute bronchitis have not vigorously differentiated acute bronchitis and the common cold, and also have not distinguished between an acute exacerbation of chronic bronchitis and acute asthma as a cause of acute cough. …”
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    Chronic Cough Due to Acute Bronchitis: ACCP Evidence-Based Clinical Practice Guidelines
  10. 341630
    “…The role of preemptive antiviral therapy and/or adoptive cell therapy for BKV viremia in HCT should be evaluated in clinical trials. DISCLOSURES: G. Papanicolaou, Chimerix: Consultant, Grant Investigator and Investigator, Consulting fee, Grant recipient and Research grant…”
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    BK Polyoma Virus Nephropathy in Hematopoietic Cell Transplant Recipients with Renal Dysfunction
  11. 341631
    “…METHODS: A sample of 37 participants from the general population trialed a VR mindfulness app in a controlled laboratory setting. …”
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    Understanding How Virtual Reality Can Support Mindfulness Practice: Mixed Methods Study
  12. 341632
    “…This subgroup analysis integrated data from 3 Phase 3 trials (COMPOSE-1, COMPOSE-2, COMPOSE-3) to evaluate the safety and efficacy of naldemedine in patients with renal impairment (RI). …”
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    A Renal Impairment Subgroup Analysis of the Safety and Efficacy of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients with Chronic Non-Cancer Pain Receiving Opioid Therapy
  13. 341633
    “…Designed primers and probes for the realtime RT-PCR universal detection of influenza A(H2) viruses could be used in clinical trials of vaccines against influenza A(H2) and screening for H2 in cases of unsubtypeable influenza A in humans.…”
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    Development of a realtime RT-PCR assay for the rapid detection of influenza A(H2) viruses
  14. 341634
    “…Building on our ongoing efforts to develop MERS-CoV vaccines, promising immunogenicity of MNA-delivered MERS-CoV vaccines, and our experience with MNA fabrication and delivery, including clinical trials, we rapidly designed and produced clinically-translatable MNA SARS-CoV-2 subunit vaccines within 4 weeks of the identification of the SARS-CoV-2 S1 sequence. …”
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    Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
  15. 341635
    por Parris, George E
    Publicado 2004
    “…Currently, an antisense drug targeting Bcl-2 (G3139/Genasense(TM), Genta, Inc.) is in late-stage cancer trials and may be on the market for those indications in months. …”
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    Hypothesis links emergence of chloroquine-resistant malaria and other intracellular pathogens and suggests a new strategy for treatment of diseases caused by intracellular parasites
  16. 341636
    “…METHODS: The time course of fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) in patients with T2DM following ipragliflozin treatment that had been observed in earlier clinical trials was modeled using empirical models combined with the maximum drug effect (E(max)) model and disease progression model. …”
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    Model-based Prediction of the Long-term Glucose-Lowering Effects of Ipragliflozin, a Selective Sodium–Glucose Cotransporter 2 (SGLT2) Inhibitor, in Patients with Type 2 Diabetes Mellitus
  17. 341637
    “…Biologic therapies have demonstrated a positive impact on work-related outcomes in clinical trials but real world data are limited. Therefore, we investigated the prevalence and predictors of work impairment and disability among axSpA patients attending a biologic therapy clinic. …”
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    Amongst patients taking biologic therapies for axial spondyloarthritis, which factors are associated with work non-participation?
  18. 341638
    “…Fimasartan could be a safe option for long-term treatment of essential HTN. ClinicalTrials.gov identifier: NCT02385721.…”
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    Long-Term Safety of a Novel Angiotensin Receptor Blocker, Fimasartan, According to the Absence or Presence of Underlying Liver Disease in Korean Hypertensive Patients: A Prospective, 12-Month, Observational Study
  19. 341639
    “…The primary outcomes were lung function, exercise capacity and health status; (IV) randomized controlled trials. RESULTS: Sixteen articles were included from 2009 to 2018 (n=1,096). …”
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    Effects of Tai Chi training on the physical and mental health status in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
  20. 341640
    “…To apply this method in clinical trials, a paper-administered alternative would be of interest. …”
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    Agreement between the Schedule for the Evaluation of Individual Quality of Life-Direct Weighting (SEIQoL-DW) interview and a paper-administered adaption
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