“…The quality of the included studies was appraised using the Cochrane Collaboration Risk of Bias Tool for randomized controlled trials (RCTs) and the National Institutes of Health—National Heart, Lung, and Blood Institute quality assessment tool for cohort observational studies and for before-after (pre-post) studies with no control group. …”
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“…Our findings indicate that the 7D-CDD regimen might be practical and that it might be valuable to design larger clinical fasting trials for improvement of health strategy-targeting in metabolic disorders.…”
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“…Kawasaki disease shock syndrome (KDSS) was defined by presence of circulatory dysfunction, and macrophage activation syndrome (MAS) by the Paediatric Rheumatology International Trials Organisation criteria. Current or previous infection was sought by reverse-transcriptase quantitative PCR in nasopharyngeal and oropharyngeal swabs, and by serological qualitative test detecting SARS-CoV-2 IgM and IgG, respectively. …”
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“…Femoral anteversion was measured during physical examination. 3D motion capture provided lower extremity kinematics and kinetics during quiet standing and during the loading phase (initial contact to peak knee flexion) of an anticipated 45° side-step cut, with 2-3 trials per limb averaged for analysis. Relationships among imaging, static motion capture, and dynamic motion capture measures were investigated using correlation, and backward stepwise linear regression was used to evaluate potential predictors of average dynamic knee abduction moment. …”
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“…Participants walked along a 10-m walkway, turned, and returned to the starting point at a self-selected pace. During dual-task trials, participants simultaneously answered cognitive questions (spelling backwards, serial 6s or 7s, reciting months backwards) while walking. …”
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“…The in vivo safety of local and intravenous administration of MSCs has been demonstrated in multiple human clinical trials, including studies of acute respiratory distress syndrome (ARDS). …”
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“…The second cluster (5.7%) was characterized by low self-reflectiveness, presence of personalizing bias and an excessive number of trials in the beads task. The third cluster (33.5%) was characterized by average scores in all metacognitive tasks but low scores in the social cognitive tasks. …”
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“…In line with this, active vs. passive trials revealed larger BOLD suppression effects in healthy controls than in patients with schizophrenia in multiple brain areas (e.g., lingual gyrus, middle and superior occipital gyrus, posterior parietal cortex, cerebellum). …”
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“…The high variability in performing sports tasks suggests that multiple trials should be analyzed for a more complete and representative evaluation.…”
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“…During each assessment, three monocular trials were performed in each eye alternatively, with subsequent averaged responses for each eye. …”
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“…Understanding whether these features predict cognitive decline, alone or in combination, is crucial to develop new prognostic measures and enhanced stratification for clinical trials. Here, we studied how baseline assessments of in vivo tau pathology (measured by (18)F-AV-1451 PET), neuroinflammation (measured by (11)C-PK11195 PET) and brain atrophy (derived from structural MRI) predicted longitudinal cognitive changes in patients with Alzheimer’s disease pathology. …”
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“…Measures of swallow physiology obtained from thin liquid trials were compared against published healthy reference data using unpaired t tests, chi-squared tests, and Cohen’s d effect sizes (adjusted p < .008). …”
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“…However, dose–response trials may aid future research to determine if dietary supplementation with isoflavones alleviates fescue toxicosis symptoms and promotes livestock growth and performance.…”
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“…Using a natural large animal model of DCM considered superior to small animal models of immunization‐induced cardiomyopathy, combined with a study design comparable with clinical trials, we believe that our results provide the basis for optimism that treatment with BC 007 might also be effective in human patients with DCM.…”
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“…They provide the foundation for new clinical trials for MS.…”
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“…Most studies were performed in the United States (18/28, 64%) and were randomized controlled trials (21/28, 75%). All participants in the included studies were pregnant at the time of study initiation. …”
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“…INTRODUCTION: Randomized controlled trials (RCTs) have demonstrated the efficacy of dulaglutide in adults with type 2 diabetes mellitus (T2DM), but results may not be generalizable in routine practice. …”
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“…METHODS: A comprehensive search of eight databases (including MEDLINE, EMBASE, and Cochrane library) up to February 2018 was conducted to identify studies (trials, cohorts and qualitative evidence) on direct access services for MSK in primary care settings. …”
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“…Prospective randomized controlled trials are needed to confirm the effect of this combination therapy.…”
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“…METHODS: A systematic search in Medline, PubMed, Science Direct, Cumulative Index to Nursing and Allied Health Literature (CINAHL), the Cochrane Central Register of Controlled Trials, and the Institute of Electrical and Electronics Engineers (IEEE) database was performed to find original studies assessing barriers to ePHR adoption/use in chronic care until the end of 2018. …”
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