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342021por Schoenen, Jean, Timmermans, Gregory, Nonis, Romain, Manise, Maïté, Fumal, Arnaud, Gérard, Pascale“…These results are compared to those published for erenumab in the pivotal randomized placebo-controlled trials and to those reported in several recent real-world studies.…”
Publicado 2021
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342022por Mielgo-Ayuso, Juan, Pietrantonio, Laura, Viribay, Aitor, Calleja-González, Julio, González-Bernal, Jerónimo, Fernández-Lázaro, Diego“…The search included studies where l-C or glycine-propionyl l-Carnitine (GPL-C) supplementation was compared with a placebo in an identical situation and tested its effects on high and/or low–moderate performance. The trials that used the supplementation of l-C together with additional supplements were eliminated. …”
Publicado 2021
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342023por Schlienz, Nicolas J., Scalsky, Ryan, Martin, Erin L., Jackson, Heather, Munson, Joel, Strickland, Justin C., Bonn-Miller, Marcel O., Loflin, Mallory, Vandrey, Ryan“…Although bias related to preexisting beliefs regarding the health benefits of cannabis in this sample should be considered, these findings indicate that clinical trials evaluating the efficacy of defined cannabinoid products for specific health conditions are warranted.…”
Publicado 2021
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342024por Subramanian, Harry, Dey, Rahul, Brim, Waverly Rose, Tillmanns, Niklas, Cassinelli Petersen, Gabriel, Brackett, Alexandria, Mahajan, Amit, Johnson, Michele, Malhotra, Ajay, Aboian, Mariam“…MATERIALS AND METHODS: Four databases were searched by a medical librarian and confirmed by a second librarian for all articles published prior to February 1, 2021: Ovid Embase, Ovid MEDLINE, Cochrane trials (CENTRAL), and Web of Science-Core Collection. …”
Publicado 2021
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342025por Patel, Sneh, Mittal, Rhiya, Felix, Elizabeth R., Sarantopoulos, Konstantinos D., Levitt, Roy C., Galor, Anat“…Patients with a longer follow-up and who tried more therapies experienced more significant relief, suggesting multiple trials were necessary for pain reduction.…”
Publicado 2021
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342026por Jia, Katherine M., Eilerts, Hallie, Edun, Olanrewaju, Lam, Kevin, Howes, Adam, Thomas, Matthew L., Eaton, Jeffrey W.“…Seven studies were among sexually active women using contraceptives enrolled in randomized‐controlled trials, three among adolescent girls and young women (AGYW) and three among cohorts enrolling both men and women. …”
Publicado 2022
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342027por Xu, Xuan, Kawakami, Jessica, Millagaha Gedara, Nuwan Indika, Riviere, Jim E, Meyer, Emma, Wyckoff, Gerald J, Jaberi-Douraki, Majid“…These missing or incomplete features can affect and limit the application of quantitative methods in pharmacovigilance for meta-analyses of data during randomized clinical trials. METHODS: Data from patients with hypertension were retrieved and integrated from the FDA Adverse Event Reporting System; 134 antihypertensive drugs out of 1131 drugs were filtered and then evaluated using the empirical Bayes geometric mean (EBGM) of the posterior distribution to build ADE-drug profiles with an emphasis on the pulmonary ADEs. …”
Publicado 2021
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342028“…We made some clinical trials over the two diseases, and from the result obtained, we hypothesize that the suggested drug may be a novel therapeutic target in treating the multiple squamous cell carcinoma with psoriasis vulgaris.…”
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342029“…Further investigation of larger and methodologically sound trials with longer follow-up periods and appropriate comparison groups is needed.…”
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342030por Winthrop, Kevin L, Tanaka, Yoshiya, Takeuchi, Tsutomu, Kivitz, Alan, Matzkies, Franziska, Genovese, Mark C, Jiang, Deyuan, Chen, Kun, Bartok, Beatrix, Jahreis, Angelika, Besuyen, Robin, Burmester, Gerd R, Gottenberg, Jacques-Eric“…METHODS: Data were integrated from seven trials (NCT01668641, NCT01894516, NCT02889796, NCT02873936, NCT02886728, NCT02065700, NCT03025308). …”
Publicado 2022
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342031por Lin, Fuxin, He, Qiu, Tong, Youliang, Zhao, Mingpei, Ye, Gezhao, Gao, Zhuyu, Huang, Wei, Cai, Lveming, Wang, Fangyu, Fang, Wenhua, Lin, Yuanxiang, Wang, Dengliang, Dai, Linsun, Kang, Dezhi“…Methods: We screened patients from the prospective intracerebral hemorrhage (ICH) registration database (RIS-MIS-ICH, ClinicalTrials.gov Identifier: NCT03862729). The enrolled patients had no brain hernia at admission, with a hematoma volume of more than 20 ml. …”
Publicado 2022
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342032“…The satisfactory results of multicenter clinical trials has led to the recent approval of therapy with KRAS(G12C) inhibitors. …”
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342033por Liu, Peiying, Jiang, Dengrong, Albert, Marilyn, Bauer, Christopher E., Caprihan, Arvind, Gold, Brian T., Greenberg, Steven M., Helmer, Karl G., Jann, Kay, Jicha, Gregory, Rodriguez, Pavel, Satizabal, Claudia L., Seshadri, Sudha, Singh, Herpreet, Thompson, Jeffrey F., Wang, Danny J.J., Lu, Hanzhang“…These results demonstrated good inter-rater, inter-scanner, and test-retest reliability in healthy volunteers, and suggested that CO2-CVR has suitable instrumental properties for use as an imaging biomarker of cerebrovascular function in multi-site and longitudinal observational studies and clinical trials.…”
Publicado 2021
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342034“…DATA SOURCES: MEDLINE, Embase, Cochrane Database for Systematic Reviews, INAHTA HTA database, preprint servers (via Europe PMC), ClinicalTrials.gov, WHO ICTRP from 1 January 2020 to 7 May 2021; NICE Evidence Search, NICE Guidance, FIND Website from 1 January 2020 to 24 May 2021. …”
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342035“…High-quality randomized controlled trials are still needed to confirm the effects of ASCT. …”
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342036por Swindle, Taren, Poosala, Anwesh B, Zeng, Nan, Børsheim, Elisabet, Andres, Aline, Bellows, Laura L“…The search included Ovid MEDLINE(R) and Epub Ahead of Print, In-Process & Other Non-Indexed Citations, and Daily, Ovid EMBASE, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus. …”
Publicado 2022
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342037por Canullo, Luigi, Pesce, Paolo, Antonacci, Donato, Ravidà, Andrea, Galli, Matthew, Khijmatgar, Shahnawaz, Tommasato, Grazia, Sculean, Anton, Del Fabbro, Massimo“…Randomized controlled trials that report ARP procedures using different sealing materials, assessing soft tissue as a primary or secondary outcome, with at least 6-week follow‐up were included. …”
Publicado 2021
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342038por Salem, Hytham S., Vasconcellos, Alexander L., Sax, Oliver C., Doan, Kent C., Provencher, Matthew T., Romeo, Anthony A., Freedman, Kevin B., Frank, Rachel M.“…Large-scale randomized controlled trials or comparative studies are needed to draw stronger conclusions comparing the 2 techniques.…”
Publicado 2022
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342039por Xia, Nan, He, Chang, Li, Yang-An, Gu, Minghui, Chen, Zejian, Wei, Xiupan, Xu, Jiang, Huang, Xiaolin“…Proportions of valid trials, the incidence of SE, AMA incidence of each muscle, and their onset latency and amplitude were involved in analyses. …”
Publicado 2022
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342040“…The a-priori selection criteria included all primary research (observational studies and randomised control trials) whilst excluding (case reports, letters to editors, editorials, commentaries and review articles). …”
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