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  1. 342221
    “…Studies emphasise the importance of balancing technical, financial, safety and clinical requirements for device selection through multidisciplinary involvement (especially clinical engineers and clinicians) in decision-making, and the potential of increasing evidence-based purchasing decisions using approaches such as hospital-based health technology assessments, ergonomics and device ‘user trials’. CONCLUSIONS: We highlight the need for more empirical work that evaluates purchasing approaches or interventions, and greater specificity in study reporting (eg, equipment type, evaluation outcomes) to build the evidence base required to influence policy and practice for medical equipment purchasing. …”
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    Purchasing high-cost medical devices and equipment in hospitals: a systematic review
  2. 342222
    “…ELIGIBILITY CRITERIA: Studies conducted in LMICs on PEs of randomised controlled trials (RCTs) and non-RCTs published between January 2008 and January 2020. …”
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    Process evaluation of complex interventions in non-communicable and neglected tropical diseases in low- and middle-income countries: a scoping review
  3. 342223
    “…DATA SOURCES: MEDLINE, Embase, PsycINFO, CINAHL, Health Technology Assessment, Epub Ahead of Print, In-Process and Other Non-Indexed Citations, Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews was searched from inception to 12 April 2021. …”
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    Systematic review of electronic health records to manage chronic conditions among displaced populations
  4. 342224
    “…Most randomized controlled trials (RCTs) show that GEM-based combination therapy is better than GEM alone, while some RCTs have the opposite conclusion. …”
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    The efficacy and safety of gemcitabine-based combination therapy vs. gemcitabine alone for the treatment of advanced pancreatic cancer: a systematic review and meta-analysis
  5. 342225
    “…However, there is a paucity of prospective data because recently completed trials excluded patients with positive surgical margins. …”
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    Trends in Postoperative Intensity-Modulated Radiation Therapy Use and Its Association With Survival Among Patients With Incompletely Resected Non–Small Cell Lung Cancer
  6. 342226
    “…Evidence suggests the positive impact it can provide on headache management, but the number of randomized control trials and population samples should be increased to support its recommendation. …”
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    Osteopathic Manipulative Treatment and the Management of Headaches: A Scoping Review
  7. 342227
    “…Two independent investigators systematically searched databases and ClinicalTrials.gov to identify relevant studies published up to 31 March 2022. …”
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    Efficacy and safety of recanalization therapy for acute ischemic stroke with COVID-19: A systematic review and meta-analysis
  8. 342228
    “…INTRODUCTION: Registries based on Real-World Data (RWD) are those obtained outside of systematised and randomised clinical trials. They allow the collection of information from a large number of patients and enable the participation of a significant number of professionals. …”
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    Developing a real-world database for oncology: a descriptive analysis of breast cancer in Argentina
  9. 342229
    “…CONCLUSIONS: The results of this study show that the ScanWatch measures HR with a degree of accuracy that is acceptable for general consumer use; however, it would not be suitable in circumstances where more accurate measurements of HR are required, such as in health care or in clinical trials. Overall, the ScanWatch was less accurate at measuring HR during ambulatory activities (eg, walking, gardening, and household activities) compared to more sedentary activities (eg, desk work, eat or drink, and sitting). …”
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    Measurement of Heart Rate Using the Withings ScanWatch Device During Free-living Activities: Validation Study
  10. 342230
    “…We predict triple-homozygous patients (14%) reduce chance of atrophy from 70% to 33% by treating in mornings as opposed to mid-afternoon. Future clinical trials could stratify patients treated at optimal times compared to those scheduled normally. …”
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    Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort
  11. 342231
    “…MATERIALS AND METHODS: Retrospective cross‐sectional study using landmark trials leading to the approval of targeted therapies in NSCLC with actionable mutations. …”
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    Targeted therapy in lung cancer: Are we closing the gap in years of life lost?
  12. 342232
    “…Immunotherapy for ALK-rearranged patients requires further exploration and validation by clinical trials.…”
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    Characteristics of the immune microenvironment and their clinical significance in non-small cell lung cancer patients with ALK-rearranged mutation
  13. 342233
    “…Specifically, the efficacy and safety of adalimumab have been demonstrated in pivotal trials; however, data are needed to understand how clinical results translate into improvements in key aspects of the daily lives of UC patients, such as symptoms, health-related quality of life (HRQoL), and disability. …”
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    Impact of adalimumab on disease burden in moderate-to-severe ulcerative colitis patients: The one-year, real-world UCanADA study
  14. 342234
    “…The study participants were 130 children ((67 boys (age 7.76 ± 0.97 years) and 63 girls (age 7.59 ± 0.91 years)), who performed two randomized trials of the 20mSRT with and without a PGA. Twenty-two predictive equations predicted the VO(2)peak values through the performance of the test with and without a PGA. …”
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    The Multistage 20-m Shuttle Run Test for Predicting VO(2)Peak in 6–9-Year-Old Children: A Comparison with VO(2)Peak Predictive Equations
  15. 342235
    “…A systematic search was conducted in the following databases: PubMed, EMBASE, Google Scholar, OpenGrey, Cochrane library, and ClinicalTrials.gov, and studies between 2009 and 2020 were sought. …”
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    Lymph Node Ratio as a Prognostic Factor in Neck Dissection in Oral Cancer Patients: A Systematic Review and Meta-Analysis
  16. 342236
    “…Given the significance of the limbic system in many disease states including MS, such volumetric analyses can be expanded to studying cognitive and emotional disturbances in larger clinical trials. FreeSurfer ScLimbic pipeline provided an efficient and reliable methodology for examining many of the subcortical structures related to the limbic brain.…”
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    Analysis of the extent of limbic system changes in multiple sclerosis using FreeSurfer and voxel-based morphometry approaches
  17. 342237
    “…To evaluate the effects of C-tDCS on pre- and post-offline trials, each parameter was compared using two-way repeated-measures analysis of variance (ANOVA) with factors of intervention and time. …”
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    Unilateral cathodal transcranial direct current stimulation over the parietal area modulates postural control depending with eyes open and closed
  18. 342238
    “…Conclusion: CHM led to clinically meaningful weight loss without serious adverse events in a real-world setting. Further clinical trials are warranted to validate this result.…”
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    Chinese herbal medicine is associated with higher body weight reduction than liraglutide among the obese population: A real-world comparative cohort study
  19. 342239
    “…METHODS: Female stage I-III breast cancer patients receiving chemotherapy in CANTO (CANcer TOxicity; ClinicalTrials.gov identifier: NCT01993498) were included. …”
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    Dynamics of Long-Term Patient-Reported Quality of Life and Health Behaviors After Adjuvant Breast Cancer Chemotherapy
  20. 342240
    “…IMPORTANCE: The provision of antenatal corticosteroids to pregnant patients at gestational age (GA) 22 6/7 weeks or less remains controversial and lacks support from randomized clinical trials. OBJECTIVE: To compare rates of survival and survival without major morbidities among infants born at GA 22 0/7 to 23 6/7 weeks after exposure to antenatal steroids at 22 6/7 weeks’ gestation or less vs no exposure to antenatal steroids. …”
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    Association of Antenatal Steroid Exposure at 21 to 22 Weeks of Gestation With Neonatal Survival and Survival Without Morbidities
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