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342361por Sablich, Renato, Urbano, Maria Teresa, Scarpa, Marco, Scognamiglio, Federico, Paviotti, Alberto, Savarino, Edoardo“…There are no prospective, head-to-head, controlled trials comparing the efficacy and safety of Infliximab (IFX) and Vedolizumab (VDZ) for the treatment of moderate-to-severe ulcerative colitis (UC), while only a few real-life retrospective studies have been published so far. …”
Publicado 2023
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342362“…Randomized controlled trials testing the effects of iCBT on psychological outcomes and work engagement among employees will be eligible. …”
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342363“…METHODS: PubMed and EMBASE databases were searched on September 2022 without language restrictions (CRD42022360399) to identify prospective trials and observational studies comparing patients with and without vaccination before severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. …”
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342364por Ruiz, Juan Ignacio, Lopez-Olivo, Maria Angeles, Geng, Yimin, Suarez-Almazor, Maria E“…The review included clinical trials, observational cohort studies, case series, and case reports reporting on the clinical efficacy and safety of COVID-19 vaccines on patients with cancer treated with ICI. …”
Publicado 2023
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342365por Wang, Cuicui, Feng, Zhe, Cai, Jinchen, Duan, Mingda, Li, Huan, Dai, Ziqing, Lv, Hao, Xu, Zhe, Wang, Henglin, Chen, Yu“…We therefore undertook a systematic review and meta-analysis of clinical trials that investigated the diagnostic value of SVV and PPV in predicting fluid responsiveness undergoing OLV during thoracic surgery. …”
Publicado 2023
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342366por Tricco, Andrea C, Hezam, Areej, Parker, Amanda, Nincic, Vera, Harris, Charmalee, Fennelly, Orna, Thomas, Sonia M, Ghassemi, Marco, McGowan, Jessie, Paprica, P Alison, Straus, Sharon E“…MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL) and the Cochrane Database of Systematic Reviews (CDSR) were searched from 2009 until June 2021. …”
Publicado 2023
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342367por Elliott, Jesse, Kelly, Shannon E., Bai, Zemin, Skidmore, Becky, Boucher, Michel, So, Derek, Wells, George A.“…We searched electronic databases (Embase, MEDLINE, PubMed, Cochrane Library) and grey literature (from inception to Nov. 5, 2021) and included randomized controlled trials (RCTs) of extended DAPT (> 12 mo) compared with DAPT for 6–12 months following PCI with stenting. …”
Publicado 2023
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342368por Chiang, Hsueh-Chien, Lee, Yang-Cheng, Chang, Ting-Tsung, Lin, Yih-Jyh, Wu, Hung-Tsung, Wang, Chung-Teng, Chen, Chiung-Yu, Chen, Po-Jun, Hsieh, Ming-Tsung, Lin, Sheng-Hsiang, Chen, Shang-Hung, Chuang, Chiao-Hsiung, Wu, I-Chin, Hong, Tzu-Chun, Wu, Juei-Seng, Han, Meng-Zhi, Chen, Wei-Ting, Chiang, Chien-Ming, Hung, Kuan-Kai, Kuo, Hsin-Yu“…SIMPLE SUMMARY: Immunotherapy using immune checkpoint inhibitors (ICIs) (e.g., programmed cell death protein-1 (PD-1) inhibitors) combined with molecular targeted agents has been evaluated in clinical trials and has shown potential synergic effects and superior efficacy in unresectable hepatocellular carcinoma (uHCC). …”
Publicado 2023
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342369por Yamai, Takuo, Ikezawa, Kenji, Sugimoto, Naotoshi, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Nakabori, Tasuku, Uehara, Hiroyuki, Kawamura, Takahisa, Kunimasa, Kei, Yamamoto, Sachiko, Wakamatsu, Toru, Hayashi, Takuji, Kukita, Yoji, Fujisawa, Fumie, Inoue, Tazuko, Yamaguchi, Yuko, Yamasaki, Tomoyuki, Honma, Keiichiro, Ohkawa, Kazuyoshi“…Four patients (3.5%) having TMB-H and/or MSI-H were treated with pembrolizumab, and only two patients (1.7%) participated in the clinical trials. Patient characteristics were not significantly different between patients with and without HRD-related gene mutations. …”
Publicado 2023
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342370Workload Assessment of Tractor Operations with Ergonomic Transducers and Machine Learning Techniques“…EERs of the operators were measured in the moderate-heavy to heavy ranges (9–24 kJ/min) during the course of trials, suggesting the need to refine existing clutch and brake system designs. …”
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342371por Kooner, Harkiran K., McIntosh, Marrissa J., Matheson, Alexander M., Abdelrazek, Mohammed, Albert, Mitchell S., Dhaliwal, Inderdeep, Kirby, Miranda, Ouriadov, Alexei, Santyr, Giles E., Venegas, Carmen, Radadia, Nisarg, Svenningsen, Sarah, Nicholson, J. Michael, Parraga, Grace“…VDP measured at 3 months after infection correlated with improved exercise capacity, while treatment with respiratory medication was associated with an improved quality-of-life score 15 months after infection. ClinicalTrials.gov registration no. NCT05014516 © RSNA, 2023 Supplemental material is available for this article. …”
Publicado 2023
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342372por Li, Xia, Yang, Le, Li, Dongjing, Yang, Xuying, Wang, Zhijing, Chen, Mengyi, Wu, Fang, Dou, Xiangjun, Niu, Mengmeng, Qi, HongYan, Deng, Ting, Xia, Han, Wang, Dong“…Furthermore, research needs to be better validated in large-scale clinical trials to improve the clinical applications of cfDNA mNGS. …”
Publicado 2023
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342373por Kackos, Christina M., Surman, Sherri L., Jones, Bart G., Sealy, Robert E., Jeevan, Trushar, Davitt, Christopher J. H., Pustylnikov, Sergei, Darling, Tamarand L., Boon, Adrianus C. M., Hurwitz, Julia L., Samsa, Marcelo M., Webby, Richard J.“…These results support the progression of GreenLight Biosciences SARS-CoV-2 mRNA vaccines to clinical trials as another defense against SARS-CoV-2.…”
Publicado 2023
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342374por Ashworth, Jordan, Mathie, Dayna, Scott, Fiona, Mahendran, Yuvaraj, Woolhouse, Mark, Stoevesandt, Oda, Mduluza, Takafira, Mutapi, Francisca“…INTERPRETATION: The effect of these cross-reactive antibodies on SARS-CoV-2 infection or COVID-19 is unknown; however, these antibodies should be considered when interpreting SARS-CoV-2 seroepidemiology studies and evaluating outcomes of COVID-19 vaccine trials in Africa. This study also calls for further characterisation of SARs-CoV-2 immune phenotypes and responses in African populations. …”
Publicado 2023
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342375por Rosato, Rosalba, Palazzo, Valentina, Borghi, Felice, Camanni, Marco, Puppo, Andrea, Delpiano, Elena Maria, Pellegrino, Luca, Piovano, Elisa, Rizzo, Alessio, Rolfo, Monica, Morino, Mario, Allaix, Marco Ettore, Testa, Silvia, Ciccone, Giovannino, Pagano, Eva“…The validation was performed suppling the QoR-15I to 3,784 patients enrolled in two parallel stepped wedge cluster randomised trials (ERAS Colon-rectum Piemonte; ERAS Gyneco Piemonte). …”
Publicado 2023
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342376“…Methods: Randomized controlled trials (RCTs) on the resistance training in improving bone mineral density for postmenopausal women were searched in databases including ProQuest, PubMed, Cochrane Library, Embase, and Web of Science. …”
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342377por Rühle, Alexander, Marschner, Sebastian, Haderlein, Marlen, Fabian, Alexander, Weymann, Maria, Behrens, Max, Senger, Carolin, Dickstein, Daniel R., Kraft, Johannes, von der Grün, Jens, Chen, Eric, Aquino-Michaels, Todd, Domschikowski, Justus, Bickel, Amanda, Altay-Langguth, Alev, Kalinauskaite, Goda, Lewitzki, Victor, Ferentinos, Konstantinos, Zamboglou, Constantinos, Schnellhardt, Sören, Haehl, Erik, Spohn, Simon K.B., Gkika, Eleni, Zöller, Daniela, Guckenberger, Matthias, Budach, Volker, Belka, Claus, Bakst, Richard, Mayer, Arnulf, Schmidberger, Heinz, Grosu, Anca-Ligia, Balermpas, Panagiotis, Stromberger, Carmen, Nicolay, Nils H.“…IMPORTANCE: The number of older adults with head and neck squamous cell carcinoma (HNSCC) is increasing, and these patients are underrepresented in clinical trials. It is unclear whether the addition of chemotherapy or cetuximab to radiotherapy is associated with improved survival in older adults with HNSCC. …”
Publicado 2023
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342378por Yang, Zhenzhen, Wang, Jieya, Yuan, Ye, Cheng, Tian, Ren, Feifei, Wang, Songsong, Zhang, Zhiqing“…However, no randomized controlled trials (RCTs) of warfarin in combination with any non-vitamin K oral anticoagulant (NOACs) have been performed in patients with baseline creatinine clearance (CrCl) <25 ml/min, which makes it difficult to justify the use of anticoagulants in such patients. …”
Publicado 2023
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342379por Wiik, Johanna, Værnesbranden, Magdalena R., Jonassen, Christine M., Staff, Anne Cathrine, Carlsen, Karin C. L., Granum, Berit, Haugen, Guttorm, Hedlin, Gunilla, Hilde, Katarina, Jacobsson, Bo, Nilsson, Staffan, Nordlund, Björn, Rangberg, Anbjørg, Rehbinder, Eva Maria, Sengpiel, Verena, Skjerven, Håvard, Sundet, Birgitte K., Söderhäll, Cilla, Vettukattil, Riyas, Sjøborg, Katrine“…MATERIAL AND METHODS: In pregnant women, who were participating in a prospective multicenter cohort study from a general population in Norway and Sweden (PreventADALL, ClinicalTrials.gov NCT02449850), HPV DNA was analyzed in available urine samples at mid‐gestation (16–22 weeks) and at delivery, and in the placenta after delivery with Seegene Anyplex II HPV28 PCR assay. …”
Publicado 2023
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342380por Tuninetti, Valentina, Ghisoni, Eleonora, Pignata, Sandro, Picardo, Elisa, Raspagliesi, Francesco, Andreetta, Claudia, Maldi, Elena, Artioli, Grazia, Mammoliti, Serafina, Zanchi, Lucia, Sikokis, Angelica, Biglia, Nicoletta, Parisi, Alessandro, Mandato, Vincenzo Dario, Carella, Claudia, Cormio, Gennaro, Marinaccio, Marco, Puppo, Andrea, Paolini, Biagio, Borsotti, Lucia, Scotto, Giulia, Turinetto, Margherita, Sangiolo, Dario, Di Maio, Massimo, Valabrega, Giorgio“…PFS and OS are in line with registration trials. Conclusions: Ki67 at diagnosis did not discriminate responders to PARPi.…”
Publicado 2023
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