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342461por Palomba, Stefano, Costanzi, Flavia, Nelson, Scott M., Caserta, Donatella, Humaidan, Peter“…A systematic review of systematic reviews of randomized controlled trials (RCTs) with meta-analysis was used to assess each potential intervention (PROSPERO website, CRD 268626) and only studies with the highest quality were included in the qualitative analysis. …”
Publicado 2023
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342462“…METHODS: Exit interviews were conducted with patients with T2D participating in the SURPASS-2 and SURPASS-3 trials for tirzepatide. The exit interviews included a concept elicitation section focusing on the emotional impact of their study treatment. …”
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342463por Schwarz, Karine, Cielo, Carla Aparecida, Spritzer, Poli Mara, Villas-Boas, Anna Paula, Costa, Angelo Brandelli, Fontanari, Anna Martha Vaitses, Costa Gomes, Bruna, da Silva, Dhiordan Cardoso, Schneider, Maiko Abel, Lobato, Maria Inês Rodrigues“…METHODS: We searched the PubMed, Lilacs, and SciELO databases for observational studies and clinical trials, published in English, Portuguese, or Spanish, between January 2010 and January 2023. …”
Publicado 2023
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342464“…This meta-analysis selection included randomized controlled trials (RCTs), involving high-intensity statin pretreatment as active treatment, and measurement of thrombolysis in myocardial infarction (TIMI), myocardial blush grade (MBG) or index of microvascular resistance (IMR) in coronary heart disease (CHD) patients undergoing PCI. …”
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342465“…METHODS: Literature was retrieved from 10 commonly used databases and randomized controlled trials published up to May 2022 were sought. The included studies compared the intervention effects of dexmedetomidine versus placebo on anesthesia-related complications in surgery. …”
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342466“…Pelitinib is known to be an irreversible epidermal growth factor receptor tyrosine kinase inhibitor that is used in clinical trials for colorectal and lung cancers, but the role of pelitinib in cancer metastasis has not been studied. …”
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342467“…METHODS: We have identified studies from the Cochrane Central Register of Controlled Trials, PubMed, Embase, and China national knowledge infrastructure (CNKI) for studies interested in TGF-β and proliferation and differentiation of dental pulp stem cells in the following indicators: A490 (an index for evaluating cell proliferation), bone sialoprotein (BSP), Col plasmid-1 (Col-1), osteocalcin (OCN), runt-related transcription factor 2 (Runx-2); and the number of mineralized nodules. …”
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342468por Singla, Ravi, Niederer, Daniel, Franz, Alexander, Happ, Kevin, Zilkens, Christoph, Wahl, Patrick, Behringer, Michael“…Thereof, 13 were non-randomized controlled trails (moderate overall risk of bias in most studies) and 7 were randomized controlled trials (high risk of bias in at least one domain in most studies). …”
Publicado 2023
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342469“…We searched the PubMed, Embase, Cochrane Library, and ClinicalTrials.gov databases for cohort studies that reported on the pulmonary function of patients with hiatal hernias. …”
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342470por Di Marco, Tobias, Scammell, Thomas E., Meinel, Michael, Seboek Kinter, Dalma, Datta, Alexandre N., Zammit, Gary, Dauvilliers, Yves“…CONCLUSION: Daridorexant reduced the number and duration of longer wake bouts throughout the night compared with placebo, corresponding with improved daytime functioning. CLINICAL TRIALS: Clinicaltrials.gov NCT02839200 (registered July 20, 2016), NCT03545191 (registered June 4, 2018). …”
Publicado 2023
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342471por Lim, S. E. R., Meredith, S. J., Agnew, S., Clift, E., Ibrahim, K., Roberts, H. C.“…CONCLUSIONS: Trained volunteers can safely deliver online group exercise for community-dwelling older adults which was acceptable to older adults, volunteers, and club staff. TRIALS REGISTRATION: NCT04672200.…”
Publicado 2023
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342472por Johnson, Leigh F., Kubjane, Mmamapudi, de Voux, Alex, Ohrnberger, Julius, Tlali, Mpho“…The model was applied to South Africa and was calibrated using data from randomized controlled trials of alcohol counselling interventions (n = 9) and gender-transformative interventions (n = 4) in sub-Saharan Africa. …”
Publicado 2023
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342473por Palomba, Stefano, Carone, Domenico, Vitagliano, Amerigo, Costanzi, Flavia, Fracassi, Alice, Russo, Tiziana, Del Negro, Serena, Biello, Altiero, Di Filippo, Aldo, Mangiacasale, Antonio, Monaco, Antonio, Ranieri, Antonio, Ermini, Beatrice, Barba, Bruno Francesco, Castello, Claudio, Di Guardo, Federica, Pastorella, Francesco, Bernasconi, Elena, Tricarico, Ezio Michele, Filippi, Francesca, Polsinelli, Francesco, Monte, Giuseppe Lo, Sosa Fernandez, Loredana M., Galletta, Marco, Giardina, Paolo, Totaro, Pasquale, Laganara, Roberto, Liguori, Roberto, Buccheri, Matteo, Montanino Oliva, Mario, Piscopo, Rosita, Iuliano, Assunta, Innantuoni, Nicola, Romanello, Irene, Sinatra, Francesco, Liprino, Annalisa, Thiella, Roberto, Tiezzi, Alessandra, Bartolotti, Tiziana, Tomasi, Alessandra, Finocchiaro, Valeria, Thiella, Mario, Fuggetta, Giuseppa, Messineo, Sebastiano, Isabella, Francesco, Tripodi, Marcello, Iaccarino, Stefania, La Sala, Giovanni Battista, Papaleo, Enrico, Caserta, Donatella, Marci, Roberto, Somigliana, Edgardo, Guglielmino, Antonino“…Moreover, recent systematic reviews with meta-analyses and randomized controlled trials demonstrated that ES is not effective, data on the safety are limited, and it should not be recommended in clinical practice. …”
Publicado 2023
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342474por Spolverato, Gaya, Fassan, Matteo, Capelli, Giulia, Scarpa, Melania, Negro, Silvia, Chiminazzo, Valentina, Kotsafti, Andromachi, Angriman, Imerio, Campi, Michela, De Simoni, Ottavia, Ruffolo, Cesare, Astghik, Stepanyan, Vignotto, Chiara, Scognamiglio, Federico, Becherucci, Giulia, Rivella, Giorgio, Marchegiani, Francesco, Facci, Luca, Bergamo, Francesca, Brignola, Stefano, Businello, Gianluca, Guzzardo, Vincenza, Dal Santo, Luca, Salmaso, Roberta, Massani, Marco, Pozza, Anna, Cataldo, Ivana, Stecca, Tommaso, Dei Tos, Angelo Paolo, Zagonel, Vittorina, Pilati, Pierluigi, Franzato, Boris, Scapinello, Antonio, Pirozzolo, Giovanni, Recordare, Alfonso, Merenda, Roberto, Bordignon, Giovanni, Guerriero, Silvio, Romiti, Chiara, Portale, Giuseppe, Cipollari, Chiara, Zizzo, Maurizio, Porzionato, Andrea, Agostini, Marco, Cavallin, Francesco, Di Camillo, Barbara, Bardini, Romeo, Maretto, Isacco, Castagliuolo, Ignazio, Pucciarelli, Salvatore, Scarpa, Marco“…A subanalysis of the two IMMUNOREACT trials (NCT04915326 and NCT04917263) was performed, aiming to detect gender-related differences in the immune microenvironment of the healthy mucosa in patients with early (IMMUNOREACT 1 cohort) and locally advanced rectal cancer following neoadjuvant therapy (IMMUNOREACT 2 cohort). …”
Publicado 2023
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342475por Garrett, Matthew C., Albano, Rebecca, Carnwath, Troy, Elahi, Lubayna, Behrmann, Catherine A., Pemberton, Merissa, Woo, Daniel, O’Brien, Eric, VanCauwenbergh, Brett, Perentesis, John, Shah, Sanjit, Hagan, Matthew, Kendler, Ady, Zhao, Chuntao, Paranjpe, Aditi, Roskin, Krishna, Kornblum, Harley, Plas, David R., Lu, Q. Richard“…Histone deacetylase inhibitors are promising anti-cancer agents and have already been used in clinical trials. However, a clear understanding of their mechanism or gene targets is lacking. …”
Publicado 2023
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342476por Villasanta-Gonzalez, Alejandro, Mora-Ortiz, Marina, Alcala-Diaz, Juan F., Rivas-Garcia, Lorenzo, Torres-Peña, Jose D., Lopez-Bascon, Asuncion, Calderon-Santiago, Monica, Arenas-Larriva, Antonio P., Priego‑Capote, Feliciano, Malagon, Maria M., Eichelmann, Fabian, Perez-Martinez, Pablo, Delgado-Lista, Javier, Schulze, Matthias B., Camargo, Antonio, Lopez-Miranda, Jose“…Moreover, these results also indicate that we need to look closely at isomers to understand the role of this specific compound in T2DM development. Trials registration NCT00924937. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12933-023-01933-1.…”
Publicado 2023
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342477por Mikhail, Jérémie, Funabashi, Martha, Sobczak, Stéphane, Descarreaux, Martin, Pagé, Isabelle“…RESULTS: Sixty percent of the trials showed lower force measured at the force plate than the one applied at T7. …”
Publicado 2023
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342478por Rijs, Zeger, Weekhout, Amber, Daniel, Stef, Schoones, Jan W., Groot, Olivier Q., Lozano-Calderon, Santiago A., van de Sande, Michiel A. J.“…However, high-quality randomized controlled trials (RCTs) with long-term follow-up are strongly recommended to provide additional evidence supporting the use of CF plates. …”
Publicado 2023
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342479“…METHODS: Randomized controlled trials (RCTs) or observational studies comparing InterTAN with proximal femoral nail anti-rotation (PFNA), the Asian PFNA (PFNA-II), or the Gamma3 nail in treating IFF were searched on PubMed, EMBASE, Web of Science and Cochrane Library from inception to April 30, 2023. …”
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342480por Seijas-Amigo, Jose, Mauriz-Montero, Mª José, Suarez-Artime, Pedro, Gayoso-Rey, Mónica, Estany-Gestal, Ana, Casas-Martínez, Antonia, González-Freire, Lara, Rodriguez-Vazquez, Ana, Pérez-Rodriguez, Natalia, Villaverde-Piñeiro, Laura, Castro-Rubinos, Concepción, Espino-Faisán, Esther, Rodríguez-Mañero, Moisés, Cordero, Alberto, González-Juanatey, José R.“…INTRODUCTION: The cognitive safety of monoclonal antibody proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) has been established in clinical trials, but not yet in real-world observational studies. …”
Publicado 2023
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