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  1. 342761
    por Kalkan, Üzeyir, Bakay, Kadir
    Publicado 2022
    “…METHODS: This two-centre, randomized-controlled study included a total of 160 patients who were scheduled for TLH for benign diseases (ClinicalTrials.gov Identifier is NCT05080114 and the first posted date was 15/10/2021). …”
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    A multimodal concept for vaginal cuff closure by modification of the Bakay technique in total laparoscopic hysterectomy: a randomized clinical study
  2. 342762
    por Gansané, Adama, Candrinho, Baltazar, Mbituyumuremyi, Aimable, Uhomoibhi, Perpetua, NFalé, Sagnon, Mohammed, Audu Bala, Guelbeogo, Wamdaogo Moussa, Sanou, Antoine, Kangoye, David, Debe, Siaka, Kagone, Moubassira, Hakizimana, Emmanuel, Uwimana, Aline, Tuyishime, Albert, Ingabire, Chantal M., Singirankabo, Joseph H., Koenker, Hannah, Marrenjo, Dulcisaria, Abilio, Ana Paula, Salvador, Crizologo, Savaio, Binete, Okoko, Okefu Oyale, Maikore, Ibrahim, Obi, Emmanuel, Awolola, Samson Taiwo, Adeogun, Adedapo, Babarinde, Dele, Ali, Onoja, Guglielmo, Federica, Yukich, Joshua, Scates, Sara, Sherrard-Smith, Ellie, Churcher, Thomas, Fornadel, Christen, Shannon, Jenny, Kawakyu, Nami, Beylerian, Emily, Digre, Peder, Tynuv, Kenzie, Gogue, Christelle, Mwesigwa, Julia, Wagman, Joseph, Adeleke, Monsuru, Adeolu, Ande Taiwo, Robertson, Molly
    Publicado 2022
    “…CONCLUSIONS: Evidence of the effectiveness and cost-effectiveness of the dual-AI ITNs from these pilot studies will complement evidence from two contemporary cluster randomized control trials, one in Benin and one in Tanzania, to provide key information to malaria control programmes, policymakers, and donors to help guide decision-making and planning for local malaria control and elimination strategies. …”
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    Online Artículo Texto
    Design and methods for a quasi-experimental pilot study to evaluate the impact of dual active ingredient insecticide-treated nets on malaria burden in five regions in sub-Saharan Africa
  3. 342763
    “…Randomized controlled clinical trials are required to further demonstrate its efficacy and optimal application scenario.…”
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    Online Artículo Texto
    Nanoparticle albumin-bound paclitaxel and PD-1 inhibitor (sintilimab) combination therapy for soft tissue sarcoma: a retrospective study
  4. 342764
    “…RESULTS: Of 3877 studies identified, 19 were eligible for inclusion (eight randomized controlled trials (RCTs)). Studies reported outcomes associated with MRSA (15 studies), vancomycin-resistant Enterococci (VRE) (four studies), Clostridium difficile (two studies), and Gram-negative bacteria (GNB) (two studies). …”
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    Online Artículo Texto
    Approaches to multidrug-resistant organism prevention and control in long-term care facilities for older people: a systematic review and meta-analysis
  5. 342765
    “…Although alectinib had demonstrated promising intracranial efficacy in several clinical trials, data were limited on its CNS activity in real-world settings. …”
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    Online Artículo Texto
    Intracranial efficacy of alectinib in ALK-positive NSCLC patients with CNS metastases—a multicenter retrospective study
  6. 342766
    “…Hundreds of clinical trials have been registered and lots of studies have shown hematologic toxic effects were very common. …”
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    Online Artículo Texto
    Adverse effects in hematologic malignancies treated with chimeric antigen receptor (CAR) T cell therapy: a systematic review and Meta-analysis
  7. 342767
    “…These findings may support trials aiming to scavenger brain extracellular iron based on the hypothesis that iron-mediated neurotoxicity may contribute to acute and secondary brain injury following SAH.…”
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    Intracerebral Iron Accumulation may be Associated with Secondary Brain Injury in Patients with Poor Grade Subarachnoid Hemorrhage
  8. 342768
    “…Similar kinetics of apolipoprotein A1, HP, and alpha-2-macroglobulin were observed in the NHP model. ClinicalTrials.gov number, NCT01927133.…”
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    Online Artículo Texto
    Validation of the Performance of A1HPV6, a Triage Blood Test for the Early Diagnosis and Prognosis of SARS-CoV-2 Infection
  9. 342769
    “…ERSs that involved face-to-face consultations and telephone calls had the highest rates of mean uptake (91.5%) and adherence (71.7%), but a difference was observed between uptake/adherence in trials (86.8%/55.3%) and in routine practice (57.9%/37.2%). …”
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    Online Artículo Texto
    Evaluation of the uptake, retention and effectiveness of exercise referral schemes for the management of mental health conditions in primary care: a systematic review
  10. 342770
    por Pizzuti, Laura, Krasniqi, Eriseld, Sperduti, Isabella, Barba, Maddalena, Gamucci, Teresa, Mauri, Maria, Veltri, Enzo Maria, Meattini, Icro, Berardi, Rossana, Di Lisa, Francesca Sofia, Natoli, Clara, Pistelli, Mirco, Iezzi, Laura, Risi, Emanuela, D’Ostilio, Nicola, Tomao, Silverio, Ficorella, Corrado, Cannita, Katia, Riccardi, Ferdinando, Cassano, Alessandra, Bria, Emilio, Fabbri, Maria Agnese, Mazzotta, Marco, Barchiesi, Giacomo, Botticelli, Andrea, D’Auria, Giuliana, Ceribelli, Anna, Michelotti, Andrea, Russo, Antonio, Salimbeni, Beatrice Taurelli, Sarobba, Giuseppina, Giotta, Francesco, Paris, Ida, Saltarelli, Rosa, Marinelli, Daniele, Corsi, Domenico, Capomolla, Elisabetta Maria, Sini, Valentina, Moscetti, Luca, Mentuccia, Lucia, Tonini, Giuseppe, Raffaele, Mimma, Marchetti, Luca, Minelli, Mauro, Ruggeri, Enzo Maria, Scavina, Paola, Bacciu, Olivia, Salesi, Nello, Livi, Lorenzo, Tinari, Nicola, Grassadonia, Antonino, Fedele Scinto, Angelo, Rossi, Rosalinda, Valerio, Maria Rosaria, Landucci, Elisabetta, Stani, Simonetta, Fratini, Beatrice, Maugeri-Saccà, Marcello, De Tursi, Michele, Maione, Angela, Santini, Daniele, Orlandi, Armando, Lorusso, Vito, Cortesi, Enrico, Sanguineti, Giuseppe, Pinnarò, Paola, Cappuzzo, Federico, Landi, Lorenza, Botti, Claudio, Tomao, Federica, Cappelli, Sonia, Bon, Giulia, Pelle, Fabio, Cavicchi, Flavia, Fiorio, Elena, Foglietta, Jennifer, Scagnoli, Simone, Marchetti, Paolo, Ciliberto, Gennaro, Vici, Patrizia
    Publicado 2021
    “…Prospective randomized trials addressing this topic are awaited.…”
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    Online Artículo Texto
    PANHER study: a 20-year treatment outcome analysis from a multicentre observational study of HER2-positive advanced breast cancer patients from the real-world setting
  11. 342771
    “…METHODS: PubMed, Pedro, Web of Science, and EMBASE databases were searched for randomized controlled trials, cohort studies, case-control studies, and cross-sectional studies published in the English language from 2000 to 2020. …”
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    Effective interventions to improve long-term physiotherapy exercise adherence among patients with lower limb osteoarthritis. A systematic review
  12. 342772
    “…The presence of cirrhosis and its stage should be evaluated at baseline to guide for management. Thai Clinical Trials Registry, TCTR20191226002. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12072-021-10266-8.…”
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    Impact of compensated cirrhosis on survival in patients with acute-on-chronic liver failure
  13. 342773
    “…However, these results need to be further confirmed via clinical randomized controlled trials.…”
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    Deep learning model for multi-classification of infectious diseases from unstructured electronic medical records
  14. 342774
    “…These findings represent the scientific rationale for testing NOTCH1 inhibitors in clinical trials, taking the first step toward precision medicine for iCCA. …”
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    CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype
  15. 342775
    “…A limited series of five sequentially enrolled patients presented here were from the MutHER (https://www.clinicaltrials.gov, NCT01670877) or SUMMIT (https://www.clinicaltrials.gov, NCT01953926) trials. Patients had an average of 5.4 lines of therapy before enrollment, variable hormone receptor status, and ERBB2 mutations at diagnosis and during treatment. …”
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    Online Artículo Texto
    Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib
  16. 342776
    “…In three randomized controlled trials (RCTs), pooled continuous data showed statistically significant reduction in fatigue scores in women who received iron supplementation than the control group [MD: -1.85 (95% CI: -3.04; -0.67), I(2) = 65.0%, p < 0.06]. …”
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    Effect of postpartum anaemia on maternal health-related quality of life: a systematic review and meta-analysis
  17. 342777
    “…Although myocarditis and pericarditis were not observed as adverse events in coronavirus disease 2019 (COVID-19) vaccine trials, there have been numerous reports of suspected cases following vaccination in the general population. …”
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    Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection
  18. 342778
    “…Thus, monocyte-derived microglia-like cells are highly applicable to monitor disease progression and can be applied as a functional readout in clinical trials for anti-neuroinflammatory agents, providing a basis for personalised treatment for patients with ALS. …”
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    ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression
  19. 342779
    “…Respondents perceived a moderate variation in management decisions between specialists and supported the need for randomised controlled trials to test different management pathways. CONCLUSIONS: Most vascular and orthopaedic surgeons do not use best-practice guidelines to assist in decisions about management of diabetes-related foot infection. …”
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    Opinions about the most appropriate surgical management of diabetes-related foot infection: a cross-sectional survey
  20. 342780
    “…TRAIL REGISTRATION: ClinicalTrials, NCT00666367. Registered 23 April 2008, https://www.clinicaltrials.gov/ct2/show/study/NCT00666367. …”
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    Effects of repeated infections with non-typeable Haemophilus influenzae on lung in vitamin D deficient and smoking mice
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