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  1. 342841
    “…The successful completion of this project will produce a cross-validated prognostic model for LSS that can be used to tailor treatment approaches for patient care and clinical trials. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12891-022-05598-x.…”
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    The Lumbar Stenosis Prognostic Subgroups for Personalizing Care and Treatment (PROSPECTS) study: protocol for an inception cohort study
  2. 342842
    “…Furthermore, randomized controlled trials (RCTs) have established that SGLT2i have a cardioprotective effect in adults with heart failure (HF). …”
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    Effect of sodium-glucose cotransporter-2 inhibitors on blood pressure in patients with heart failure: a systematic review and meta-analysis
  3. 342843
    “…METHODS: A systematic search was conducted of Medline (Ovid), Scopus, Science Direct, Proquest, PsycINFO, CINAHL, PubMed, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials and a number of grey literature sources. Titles and abstracts were screened by one researcher. …”
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    A scoping review of outdoor food marketing: exposure, power and impacts on eating behaviour and health
  4. 342844
    “…Regarding their perceptions of and experiences with specific drug development and approval tools, namely biobanks, disease models, patient registries, natural history studies (NHS) and clinical trials (CT), the CDG community stakeholders described low use and participation, as well as variable familiarity. …”
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    Stakeholders’ views on drug development: the congenital disorders of glycosylation community perspective
  5. 342845
    por Pan, Wan-Lin, Chen, Li-Li, Gau, Meei-Ling
    Publicado 2022
    “…Thus, randomized controlled trials or large-scale prospective cohort studies are necessary. …”
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    Accuracy of non-invasive methods for assessing the progress of labor in the first stage: a systematic review and meta-analysis
  6. 342846
    “…Among continuers, there were few differences in method satisfaction. ClinicalTrials.gov Identifier NCT02734199 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12905-022-01911-x.…”
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    Does access to no-cost contraception change method selection among individuals who report difficulty paying for health-related care?
  7. 342847
    “…Rated as potentially clinically applicable, our tool may be clinically useful to inform diagnostic decisions in dementia, if successful in real-world prospective clinical trials. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13195-022-01047-y.…”
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    Early diagnosis of Alzheimer’s disease using machine learning: a multi-diagnostic, generalizable approach
  8. 342848
    por Wang, Lei, Zhao, Yun-Tao
    Publicado 2022
    “…Therefore, randomized controlled trials of albumin administration are needed for patients with AHF. …”
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    Albumin infusion in hospitalized patients with acute heart failure: a retrospective cohort study
  9. 342849
    “…CONCLUSION: Our results suggest that AmB-D combined with 5FC remains the more efficacious induction regimen compared to AmB-D plus Flu, and that VCZ + 5FC might be a potential alternative when the standard regimen is not readily available, accessible, tolerated, or effective. Clinical Trials: Registration number, ChiCTR1900021195. Registered 1 February 2019, http://www.chictr.org.cn/showproj.aspx?…”
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    Comparison of amphotericin B deoxycholate in combination with either flucytosine or fluconazole, and voriconazole plus flucytosine for the treatment of HIV-associated cryptococcal meningitis: a prospective multicenter study in China
  10. 342850
    “…At present, however, this observational study does not necessarily encourage formula feeding, and randomized controlled trials are warranted to confirm the findings and their significance. …”
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    The association between early formula and reduced risk of cow’s milk allergy during the first three year of life: a Japanese cohort study
  11. 342851
    “…Our results underscore the need to identify opportunities for improving COVID-19 vaccination, implementation of treatment of pregnant women, and the inclusion of pregnant women in clinical trials.…”
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    Characteristics and treatment of hospitalized pregnant women with COVID-19
  12. 342852
    “…METHODS: We searched in eight major databases for all clinical trials discussing the effect of two analgesia regimens after TKA. …”
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    iPACK block (local anesthetic infiltration of the interspace between the popliteal artery and the posterior knee capsule) added to the adductor canal blocks versus the adductor canal blocks in the pain management after total knee arthroplasty: a systematic review and meta-analysis
  13. 342853
    “…BACKGROUND: Mesenchymal stem cells (MSCs) have been extensively used for the treatment of various diseases in preclinical and clinical trials. In vitro propagation is needed to attain enough cells for clinical use. …”
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    Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
  14. 342854
    “…BACKGROUND: Autologous stem cell therapy is a promising strategy for cardiovascular diseases including diabetic cardiomyopathy (DCM), but conclusions from clinical trials were compromised. We assumed that diabetes might induce the dysfunction of stem cells and thus limit its therapeutic effect. …”
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    Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy
  15. 342855
    “…Performing both types of exercise might be the most effective way to prevent sarcopenia that should be investigated in future clinical trials. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-022-03293-z.…”
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    The association of aerobic, resistance, and combined exercises with the handgrip strength of middle-aged and elderly Korean adults: a nationwide cross-sectional study
  16. 342856
    por Bilbao, Ainhoa, Spanagel, Rainer
    Publicado 2022
    “…METHODS: We systematically reviewed (registered at PROSPERO: CRD42021229932) eight databases for randomized controlled trials (RCTs) of dronabinol, nabilone, cannabidiol and nabiximols for chronic pain, spasticity, nausea /vomiting, appetite, ALS, irritable bowel syndrome, MS, Chorea Huntington, epilepsy, dystonia, Parkinsonism, glaucoma, ADHD, anorexia nervosa, anxiety, dementia, depression, schizophrenia, PTSD, sleeping disorders, SUD and Tourette. …”
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    Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications
  17. 342857
    “…METHODS: This post hoc analysis of pooled data from the phase 3 AMAGINE-2 and −3 trials evaluated complete skin clearance (100% improvement of Psoriasis Area and Severity Index [PASI 100]), improvement in symptom severity (Psoriasis Symptom Inventory [PSI] response), and QoL (Dermatology Life Quality Index [DLQI] score of 0/1) by concomitant PsA status. …”
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    Brodalumab Is Associated with High Rates of Complete Clearance and Quality of Life Improvement: A Subgroup Analysis of Patients with Psoriasis and Concomitant Psoriatic Arthritis
  18. 342858
    “…CONCLUSION: Following a single dose of tigecycline, concentrations in the ISF of subcutaneous adipose tissue are decreased in heavily obese subjects, calling for an increased loading dose. EU CLINICAL TRIALS REGISTRATION NUMBER: EudraCT No. 2012-004383-22. …”
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    Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis
  19. 342859
    “…Validation in larger clinical trials with a rigorous gold standard is still required. …”
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    Imaging joint infections using D-methyl-(11)C-methionine PET/MRI: initial experience in humans
  20. 342860
    “…Further prospective randomized control clinical trials designed to explore alternative irAE management options are warranted.…”
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    Early Use of High-Dose Glucocorticoid for the Management of irAE Is Associated with Poorer Survival in Patients with Advanced Melanoma Treated with Anti–PD-1 Monotherapy
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