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342961“…However, there still were certain limitations in this study, so large-sample clinical randomized control trials with a rigor design following the evidence-based medicine standards need to be conducted to justify the results of this study. …”
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342962por Thomma, Robin C.M., Fokke, Christiaan, Walgaard, Christa, Vermeulen-de Jongh, Denise M.C., Tio-Gillen, Anne, van Rijs, Wouter, van Doorn, Pieter A., Huizinga, Ruth, Jacobs, Bart C.“…METHODS: Acute-phase sera from patients with GBS included in previous therapeutic trials were screened for anti-GM1 IgG and IgM antibodies in ELISA. …”
Publicado 2023
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342963por Zhao, Xiao, Wang, Jennifer Rui, Dadu, Ramona, Busaidy, Naifa Lamki, Xu, Lei, Learned, Kim O., Chasen, Noah N., Vu, Thinh, Maniakas, Anastasios, Eguia, Arturo A., Diersing, Julia, Gross, Neil D., Goepfert, Ryan, Lai, Stephen Y., Hofmann, Marie-Claude, Ferrarotto, Renata, Lu, Charles, Gunn, Gary Brandon, Spiotto, Michael T., Subbiah, Vivek, Williams, Michelle D., Cabanillas, Maria E., Zafereo, Mark E.“…These promising results of neoadjuvant BRAF-directed therapy followed by surgery for BRAF-mutated ATC should be confirmed in prospective clinical trials.…”
Publicado 2023
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342964por Sharma, Sandhya, Woods, Mae, Mehta, Naren U, Sauer, Tim, Parikh, Kathan S, Schmueck-Henneresse, Michael, Zhang, Huimin, Mehta, Birju, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M“…Having overcome our inability to generate EBVSTs from many patients with lymphoma, we have introduced CD45RA depletion into three clinical trials: NCT01555892 and NCT04288726 using autologous and allogeneic EBVSTs to treat lymphoma and NCT04013802 using multivirus-specific T cells to treat viral infections after hematopoietic stem cell transplantation.…”
Publicado 2023
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342965por Steindal, Simen A, Nes, Andréa Aparecida Gonçalves, Godskesen, Tove E, Holmen, Heidi, Winger, Anette, Österlind, Jane, Dihle, Alfhild, Klarare, Anna“…A systematic search was performed in the following databases: Allied and Complementary Medicine Database, CINAHL, Cochrane Central Register of Controlled Trials, Embase, Latin American and Caribbean Health Sciences Literature, MEDLINE, PsycInfo, and Web of Science. …”
Publicado 2023
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342966por Cao, Biyang, Zhang, Letian, Wu, Chenchen, Liu, Xiaoliang, Wang, Qianqian, Tong, Fang, Yang, Wei, Wang, Jing“…Further prospective randomized trials are warranted to validate our results in these patients.…”
Publicado 2023
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342967por Lin, Lizhen, Li, Chengchen, Ren, Zongling, Qin, Yuzhi, Wang, Ruilong, Wang, Jia, Cai, Jianying, Zhao, Lanfeng, Li, Xiaobo, Cai, Yanfei, Xiong, Xingyao“…Compared with the control group (CK), P68 significantly increased the yield of potato commercial tubers by 17.02% and P accumulation by 27.31% in the field. Similarly, pot trials showed that the application of P68 significantly increased the biomass, total phosphorus content of the potato plants, and available phosphorus of the soil up by 32.33, 37.50, and 29.15%, respectively. …”
Publicado 2023
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342968“…OBJECTIVE: This study aims to assess the current status of internet-based PND intervention platforms supported by published evidence, understand the reasons behind the disappearance of any of these previously accessible platforms, examine adjustments made by those active platforms between research trials and market implementation, and evaluate their current quality. …”
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342969por Kobeissi, Hassan, Ghozy, Sherief, Adusumilli, Gautam, Kadirvel, Ramanathan, Brinjikji, Waleed, Rabinstein, Alejandro A., Kallmes, David F.“…IMPORTANCE: Previous randomized clinical trials (RCTs) have supported the use of endovascular therapy (EVT) in late-window acute ischemic stroke (AIS; 6-24 hours). …”
Publicado 2023
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342970por Jensen, Erik A., Wiener, Laura Elizabeth, Rysavy, Matthew A., Dysart, Kevin C., Gantz, Marie G., Eichenwald, Eric C., Greenberg, Rachel G., Harmon, Heidi M., Laughon, Matthew M., Watterberg, Kristi L., Walsh, Michele C., Yoder, Bradley A., Lorch, Scott A., DeMauro, Sara B.“…Whether this association exists in contemporary practice is uncertain because most randomized clinical trials administered corticosteroids earlier and at higher doses than currently recommended. …”
Publicado 2023
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342971“…Knowledge on fibroid prevalence, especially in the asymptomatic population and in Asian and Hispanic or Latina individuals, is limited, and a better understanding of affected groups will improve timely diagnosis and motivate appropriate recruitment in clinical trials to reduce health disparities. OBJECTIVE: To estimate the prevalence of fibroids in a diverse cohort of female individuals. …”
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342972por Lang, Lijian, Wang, Tianwei, Xie, Li, Yang, Chun, Skudder-Hill, Loren, Jiang, Jiyao, Gao, Guoyi, Feng, Junfeng“…METHODS: The data were from the Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI) China registry (between Dec 22, 2014, and Aug 1, 2017; registered at ClinicalTrials.gov, NCT02210221). This analysis included information of eligible patients with diagnosed sTBI from 52 centres (2631 cases). 1808 cases from 36 centres were enrolled in the training group (used to construct the nomogram) and 823 cases from 16 centres were enrolled in the validation group. …”
Publicado 2023
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342973por Giofrè, Claudia, Fabbrocini, Gabriella, Potenza, Concetta, Tiberio, Rossana, Gisondi, Paolo, Marasca, Claudio, Nuzzo, Carmen M. A., Benincasa, Emiliana, Bianchi, Luca“…STUDY REGISTRATION: ClinicalTrials.gov identifier, NCT04031027. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12325-023-02516-y.…”
Publicado 2023
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342974“…METHODS: We selected Web of Science, ScienceDirect, Scopus, Cochrane library, IEEE, and Chinese National Knowledge Infrastructure and Wanfang, a Chinese medical database, and searched papers published from January 1, 2015, to July 1, 2022, regarding randomized controlled trials on the effectiveness of the telehealth system on patients with chronic diseases. …”
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342975por Miao, Qi, Wei, Zhihao, Liu, Chenchen, Ye, Yuzhong, Cheng, Gong, Song, Zhengshuai, Chen, Kailei, Zhang, Yunxuan, Chen, Jiawei, Yue, Changjie, Ruan, Hailong, Zhang, Xiaoping“…The limitation of this article is that it is not possible to assess the effect of differences in systemic therapy on CSM in mPCa patients and clinical trials are needed to verify the results. CONCLUSIONS: For patients with mPCa, both RP and RT are beneficial to patients, and the efficacy of RP is better than RT from the perspective of CSM and ACM. …”
Publicado 2023
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342976por Eldhagen, Per, Lehtonen, Jukka, Gude, Einar, Gustafsson, Finn, Bagger‐Bahnsen, Anne, Vakevainen, Merja, Pilgaard, Trine, Wedell‐Wedellsborg, Dorte, Poulsen, Steen Hvitfeldt“…Participation in randomized clinical trials (RCT) was noted in 58% of the patients. The 169 ATTR CM patients had a mean ± SD KCCQ score of 64.3 ± 23.1 for total symptom score, 64.8 ± 20.9 for overall summary score (OSS) and 65.1 ± 21.5 for clinical summary score. …”
Publicado 2023
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342977por Leite, Marta, Sampaio, Francisco, Saraiva, Francisca A., Diaz, Sílvia O., Barros, António S., Fontes‐Carvalho, Ricardo“…HFmrEF treatment is often considered a grey zone as no randomized controlled trials (RCTs) were conducted exclusively on these patients. …”
Publicado 2023
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342978“…CONCLUSION: CONUT is a simple and strong prognostic indicator for the prediction of all-cause mortality in older adults with HFpEF. CLINICAL TRIALS.GOV IDENTIFIER: NCT05586828.…”
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342979“…BACKGROUND: Several clinical trials of corticosteroids have been carried out in the treatment of septic shock, however, the therapeutic effect of the most widely used hydrocortisone is still controversial, and no studies have directly compared hydrocortisone versus hydrocortisone plus fludrocortisone for patients with septic shock. …”
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342980por Olivier, Margarete, Kavvalou, Alexandra, Welsner, Matthias, Hirtz, Raphael, Straßburg, Svenja, Sutharsan, Sivagurunathan, Stehling, Florian, Steindor, Mathis“…Conclusion: In a real-world setting, elexacaftor/tezacaftor/ivacaftor therapy had beneficial clinical effects and a good safety profile in eligible children with cystic fibrosis comparable to previously published data from controlled clinical trials. The positive impact on pulmonary function tests and nutritional status seen after 3 months of elexacaftor/tezacaftor/ivacaftor therapy was sustained at 6 months follow-up.…”
Publicado 2023
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