“…METHODS: We searched the CNKI, Wanfang, VIP, SinoMed, PubMed, Embase, Cochrane Library, and Web of Science databases for all randomized controlled trials (RCTs) of NMES in the treatment of post-stroke dysphagia from the establishment of the database to 9 June 2022. …”
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“…The impact of PWA on arrhythmia-free outcome needs to be evaluated in larger, prospective randomized trials. [Figure: see text]…”
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“…Amiodarone was superior in lowering the AHRE burden when compared to Ic antiarrhythmics and beta-blockers (2.1% vs 5.6% and 7.8%, respectively, p<0.001), while no significant differences were observed between Ic antiarrhythmics and beta-blockers (p=0.18) CONCLUSION: Initiating antiarrhythmics for AHRE episodes leads to a lower AHRE burden and progression to clinical AF. Randomized clinical trials are needed to investigate further the early antiarrhythmic treatment of AHRE without clinical AF. …”
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“…However, data on the long-term outcomes of cardiac resynchronization therapy (CRT) in patients with chronic kidney disease is scarce due to underrepresentation of such patients in clinical trials on CRT. AIM: To determine outcome and mortality predictors in patients with HF and elevated creatinine level treated with cardiac resynchronization therapy. …”
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“…METHOD: In a block randomized, crossover, double-blind, placebo-controlled design, 14 recreationally trained male team sport athletes performed a familiarization visit and three experimental trials receiving: (i) 0.3 g·kg(−1) body mass (BM) NaHCO(3) in capsules + placebo lotion (SB-ORAL), (ii) placebo capsules +0.9036 g·kg(−1) BM PR Lotion (SB-LOTION), or (iii) placebo capsules + placebo lotion (PLA). …”
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“…These differences may have implications for targeted therapies and the design of clinical trials in breast cancer. ABSTRACT: Background: Molecular subtyping of breast cancer has provided a new perspective on the pathogenesis of the disease and a foundation for building a clinical classification for this heterogeneous disease. …”
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“…ABSTRACT: This study quantified the differences in the efficacy and safety of different stimulation domains of anti-CD19 chimeric antigen receptor (CAR) T therapy for B-cell acute lymphoblastic leukemia (B-ALL). Clinical trials related to anti-CD19 CAR T-cell therapy for B-ALL were searched in public databases from database inception to 13 November 2021. …”
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“…Hence, there is a need to do more work (eg, cross-cultural studies and randomized controlled trials) among the growing aging population on the effectiveness and acceptance of smart home technologies that aim to promote physical activity.…”
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“…In the future, more randomized controlled trials with large-sample, high quality, and follow-up are necessary to explore a usable protocol further. …”
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“…The prognostic model constituted of VSIG4, HLA-DRA, SERPINF1, and IGLV2-23 can significantly predict the prognosis of ccRCC patients, but this still needs more clinical trials to verify.…”
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“…METHODS: We searched PubMed, EMBASE, Web of Science, The Cochrane Library, and ClinicalTrials (from January 1, 1975 to November 1, 2021). …”
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“…Since ICIs enable adaptive antitumor immune responses, we investigated T-cell receptor (TCR) associations with survival in participants from two clinical trials treated with ICI. METHODS: We included patients with pleural mesothelioma who were treated with nivolumab (NivoMes, NCT02497508) or nivolumab and ipilimumab (INITIATE, NCT03048474) after first-line therapy. …”
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“…We searched Embase, MEDLINE (including PubMed), Global Health, Global Index Medicus, Web of Science, and the Cochrane Central Register of Controlled Trials from inception until May 13, 2022. Observational and interventional studies reporting odds ratios (OR), hazard ratios (HR), or sufficient information to reconstruct effect sizes on individual-level associations between water contact and infection with any Schistosoma species were eligible for inclusion. …”
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“…METHODS: Studies in PubMed, Web of Science, Embase, and clinical trials databases were searched from 1 January 2021 to 10 September 2022. …”
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“…The design, development, and usage of vaccines for and in obese individuals may need critical evaluation, and immune history should be considered an alternate correlate of protection in future vaccine clinical trials.…”
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“…Our meta-analysis showed no difference in distal revision rate between laparoscopic and open shunt insertion; however, laparoscopic placement was associated with a significantly shorter surgery time. Further prospective trials are needed to assess possible superiority of one of the techniques.…”
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“…In summary, a human–machine collaborative diagnostic model may assist pathologists in making diagnostic decisions, and further prospective clinical trials are needed to confirm its efficacy. ABSTRACT: (1) Background: The Fuhrman grading (FG) system is widely used in the management of clear cell renal cell carcinoma (ccRCC). …”
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“…The scaffold proteins [(99m)Tc]Tc-ADAPT6 and DARPin [(99m)Tc]Tc-(HE)(3)-G3 have been found to be safe in Phase I clinical trials. They showed promising results in the imaging of HER2. …”
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“…METHODS: PubMed, Google Scholar, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials were queried from January 2020 up to February 2022 to identify studies investigating the effect of fibrinolytic therapy on the prognostic outcome of STEMI patients during the pandemic. …”
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“…The groups were in a 1 : 1 ratio according to the principles of nonrandomised, concurrent controlled trials, and methods. There were 60 participants in each group (group A, group B, and group C). …”
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