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  1. 343161
    “…METHODS AND FINDINGS: Whole-exome sequencing was performed on 216 tumor–blood pairs from mBC patients who underwent a biopsy in the context of the SAFIR01, SAFIR02, SHIVA, or Molecular Screening for Cancer Treatment Optimization (MOSCATO) prospective trials. Mutational profiles from 772 primary breast tumors from The Cancer Genome Atlas (TCGA) were used as a reference for comparing primary and mBC mutational profiles. …”
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    Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis
  2. 343162
    “…Our findings support the need to compare the 2 treatments in randomized controlled trials.…”
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    A propensity-matched analysis of surgery and stereotactic body radiotherapy for early stage non-small cell lung cancer in the elderly
  3. 343163
    “…METHODS: Medline, Embase, CINAHL, PsycINFO, PEDro, Web of Science, SciVerse SCOPUS, and Cochrane Central Register of Controlled Trials were searched from June 2014 to March 2016. …”
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    Can screening instruments accurately determine poor outcome risk in adults with recent onset low back pain? A systematic review and meta-analysis
  4. 343164
    “…METHODS: Medline (PubMed), PsychINFO, Cumulative Index for Nursing and Allied Health Professionals (CINAHL), Embase, and Cochrane Central Register of Controlled Trials were searched on August 14, 2015, and March 8, 2016, for English-language papers published between 2006 and 2016. …”
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    Cancer Survivors’ Experience With Telehealth: A Systematic Review and Thematic Synthesis
  5. 343165
    “…However, the low estimated frequency and inconsistency of successful isolation represent open challenges for the use of CB-derived MSC in clinical trials. This study explores whether CB may represent a suitable source of MSC for clinical use and analyzes several in vitro parameters useful to better define the quality of CB-derived MSC prior to clinical application. …”
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    Generation of mesenchymal stromal cells from cord blood: evaluation of in vitro quality parameters prior to clinical use
  6. 343166
    “…BACKGROUND: Four cluster randomized controlled trials (cRCTs) conducted in long-term care facilities (LTCFs) have reported reductions in patient risk through increased healthcare worker (HCW) influenza vaccination. …”
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    Influenza Vaccination of Healthcare Workers: Critical Analysis of the Evidence for Patient Benefit Underpinning Policies of Enforcement
  7. 343167
    “…To date most clinical trials of immunomodulation therapies failed to show efficacy. …”
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    Investigation of coordination and order in transcription regulation of innate and adaptive immunity genes in type 1 diabetes
  8. 343168
    “…Adoptive immunotherapy with Vγ2Vδ2 T cells has been used to treat cancer patients with partial and complete remissions. Most clinical trials and preclinical studies have used continuous zoledronate exposure to expand Vγ2Vδ2 cells where zoledronate is slowly diluted over the course of the culture. …”
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    Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulation
  9. 343169
    “…Due to the limitations of the quality and quantity of included articles, this conclusion still needs to be confirmed by multicenter clinical trials.…”
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    Effect of high-dose rosuvastatin loading before percutaneous coronary intervention in Chinese patients with acute coronary syndrome: A systematic review and meta-analysis
  10. 343170
    “…Standard dosimetric criteria and normal tissue constraints based on recent clinical trials were used in target delineation and planning. …”
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    Reducing radiation dose to normal brain through a risk adapted dose reduction protocol for patients with favourable subtype anaplastic glioma
  11. 343171
    “…Effectiveness of treatment was evaluated in Quality-Adjusted Life-Years (QALYs) and Life-Years Gained (LYG), using inputs from clinical trials for bedaquiline and delamanid and from a German observational study for linezolid. …”
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    Cost-effectiveness of adding novel or group 5 interventions to a background regimen for the treatment of multidrug-resistant tuberculosis in Germany
  12. 343172
    “…The findings are in accord with other mammography screening service evaluations and with randomised trials of mammography screening.…”
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    Mammography service screening and breast cancer mortality in New Zealand: a National Cohort Study 1999–2011
  13. 343173
    “…This study is registered with ClinicalTrials.gov, number NCT02727231, and is completed. …”
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    Day-and-night glycaemic control with closed-loop insulin delivery versus conventional insulin pump therapy in free-living adults with well controlled type 1 diabetes: an open-label, randomised, crossover study
  14. 343174
    “…We highlight the need for a clearly defined TDR and for safety and efficacy trials to focus on doses compatible with age-based dosing often employed in such settings. …”
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    Modelling the therapeutic dose range of single low dose primaquine to reduce malaria transmission through age-based dosing
  15. 343175
    “…The study was registered in ClinicalTrials.gov; identifier: NCT02178501. Registration date: April 12, 2014 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12933-017-0523-9) contains supplementary material, which is available to authorized users.…”
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    Treatment with high-dose n-3 PUFAs has no effect on platelet function, coagulation, metabolic status or inflammation in patients with atherosclerosis and type 2 diabetes
  16. 343176
    “…A fifth intervention, Mental Health Courts, was trialed but has now been abandoned in England and Wales and so has been excluded, but remains in use elsewhere. …”
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    Effectiveness of current policing-related mental health interventions in England and Wales and Crisis Intervention Teams as a future potential model: a systematic review
  17. 343177
    “…This study is registered with ClinicalTrials.gov, number NCT02499172. FINDINGS: We recruited 900 women exposed to oral cholera vaccine and 899 women not exposed to the vaccine between June 16 and Oct 10, 2015, and analysed 835 in each group. 361 women exposed to the vaccine and 327 not exposed to the vaccine were recruited after their pregnancies had ended. …”
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    Safety of a killed oral cholera vaccine (Shanchol) in pregnant women in Malawi: an observational cohort study
  18. 343178
    “…Studies had to be prospective randomized controlled trials (RCTs). In each of the RCTs admitted to meta-analysis, a comparison was made between a group of CHF patients taking a PDE5 inhibitor and a second group assigned a placebo. …”
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    Phosphodiesterase-5 Inhibitors Improve Clinical Outcomes, Exercise Capacity and Pulmonary Hemodynamics in Patients With Heart Failure With Reduced Left Ventricular Ejection Fraction: A Meta-Analysis
  19. 343179
    por Badawy, Sherif M, Kuhns, Lisa M
    Publicado 2017
    “…Although most studies were randomized controlled trials (RCTs; 58%, 11/19), only 5 followed an intent-to-treat analysis. …”
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    Texting and Mobile Phone App Interventions for Improving Adherence to Preventive Behavior in Adolescents: A Systematic Review
  20. 343180
    “…CONCLUSION: New onset autoimmune diabetes mellitus associated with nivolumab has been described only in case reports and occurs at rates of < 1% in the large clinical trials which garnered FDA approval in the second line setting for NSCLC. …”
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    Nivolumab-induced autoimmune diabetes mellitus presenting as diabetic ketoacidosis in a patient with metastatic lung cancer
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