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  1. 343421
    “…Considering the potential limitations in the present study, further large-scale, well-performed randomized trials are needed to verify our findings.…”
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    Percutaneous endoscopic lumbar discectomy compared with other surgeries for lumbar disc herniation: A meta-analysis
  2. 343422
    “…AIMS/HYPOTHESIS: Large cardiovascular outcome trials demonstrated that the cardioprotective effects of sodium–glucose cotransporter 2 (SGLT2) inhibitors might reach beyond glucose-lowering action. …”
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    Sodium–glucose cotransporter 2 inhibitors reduce myocardial infarct size in preclinical animal models of myocardial ischaemia–reperfusion injury: a meta-analysis
  3. 343423
    “…Based on titles and abstracts alone, we were able to identify 1515 surveys, 733 systematic reviews, 512 cohort studies, 480 meta-analyses, and 362 randomized control trials. We identified 19 different topics covered among the publications reviewed. …”
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    A Comprehensive Overview of the COVID-19 Literature: Machine Learning–Based Bibliometric Analysis
  4. 343424
    por Gross, Arthur, Glaser, Bruno
    Publicado 2021
    “…On the other hand, long-term field trials should be re-assessed or newly established to specifically investigate potential saturation effects and long-term (> 20 years) fertilizer effects and carbon sequestration.…”
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    Meta-analysis on how manure application changes soil organic carbon storage
  5. 343425
    “…METHODS: We searched relevant databases including Cochrane Central Register of Controlled Trials, Ovid (MEDLINE, EMBASE, AMED) and EBSCO (CINAHL Plus and SPORTDiscus) up to September 2020. …”
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    Are Plantarflexor Muscle Impairments Present Among Individuals with Achilles Tendinopathy and Do They Change with Exercise? A Systematic Review with Meta-analysis
  6. 343426
    “…Due to the high prevalence of AD in DS, there is need for longitudinal imaging studies of Aβ to better characterize the natural history of Aβ accumulation, which will aid in the staging of this population for clinical trials aimed at AD treatment and prevention. METHODS: Adults with DS (N = 79; Mean age (SD) = 42.7 (7.28) years) underwent longitudinal [C-11]Pittsburgh compound B (PiB) PET. …”
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    PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer’s disease progression in Down syndrome
  7. 343427
    “…The study was registered in the German Clinical Trials Register (DRKS-ID: DRKS00012938). RESULTS: MC showed highest initial treatment costs (557.23 Euro), but the least re-treatments (6/23, 26%), while PC showed lowest initial costs (203.52 Euro) but the most re-treatments (11/20, 55%). …”
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    Long-term costs of post-restorations: 7-year practice-based results from Germany
  8. 343428
    “…Randomised controlled trials, non-randomised studies, and observational studies were eligible for inclusion. …”
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    Decentralisation, integration, and task-shifting in hepatitis C virus infection testing and treatment: a global systematic review and meta-analysis
  9. 343429
    “…CONCLUSION: Our results in conjunction with prior published data suggests that TH intra-articular joint injection in oligo JIA is superior to TA, although future controlled trials are necessary for confirmation. An effective, long lasting treatment can have a great impact on the outcome of these children.…”
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    Response to treatment with intra-articular triamcinolone hexacetonide and triamcinolone acetonide in oligo articular juvenile idiopathic arthritis
  10. 343430
    “…METHODS: A literature search for randomized controlled trials (RCTs), case–control and cohort studies published up to April 2020 was performed using PubMed and Scopus. …”
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    An updated systematic review and meta-analysis on adherence to mediterranean diet and risk of cancer
  11. 343431
    “…ELIGIBILITY CRITERIA FOR STUDY SELECTION: Randomised trials comparing drug or non-drug interventions with usual care or any other intervention targeting symptoms of depression in people with dementia. …”
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    Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis
  12. 343432
    “…Patients (pts) from two prospective trials were analyzed, provided postinduction (PInd) restaging was performed. …”
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    Kinetics of Renal Function during Induction in Newly Diagnosed Multiple Myeloma: Results of Two Prospective Studies by the German Myeloma Study Group DSMM
  13. 343433
    “…To assess the existing evidence from randomized clinical trials (RCTs) of acupuncture for PSD, we sought to draw conclusions by synthesizing RCTs. …”
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    Acupuncture for post-stroke depression: a systematic review and meta-analysis
  14. 343434
    “…The rare occurrence of Aerococcus spp. in human infections and resultant lack of randomized control trials have resulted in a significant degree of clinical uncertainty in the management of Aerococcus spp. …”
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    Aerococcus-Related Infections and their Significance: A 9-Year Retrospective Study
  15. 343435
    “…METHODS: Eight databases (MEDLINE/PubMed, Web of Science, the Cochrane database, EMBASE, CBM, CNKI, WanFang, and VIP) were searched for randomized controlled trials (RCTs) published from database inception through August 30, 2020. …”
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    Fire Acupuncture versus conventional acupuncture to treat spasticity after stroke: A systematic review and meta-analysis
  16. 343436
    “…Methods: Main databases were searched for relevant randomized controlled trials (RCTs) and observational studies reporting influencing factors of MT with FPE in AIS. …”
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    Factors Influencing Recanalization After Mechanical Thrombectomy With First-Pass Effect for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
  17. 343437
    “…ACEIs on hospitalization or mortality should be confirmed with randomized trials.…”
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    Angiotensin II receptor blocker or angiotensin-converting enzyme inhibitor use and COVID-19-related outcomes among US Veterans
  18. 343438
    “…More than half of the above tools (10, 67%) were assessed by different researchers in randomized controlled trials, while 5 tools (33%) were investigated in nonrandomized studies. …”
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    Web-Based Dietary and Physical Activity Intervention Programs for Patients With Hypertension: Scoping Review
  19. 343439
    “…In the cell, metformin stimulates AMP-activated protein kinase (AMPK) that in turn inhibits mTORC1 which integrates signals from an array of intracellular pathways to regulate cell growth. Recent clinical trials describe modest antiproliferative effects from use of neoadjuvant metformin, but no significant clinical benefit occurred when metformin was dosed at glycemic control levels in patients with advanced cancers. …”
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    Novel Metformin Analogues for Treatment of Pancreatic Cancer
  20. 343440
    “…T2DM (with HbA1c >6.5%) and all T1DM patients were excluded in alpelisib trials yet diabetes is not a formal contraindication. …”
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    Phosphoinositide 3-Kinase Inhibitor-Induced Hyperglycemia
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