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343621por Brehon, Katelyn, Niemeläinen, Riikka, Hall, Mark, Bostick, Geoff P, Brown, Cary A, Wieler, Marguerite, Gross, Douglas P“…Additional research is needed, including larger observational cohorts as well as randomized controlled trials to evaluate the effectiveness of LC rehabilitation.…”
Publicado 2022
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343622“…Consequently, we review the role of molecular imaging in the context of disease-modifying interventions to follow neurodegeneration, ensure stratification, and target engagement in clinical trials.…”
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343623por Whitworth, Pat W., Beitsch, Peter D., Patel, Rakesh, Rosen, Barry, Compagnoni, Gia, Baron, Paul L., Simmons, Rache, Brown, Eric A., Gold, Linsey, Holmes, Dennis, Smith, Linda Ann, Kinney, Michael, Grady, Ian, Clark, Patricia, Barbosa, Karen, Lyons, Samuel, Riley, Lee, Coomer, Cynara, Curcio, Lisa, Ruiz, Antonio, Khan, Sadia, MacDonald, Heather, Hughes, Kevin, Hardwick, Mary Kay, Heald, Brandie, Munro, Sandra B., Nielsen, Sarah M., Esplin, Edward D.“…Universal germline testing informs clinical decision-making and provides access to targeted treatments and clinical trials for all patients with breast cancer.…”
Publicado 2022
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343624por Hwang, Doyeon, Koo, Bon-Kwon, Zhang, Jinlong, Park, Jiesuck, Yang, Seokhun, Kim, Minsang, Yun, Jun Pil, Lee, Joo Myung, Nam, Chang-Wook, Shin, Eun-Seok, Doh, Joon-Hyung, Chen, Shao-Liang, Kakuta, Tsunekazu, Toth, Gabor G., Piroth, Zsolt, Johnson, Nils P., Pijls, Nico H. J., Hakeem, Abdul, Uretsky, Barry F., Hokama, Yohei, Tanaka, Nobuhiro, Lim, Hong-Seok, Ito, Tsuyoshi, Matsuo, Akiko, Azzalini, Lorenzo, Leesar, Massoud A., Neleman, Tara, van Mieghem, Nicolas M., Diletti, Roberto, Daemen, Joost, Collison, Damien, Collet, Carlos, De Bruyne, Bernard“…DATA SOURCES: MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were searched for relevant published articles from inception to June 18, 2022. …”
Publicado 2022
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343625por Cuenca-Fernández, Francisco, Boullosa, Daniel, López-Belmonte, Óscar, Gay, Ana, Ruiz-Navarro, Jesús Juan, Arellano, Raúl“…To be considered eligible, studies must have assessed acute short-term responses of warm-up procedures in swimmers by using randomized controlled trials or pre-post study designs. A total of 42 articles were included in this review. …”
Publicado 2022
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343626por Chalkias, Spyros, Harper, Charles, Vrbicky, Keith, Walsh, Stephen R., Essink, Brandon, Brosz, Adam, McGhee, Nichole, Tomassini, Joanne E., Chen, Xing, Chang, Ying, Sutherland, Andrea, Montefiori, David C., Girard, Bethany, Edwards, Darin K., Feng, Jing, Zhou, Honghong, Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna“…(Funded by Moderna; ClinicalTrials.gov number, NCT04927065.)…”
Publicado 2022
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343627por de Azevedo, Conceição de Maria Pedrozo e Silva, Júnior, Francisco Marcio Casarim, Neto, Eudes Alves Simões, Branco, Pedro Afonso Brito Castelo, dos Santos, Julliana Ribeiro Alves, Medeiros, Guilherme de Alencar, Marques, Sirlei Garcia, Wagner, Daniel“…Excision surgery is important for treatment due to the absence of clinical trials in the medical literature. Epidemiological surveillance studies of new cases of lacasiozis in Maranhão are important for mapping this new reservoir and developing public policies for diagnosis and treatment.…”
Publicado 2022
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343628“…The search time is from the establishment of the database to May 2022, and clinical randomized controlled trials (RCT) with advanced gastric cancer as the research object and karelizumab combined with apatinib as the research variables are collected. …”
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343629por Abusnina, Waiel, Mostafa, Mostafa Reda, Al-Abdouh, Ahmad, Radaideh, Qais, Ismayl, Mahmoud, Alam, Mahboob, Shah, Jaffer, Yousfi, Noraldeen El, Paul, Timir K., Ben-Dor, Itsik, Dahal, Khagendra“…METHODS: We searched PubMed, Cochrane CENTRAL Register and ClinicalTrials.gov (inception through July 21, 2021) for studies evaluating the outcomes of atherectomy in patients with severe LV dysfunction. …”
Publicado 2022
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343630por Reuben, Aaron, Moffitt, Terrie E, Abraham, Wickliffe C, Ambler, Antony, Elliott, Maxwell L, Hariri, Ahmad R, Harrington, Honalee, Hogan, Sean, Houts, Renate M, Ireland, David, Knodt, Annchen R, Leung, Joan, Pearson, Amber, Poulton, Richie, Purdy, Suzanne C, Ramrakha, Sandhya, Rasmussen, Line J H, Sugden, Karen, Thorne, Peter R, Williams, Benjamin, Wilson, Graham, Caspi, Avshalom“…Knowledge of a person’s risk for Alzheimer’s disease and related dementias (ADRDs) is required to triage candidates for preventive interventions, surveillance, and treatment trials. ADRD risk indexes exist for this purpose, but each includes only a subset of known risk factors. …”
Publicado 2022
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343631por O'Callaghan, Erin, Mahrer, Nicole, Belanger, Heather G, Sullivan, Scott, Lee, Christine, Gupta, Carina T, Winsberg, Mirène“…Further research and refinement, ideally via randomized controlled trials, are needed.…”
Publicado 2022
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343632por Villar, Jesús, Fernández, Cristina, González-Martín, Jesús M., Ferrando, Carlos, Añón, José M., del Saz-Ortíz, Ana M., Díaz-Lamas, Ana, Bueno-González, Ana, Fernández, Lorena, Domínguez-Berrot, Ana M., Peinado, Eduardo, Andaluz-Ojeda, David, González-Higueras, Elena, Vidal, Anxela, Fernández, M. Mar, Mora-Ordoñez, Juan M., Murcia, Isabel, Tarancón, Concepción, Merayo, Eleuterio, Pérez, Alba, Romera, Miguel A., Alba, Francisco, Pestaña, David, Rodríguez-Suárez, Pedro, Fernández, Rosa L., Steyerberg, Ewout W., Berra, Lorenzo, Slutsky, Arthur S.“…Conclusions: Subsets based on PaO(2)/FiO(2) thresholds of 150 mm Hg assessed after 24 h of moderate/severe ARDS diagnosis are clinically relevant for establishing prognosis, and are helpful for selecting adjunctive therapies for hypoxemia and for enrolling patients into therapeutic trials.…”
Publicado 2022
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343633“…METHODS: We searched the databases of PubMed, Embase, and the Cochrane Library for randomized controlled trials (RCTs) comparing catheter-directed thrombolysis (CDT) and/or pharmacomechanical thrombectomy (PMT) versus anticoagulation for acute proximal LE-DVT, published before August 2022. …”
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343634por Mushtaq, Muhammad Umair, Shahzad, Moazzam, Tariq, Ezza, Iqbal, Qamar, Chaudhary, Sibgha Gull, Zafar, Muhammad U., Anwar, Iqra, Ahmed, Nausheen, Bansal, Rajat, Singh, Anurag K., Abhyankar, Sunil H., Callander, Natalie S., Hematti, Peiman, McGuirk, Joseph P.“…METHODS: A literature search was performed on PubMed, Cochrane Library, and ClinicalTrials.gov from the inception date through April 6, 2022. …”
Publicado 2022
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343635por Luo, Lin, Wang, Shenglin, Tang, Kai, Yang, Xu, Wu, Jianli, Wang, Dan, Xu, Liqiong, Feng, Tao, Li, Dejin, Ran, Jiuju, Li, Debo, Zhang, Li, Zhao, Dan“…METHODS: PubMed, The Cochrane Library, Embase, and Web of Science databases were electronically searched to collect randomized controlled trials (RCTs) of the comparison of different dual antiplatelet regimens after coronary drug-eluting stenting from inception to September 1st, 2021. …”
Publicado 2022
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343636por Costa Clemens, Sue Ann, Fortaleza, Carlos Magno Castelo Branco, Crowe, Madeleine, Tasca, Karen Ingrid, Spadaro, André Gasparini, Souza-Neto, Jayme Augusto, Grotto, Rejane Maria Tommasini, Sider, Regina, Jimeno, Jose, Verstraeten, Thomas, Clemens, Ralf“…DISCUSSION: This observational study found the effectiveness of ChadOx1-nCoV19 to be 74.5% against COVID-19 disease of any severity, comparable to the efficacy observed in clinical trials (81.3% after dose 2), despite the dominance of the Gamma and Delta VoCs. …”
Publicado 2022
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343637por Lipschitz, Jessica M, Van Boxtel, Rachel, Torous, John, Firth, Joseph, Lebovitz, Julia G, Burdick, Katherine E, Hogan, Timothy P“…To address engagement, we must first understand what standard engagement levels are in the context of randomized controlled trials (RCTs) and how these compare with other treatments. …”
Publicado 2022
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343638por Khondker, Adree, Groff, Michael, Nunes, Sophia, Sun, Carolyn, Jawa, Natasha, Lee, Jasmine, Cockovski, Vedran, Hejri-Rad, Yasmine, Chanchlani, Rahul, Fleming, Adam, Garg, Amit, Jeyakumar, Nivethika, Kitchlu, Abhijat, Lebel, Asaf, McArthur, Eric, Mertens, Luc, Nathan, Paul, Parekh, Rulan, Patel, Serina, Pole, Jason, Ramphal, Raveena, Schechter, Tal, Silva, Mariana, Silver, Samuel, Sung, Lillian, Wald, Ron, Gibson, Paul, Pearl, Rachel, Wheaton, Laura, Wong, Peter, Kim, Kirby, Zappitelli, Michael“…Our work will address international priorities to improve CCS health, provide the evidence of new disease burden and practice gaps to improve CCS guidelines, implement and test revised guidelines, plan trials to reduce CKD and hypertension, and improve long-term CCS health.…”
Publicado 2022
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343639por Andre, Clarissa, Aronne, Louis, D’Angelo, Debra, Shukla, Alpana, Tchang, Beverly, Weintraub, Michael“…The mean number of AOMs trialed throughout the duration of the study was 4.2. …”
Publicado 2022
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343640por Patel, Mayank, Jha, Abhisek, Ling, Alexander, Chen, Clara C, Millo, Corina, Talvacchio, Sara, Ezemobi, Josephine, Kailah, Charles, David, Taïeb, Carrasquillo, Jorge A, Pacak, Karel“…CONCLUSION: The study was performed in a small patient set with VHL-related PHEO showed MRI, with the highest detection percent followed by (18)F-FDG PET/CT. More trials with a larger patient set are needed to support the statistical relevance as it was not seen in this study. …”
Publicado 2022
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