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  1. 343901
    “…BACKGROUND: Early randomized controlled trials have demonstrated the benefits of tight glucose control. …”
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    Glycemic control in critically ill patients with or without diabetes
  2. 343902
    “…There is a need for a strong methodology for the SR of randomized controlled trials to explore their effectiveness and the entire cascade of implementation outcomes.…”
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    Implementation Strategies for Knowledge Products in Primary Health Care: Systematic Review of Systematic Reviews
  3. 343903
    “…Randomized controlled trials reporting changes in leg press or knee extension one repetition maximum and femur/hip or lumbar spine BMD following progressive resistance training in men and/or women ≥ 65 years of age were included. …”
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    Progressive Resistance Training for Concomitant Increases in Muscle Strength and Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis
  4. 343904
    “…Given the demonstrated efficacy of 3MDR in recently published randomized control trials, there is both an interest in and a need to adapt the intervention to other populations affected by trauma and to improve accessibility to the treatment. …”
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    The Redesign and Validation of Multimodal Motion-Assisted Memory Desensitization and Reconsolidation Hardware and Software: Mixed Methods, Modified Delphi–Based Validation Study
  5. 343905
    “…METHODS: We searched PubMed, EMBASE, Cochrane Central Register of Controlled Trials, the Chinese Biomedicine Literature Database, Chinese National Knowledge Infrastructure, Wanfang Database, and the VIP Database for diagnostic studies on ML algorithms’ accuracy in predicting kidney disease prognosis, from the establishment of these databases until October 2020. …”
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    Machine learning algorithms’ accuracy in predicting kidney disease progression: a systematic review and meta-analysis
  6. 343906
    “…Family discovery is of great relevance for the region, as new initiatives are underway to extend clinical trials and observational studies to families living with DIAD.…”
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    Discovery and validation of dominantly inherited Alzheimer’s disease mutations in populations from Latin America
  7. 343907
    “…Coordinating care for patients with MBC can be challenging given the various treatment options, available clinical trials, and frequent need for ancillary services. …”
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    Adapting and Developing an Academic and Community Practice Collaborative Care Model for Metastatic Breast Cancer Care (Project ADAPT): Protocol for an Implementation Science–Based Study
  8. 343908
    “…These indirect comparisons should be interpreted with caution while awaiting confirmatory data from prospective randomized trials.…”
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    Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows
  9. 343909
    “…CONCLUSIONS: (1) Despite the number of prescriptions was reduced because of the pandemic, the lipid control was not affected. (2) Half of the patients treated with PSCK9i is due to statins intolerance and the 86% is for secondary prevention. (2) The reduction results were similar to pivotal clinical trials. Despite this, 39% of the total of the patients and 60% of patients with dual teraphy did not reach the goal of ESC/EAS guidelines (< 55 mg/dl and/or reduction > 50%). …”
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    Impact of the COVID-19 pandemic in the lipid control of the patients that start PCSK9 inhibitors
  10. 343910
    “…They included three prospective randomized-controlled trials, 13 retrospective cohort studies, two prospective cohort studies. …”
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    Irrigation techniques used in spine surgery for surgical site infection prophylaxis: a systematic review and meta-analysis
  11. 343911
    “…A systematic review was conducted when numerous randomized controlled trials were available. Results were presented and discussed at an international consensus meeting at the World Association of photobiomoduLation Therapy (WALT) meeting in 2018 that included world expert oncologists, radiation oncologists, oral oncologists, and oral medicine professionals, physicists, engineers, and oncology researchers. …”
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    Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022
  12. 343912
    “…METHODS: Plasma metabolomic profiles were analyzed using liquid chromatography-tandem mass spectrometry in the WHI-OS (Women’s Health Initiative-Observational Study; 138 Black and 696 White women), WHI-HT trials (WHI-Hormone Therapy; 156 Black and 1138 White women), MESA (Multi-Ethnic Study of Atherosclerosis; 114 Black and 219 White women), JHS (Jackson Heart Study; 1465 Black women with 107 incident CHD cases), and NHS (Nurses’ Health Study; 2506 White women with 136 incident CHD cases). …”
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    Differences in Metabolomic Profiles Between Black and White Women and Risk of Coronary Heart Disease: an Observational Study of Women From Four US Cohorts
  13. 343913
    “…Due to the low quality of evidence, conducting more randomized controlled trials with rigorous design is suggested. Prospero registration This systematic review has been registered in Prospero (ID: CRD42021277213).…”
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    The effect of cognitive behavior therapy on anxiety and depression during COVID-19 pandemic: a systematic review and meta-analysis
  14. 343914
    “…However, these are rarely used in clinical trials of interventions in axial spondyloarthritis (axSpA). …”
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    Generating EQ-5D-5L health utility scores from BASDAI and BASFI: a mapping study in patients with axial spondyloarthritis using longitudinal UK registry data
  15. 343915
    “…Randomized controlled trials are needed to establish the effect of chiropractic care on opioid use for chronic spinal pain. …”
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    The association between chiropractic integration in an Ontario community health centre and continued prescription opioid use for chronic non-cancer spinal pain: a sequential explanatory mixed methods study
  16. 343916
    “…METHODS: Systematic literature searches were conducted of PubMed, Cochrane Library, Web of Science, Medline and Embase covering January 1, 2000 to December 30, 2021. Randomized control trials (RCTs) comparing finerenone, SGLT-2i and GLP-1 RA in diabetics with CKD were selected. …”
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    Network meta-analysis on the effects of finerenone versus SGLT2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in patients with type 2 diabetes mellitus and chronic kidney disease
  17. 343917
    “…These results provide a potentially superior treatment strategy and require verification in prospective clinical trials.…”
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    The efficacy and safety of immune checkpoint inhibitors combined with chemotherapy or anti-angiogenic therapy as a second-line or later treatment option for advanced non-small cell lung cancer: a retrospective comparative cohort study
  18. 343918
    por Wang, Weihao, Wei, Ran, Pan, Qi, Guo, Lixin
    Publicado 2022
    “…RESULTS: Ten randomized controlled trials involving 694 patients were identified. TRE significantly reduced systolic blood pressure (SBP) (mean difference = −4.15; 95% CI: −6.73, −2.30; P < 0.0001), but had no significant effect on diastolic blood pressure (DBP) (mean difference = −2.06; 95% CI: −4.16, 0.02; P = 0.053) and no beneficial effect on heart rate (mean difference = 0.36; 95% CI: −2.83, 3.54; P = 0.0825). …”
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    Beneficial effect of time-restricted eating on blood pressure: a systematic meta-analysis and meta-regression analysis
  19. 343919
    “…LAT1 has been proposed as a potential target for cancer treatment—its inhibitor, JPH203, is currently in clinical trials and targets biliary tract cancer (BTC). Here, we revealed to what extent LAT1 inhibitor affects intracellular amino acid content and what kind of cellular signals are directly triggered by LAT1 inhibition. …”
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    Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1
  20. 343920
    “…Postural sway together with EEG (32-channels) were recorded during trials of standing with and without a concurrent verbalized serial subtraction dual-task. …”
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    Brain activity during dual-task standing in older adults
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