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  1. 343981
    “…HTN was diagnosed in her late twenties. She was previously trialed on eight different classes of antihypertensive medications excluding mineralocorticoid antagonists or potassium-sparing diuretics but HTN remained uncontrolled. …”
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    FRI190 Catching A Chimera: A Case Of Suspected Glucocorticoid Remediable Aldosteronism
  2. 343982
    “…Eligible articles were randomized controlled trials and cohort studies assessing the effect of an eHealth intervention for pharmacotherapy management compared with usual care on pharmacotherapy management or clinical outcomes in patients with asthma or COPD, CVD, or diabetes. …”
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    The Use of eHealth for Pharmacotherapy Management With Patients With Respiratory Disease, Cardiovascular Disease, or Diabetes: Scoping Review
  3. 343983
    por Shin, Dong-Yeop
    Publicado 2023
    “…Decitabine, a hypomethylating agent, is known to be relatively effective in patients with AML. Numerous trials are ongoing to investigate the effects of novel drugs combined with hypomethylating agents, TP53-targeting agents or immunologic agents. …”
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    TP53 Mutation in Acute Myeloid Leukemia: An Old Foe Revisited
  4. 343984
    “…CONCLUSIONS: This study will provide in-depth insight into temporally and spatially precise trajectories of patients with cancer that will provide a novel digital health approach and will inform the design of future interventional clinical trials in oncology. Our findings will allow a better understanding of the potential clinical value of passively generated smartphone sensor data (digital phenotyping) for continuous and real-time monitoring of patients with cancer for treatment side effects, cancer complications, functional status, and patient-reported outcomes as well as prediction of disease progression or trajectories. …”
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    Digital Phenotyping for Monitoring and Disease Trajectory Prediction of Patients With Cancer: Protocol for a Prospective Observational Cohort Study
  5. 343985
    “…Data were gathered from 2 completed and 4 ongoing randomized controlled trials, 11 pilot studies, and over 1000 co-design sessions using MOST. …”
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    Developing a Theory of Change for a Digital Youth Mental Health Service (Moderated Online Social Therapy): Mixed Methods Knowledge Synthesis Study
  6. 343986
    “…Materials and Methods: Eligible randomized controlled trials (RCTs) were selected after a search in CENTRAL, Scopus, and PubMed. …”
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    Effectiveness of Lifestyle Interventions during Pregnancy on Preventing Gestational Diabetes Mellitus in High-Risk Women: A Systematic Review and Meta-Analyses of Published RCTs
  7. 343987
    “…VYD222 is a re-engineered version of adintrevimab, an Fc-modified mAb that has a robust safety data package and demonstrated clinically meaningful results in Phase 2/3 clinical trials for both treatment and prevention of COVID-19 (NCT04805671, NCT04859517). …”
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    1363. Preliminary Safety Results from a Phase 1 First in Human Study of VYD222: an Extended Half-Life Monoclonal Antibody (mAb) in Development for COVID-19 Prevention
  8. 343988
    “…BACKGROUND: The efficacy of the BNT162b2 vaccine in pediatrics was assessed by randomized trials before the Omicron variant’s emergence. The long-term durability of vaccine protection in this population during the Omicron period remains limited. …”
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    Real-world Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents
  9. 343989
    “…Data from randomized controlled trials (RCTs) and non‐RCTs were presented and synthesized separately. …”
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    Friendly visiting by a volunteer for reducing loneliness or social isolation in older adults: A systematic review
  10. 343990
    “…These results may have important implications and this pilot study may lead to a series of trials that shed light on the mechanisms of ischaemia-reperfusion injury, including potential points of therapeutic intervention for pathophysiological conditions.…”
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    Mild episodes of tourniquet-induced forearm ischaemia-reperfusion injury results in leukocyte activation and changes in inflammatory and coagulation markers
  11. 343991
    “…The recommended dose for use in phase II clinical trials is topotecan 1.0 mg m-2 on days 1-5 and etoposide 40 mg bid on days 6-12 every 4 weeks.…”
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    Phase I and pharmacological study of sequential intravenous topotecan and oral etoposide.
  12. 343992
    por Binks, Martin, van Mierlo, Trevor
    Publicado 2010
    “…However, most studies do not reflect the more naturalistic and common ad libitum, or freely at will, use of the Internet. Randomized clinical trials, for example, typically include at least some direct contact with participants and often have restrictive selection criteria. …”
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    Utilization Patterns and User Characteristics of an Ad Libitum Internet Weight Loss Program
  13. 343993
    “…The antigen-directed and cancer-specific (124)I-radiolabled anti-TAG-72 monoclonal antibody conjugate, (124)I-HuCC49deltaC(H)2, holds future potential for use in human clinical trials for preoperative, intraoperative, and postoperative PET-based imaging strategies, including fused-modality PET-based imaging platforms.…”
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    (124)I-HuCC49deltaC(H)2 for TAG-72 antigen-directed positron emission tomography (PET) imaging of LS174T colon adenocarcinoma tumor implants in xenograft mice: preliminary results
  14. 343994
    “…To complete the preclinical development and meet the regulatory requirements before initiating human trials, the anti-parasitic properties and the pharmacokinetic, metabolic and toxicological profile of fexinidazole have been assessed. …”
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    Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness
  15. 343995
    “…The preferred types of clinical studies for these evaluations are randomized controlled trials. However, all institutions do allow for other types of evidence (e. g. expert opinion) when no other study types of a higher evidence level are available. …”
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    Procedures and Criteria for the regulation of innovative non-medicinal technologies into the benefit catalogue of solidly financed health care insurances
  16. 343996
    “…The medical analysis was initially based on systematic reviews of randomized controlled trials (RCT) and was followed by the evaluation of RCT with use of current optimal medical therapy. …”
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    Percutaneous coronary intervention with optimal medical therapy vs. optimal medical therapy alone for patients with stable angina pectoris
  17. 343997
    “…Medians for both arms show a gradual decrease and significant difference of the number of successful trials with increasing condition difficulty (F(2;60 )= 44.623; p < 0.01; η(2 )= 0.623) but no significant difference between paretic and non-paretic arm (F(1;60 )= 3.768; p = 0.057; η(2 )= 0.065). …”
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    Validation of a mechanism to balance exercise difficulty in robot-assisted upper-extremity rehabilitation after stroke
  18. 343998
    “…BACKGROUND: In randomized controlled trials, participants cannot choose their preferred intervention delivery mode and thus might refuse to participate or not engage fully if assigned to a nonpreferred group. …”
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    Do Participants’ Preferences for Mode of Delivery (Text, Video, or Both) Influence the Effectiveness of a Web-Based Physical Activity Intervention?
  19. 343999
    “…Randomised controlled trials (RCT), where applicable also containing relevant health economic evaluations and publications addressing the ethical, social and legal aspects of using bone graft substitutes for fracture treatment were included in the analysis. …”
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    Bone graft substitutes for the treatment of traumatic fractures of the extremities
  20. 344000
    “…Lessons from mHealth trials and studies were summarized, focusing on low- and middle-income countries and community health workers. …”
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    Mobile Health (mHealth) Approaches and Lessons for Increased Performance and Retention of Community Health Workers in Low- and Middle-Income Countries: A Review
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