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344001por Lamberg-Allardt, Christel, Brustad, Magritt, Meyer, Haakon E., Steingrimsdottir, Laufey“…In the first search, we focused only on systematic literature reviews (SLRs) and in the second on SLRs and randomized control trials (RCTs) published after March 2009. Furthermore, we used snowballing for SLRs and IRCTs published between February 2011 and May 2012. …”
Publicado 2013
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344002por Banerjee, Anjan K., Okun, Sally, Edwards, I. Ralph, Wicks, Paul, Smith, Meredith Y., Mayall, Stephen J., Flamion, Bruno, Cleeland, Charles, Basch, Ethan“…This framework considers populations that are prespecified (such as those in clinical trials, prospective observational studies and some registries) and non-prespecified populations (such as those in claims databases, PRO-enabled online patient networks, and social websites in general). …”
Publicado 2013
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344003por Zimmerman, Y., Eijkemans, M.J.C., Coelingh Bennink, H.J.T., Blankenstein, M.A., Fauser, B.C.J.M.“…METHODS: A review of the literature was performed using database searches (MEDLINE, EMBASE and the Cochrane Central Register of Clinical Trials) and all publications (from inception date until July 2012) investigating the effect of COCs on androgen levels in healthy women were considered eligible for selection. …”
Publicado 2014
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344004por Ou, Sai-Hong Ignatius, Soo, Ross A., Kubo, Akihito, Kawaguchi, Tomoya, Ahn, Myung-Ju“…Many pharmaceutical companies are now using the Food and Drug Administration (FDA)-approved ALK FISH assay to enroll patients onto trials for their own respective ALK inhibitors. In essence they are “piggybacking” on the FDA-approved ALK FISH assay without having to pay for the development of a CDx, nor screening for ALK-rearranged NSCLC patients in the protocols because screening for ALK rearrangement is now the standard of care in NSCLC after the approval of crizotinib. …”
Publicado 2014
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344005por Walsh, Joanne, Jenkins, Rosalind E., Wong, Michael, Olayanju, Adedamola, Powell, Helen, Copple, Ian, O’Neill, Paul M., Goldring, Christopher E.P., Kitteringham, Neil R., Park, B. Kevin“…For example, CDDO-me (bardoxolone methyl) was investigated in clinical trials for the treatment of acute kidney disease, and dimethyl fumarate, recently approved for reducing relapse rate in multiple sclerosis, is a potent Nrf2 inducer. …”
Publicado 2014
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344006por Dittmann, Ralf W., Cardo, Esther, Nagy, Peter, Anderson, Colleen S., Adeyi, Ben, Caballero, Beatriz, Hodgkins, Paul, Civil, Richard, Coghill, David R.“…The primary efficacy and safety outcomes of the study, SPD489-317 (ClinicalTrials.gov NCT01106430), have been published previously. …”
Publicado 2014
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344007“…The study provides reason for systematic reviews of assisted hatching trials to take the method of assisted hatching into consideration and not combine the results of zona thinning and zona opening procedures. …”
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344008por Salaffi, Fausto, Ciapetti, Alessandro, Carotti, Marina, Gasparini, Stefania, Citera, Gustavo, Gutierrez, Marwin“…SASDAS is easy to calculate and, therefore, appear suitable for clinical decision making, epidemiologic research, and clinical trials. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12955-014-0129-9) contains supplementary material, which is available to authorized users.…”
Publicado 2014
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344009por van Baarsen, Lisa GM, Lebre, Maria C, van der Coelen, Dennis, Aarrass, Saïda, Tang, Man W, Ramwadhdoebe, Tamara H, Gerlag, Daniëlle M, Tak, Paul P“…Accordingly, clinical trials aimed at blocking IL-17 have been initiated, but clinical results between patients and across different diseases have been highly variable. …”
Publicado 2014
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344010por Singh, Dave, Pujol, Helena, Ribera, Anna, Seoane, Beatriz, Massana, Eric, Astbury, Carol, Ruiz, Sandrine, de Miquel, Gonzalo“…METHODS: This was a Phase II, randomized, double-blind, double-dummy, crossover, placebo-controlled, dose-ranging study (ClinicalTrials.gov NCT01425801) in 62 patients with mild-to-moderate asthma who were also receiving an ICS. …”
Publicado 2014
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344011“…We compared the grasp kinematics from trials with and without terminal tactile feedback to a real-time-pantomimed grasping task (one without tactile feedback) in which participants visualized a copy of the visible target as instructed in our laboratory in the past. …”
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344012por Shinto, Ajit S., Kamaleshwaran, K. K., Chakraborty, Sudipta, Vyshakh, K., Thirumalaisamy, S. G., Karthik, S., Nagaprabhu, V. N., Vimalnath, K. V., Das, Tapas, Banerjee, Sharmila“…More elaborate and controlled clinical trials are necessary to evaluate the therapeutic efficacy and safety of the agent compared with the treatment with other radionuclides and glucocorticosteroids.…”
Publicado 2015
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344013por Boelaert, Marleen, Verdonck, Kristien, Menten, Joris, Sunyoto, Temmy, van Griensven, Johan, Chappuis, Francois, Rijal, Suman“…SEARCH METHODS: We searched MEDLINE, EMBASE, LILACS, CIDG SR, CENTRAL, SCI‐expanded, Medion, Arif, CCT, and the WHO trials register on 3 December 2013, without applying language or date limits. …”
Publicado 2014
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344014The Effect of an Acetabular Labral Tear, Repair, Resection, and Reconstruction on the Hip Fluid Sealpor Nepple, Jeffrey J., Campbell, Kevin J., Wijdicks, Coen A., Jansson, Kyle, Dornan, Grant, LaPrade, Robert F., Philippon, Marc J.“…Additionally, the distractive strength of the hip fluid seal was recorded after each loading cycle. Three loading trials were performed for each labral condition. Specimens were randomized to looped or through type labral suture repairs within matched hips. …”
Publicado 2014
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344015por Chahal, Jaskarndip, Thiel, Geoffrey S. Van, Mather, Richard C., Lee, Simon, Salata, Michael Jonathan, Nho, Shane Jay“…Our findings will allow researchers to determine if interventions related to FAI are meaningful to patients at the individual level across various domains and will also be useful for power calculations in future randomized trials related to hip arthroscopy and the treatment of FAI.…”
Publicado 2014
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344016por Borgonovo, Tamara, Solarewicz, Maria Marlene, Vaz, Isadora May, Daga, Debora, Rebelatto, Carmen Lúcia Kuniyoshi, Senegaglia, Alexandra Cristina, Ribeiro, Enilze, Cavalli, Iglenir João, Brofman, Paulo Slud“…Therefore, genomic integrity of stem cells should be monitored carefully for the use in basic research and clinical trials, including karyotype analysis to confirm the absence of genetic instability. …”
Publicado 2015
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344017por Suwanthawornkul, Thanthima, Anothaisintawee, Thunyarat, Sobhonslidsuk, Abhasnee, Thakkinstian, Ammarin, Teerawattananon, Yot“…However, there has been no evidence from randomized controlled trials (RCTs) that directly compare the efficacy among the different regimens of DAAs. …”
Publicado 2015
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344018“…Subsequently, meta-analyses were conducted based on standardized mean differences (SMD) from randomized controlled trials (RCTs) that reported knowledge or decisional conflict. …”
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344019“…Their homologous and non-homologous use as autologous and allogeneic cells for therapeutic purposes is currently being assessed in preclinical animal models of pelvic organ prolapse and phase I/II clinical trials for cardiac failure. eMSCs and stromal fibroblasts also exhibit non-stem cell-associated immunomodulatory and anti-inflammatory properties, further emphasizing their desirable properties for cell-based therapies. …”
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344020por Kahana, Shoshana Y., Jenkins, Richard A., Bruce, Douglas, Fernandez, Maria I., Hightow-Weidman, Lisa B., Bauermeister, Jose A.“…METHODS: The sample included 1891 adolescents and young adults living with HIV (27.8% perinatally infected; 72.2% behaviorally infected) who were linked to care through 20 Adolescent Medicine Trials Network for HIV/AIDS Interventions Units. All completed audio computer–assisted self-interview surveys. …”
Publicado 2016
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