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  1. 344161
    “…(Research Grant or Support)Paratek (Speaker’s Bureau)Summit (Other Financial or Material Support, Research funding (clinical trials))…”
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    112. Impact of Respiratory Viral PCR Panels (RVP) and Serum Procalcitonin (PCT) on Antibiotic Days of Therapy (DOT) in Patients Admitted with Lower Respiratory Tract Infections (LRTI)
  2. 344162
    “…Randomized-controlled trials of antifungal prophylaxis in high-risk pts are needed. …”
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    1105. The Burden of Infections Prior to Chimeric Antigen Receptor (CAR) Modified T-cell Therapy Predicts Post-CAR T-cell Infectious Complications
  3. 344163
    “…(Research Grant or Support)Paratek (Speaker’s Bureau)Summit (Other Financial or Material Support, Research funding (clinical trials))…”
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    1309. Imipenem/Cilastatin/Relebactam (I/R) Alone and in Combination against Pseudomonas aeruginosa (PSA) in the In Vitro Pharmacodynamic Model
  4. 344164
    “…These results have important implications for new non-β-lactam β-lactamase inhibitors (nacubactam, zidebactam) with structural similarities to AVI and known intrinsic antibacterial activity that have recently completed Phase I trials in combination with β-lactam drugs and are likely to play an important future role in CRE treatment. …”
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    1447. Emergence of Avibactam Resistance in Multidrug-Resistant Enterobacteriaceae
  5. 344165
    “…Methods This is a post-hoc analysis of clinical data prospectively collected of the Pre-AndroCoV and AndroCov Trials, which resulted in scorings for the clinical diagnosis of COVID-19 based on the likelihood of presenting with actual COVID-19 according to the number of symptoms, presence of anosmia, and known positive household contact. …”
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    The AndroCoV Clinical Scoring for COVID-19 Diagnosis: A Prompt, Feasible, Costless, and Highly Sensitive Diagnostic Tool for COVID-19 Based on a 1757-Patient Cohort
  6. 344166
    “…These findings are important considerations for the design of clinical trials, and might improve our understanding of factors associated with faster tau aggregation and spread.…”
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    The accumulation rate of tau aggregates is higher in females and younger amyloid-positive subjects
  7. 344167
    por Patel, Neha A.
    Publicado 2020
    “…Various treatment regimens including interferon, antivirals, and hydroxychloroquine therapies have been trialed on the pediatric population but there are currently no studies showing efficacy of one regimen over the other. …”
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    Pediatric COVID-19: Systematic review of the literature
  8. 344168
    “…None of the studies were randomized controlled trials; most had a quasi-experimental design, for example, comparative experimental evaluation studies nested on other ongoing cross-sectional surveys. …”
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    Data Quality and Cost-effectiveness Analyses of Electronic and Paper-Based Interviewer-Administered Public Health Surveys: Systematic Review
  9. 344169
    “…METHODS: This post-hoc analysis used data from three randomised, double-blind, placebo-controlled phase III belimumab trials: BLISS-52 (BEL110752; NCT00424476), BLISS-76 (BEL110751; NCT00410384) and BLISS-SC (BEL112341; NCT01484496). …”
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    Efficacy of belimumab in two serologically distinct high disease activity subgroups of patients with systemic lupus erythematosus: post-hoc analysis of data from the phase III programme
  10. 344170
    “…We too experienced many problems while using it in our routine clinical practice and in clinical trials. For instance, the Naranjo scale is non-specific and shows a bias toward implicating the drug as the causal factor for AEs. …”
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    Validation of a novel causality assessment scale for adverse events in non-small cell lung carcinoma patients treated with platinum and pemetrexed doublet chemotherapy
  11. 344171
    “…CONCLUSIONS: These studies, which closely followed Food and Drug Administration Guidance for Industry on patient-reported outcome measures, support use of the IDSIQ as a fit-for-purpose measure for deriving valid and reliable endpoints in insomnia clinical research trials and real-world studies. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40271-020-00474-z) contains supplementary material, which is available to authorized users.…”
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    Development and Validation of the Insomnia Daytime Symptoms and Impacts Questionnaire (IDSIQ)
  12. 344172
    “…BACKGROUND: For the clinical care of patients with well-established diseases, randomized trials, literature, and research are supplemented with clinical judgment to understand disease prognosis and inform treatment choices. …”
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    Learning From Past Respiratory Infections to Predict COVID-19 Outcomes: Retrospective Study
  13. 344173
    “…The widespread acceptance of a biomarker classification scheme for the Alzheimer’s disease continuum has ignited interest in more affordable and accessible approaches to detect Alzheimer’s disease β-amyloid pathology, a process that often slows down the recruitment into, and adds to the cost of, clinical trials. Recently, there has been considerable excitement concerning the value of blood biomarkers. …”
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    Detection of β-amyloid positivity in Alzheimer’s Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers
  14. 344174
    “…Only randomized controlled trials (RCTs) comparing extra-short implants and longer implants in the same study reporting survival rate with an observation period at least 1 year were selected. …”
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    A meta-analysis indicating extra-short implants (≤ 6 mm) as an alternative to longer implants (≥ 8 mm) with bone augmentation
  15. 344175
    “…As data accumulate from trials and implementation studies, such findings can be incorporated into the model to better inform on the full consequences of policy alternatives. …”
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    The potential role of long-acting injectable cabotegravir–rilpivirine in the treatment of HIV in sub-Saharan Africa: a modelling analysis
  16. 344176
    “…Targeted therapies for BRAF and PD-L1 have been used for melanoma and there are ongoing clinical trials for use of PD-L1 inhibitors in PTC but its utility is uncertain. …”
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    Molecular Genetics in a Cohort of Patients With Concurrent PTC and Melanoma
  17. 344177
    “…Discussion: Several clinical trials have demonstrated that the combination of AB plus ADT prolongs overall survival in DCSPC. …”
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    Late Onset of Abiraterone Severe Hypokalemia Due to Unsuspected ACTH-Secreting NEC
  18. 344178
    por Marenych, Nadiia, Gilden, Janice L
    Publicado 2021
    “…Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials. Diabetes Care 2018 Dec; 41(12): 2560–2569.…”
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    A Case Report of Euglycemic Diabetic Ketoacidosis in the Setting of Keto Diet and SGLT-2 Inhibitors
  19. 344179
    “…These results suggest that patients may need to reach a stimulated TSH ≥30 mIU/L stimulated TSH threshold to be treated. Randomized trials are needed to confirm these findings.…”
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    Effectiveness of Different Thyroid Stimulating Hormone Thresholds for Thyroid Hormone Withdrawal - Aided Radioiodine Ablation in Patients With Differentiated Thyroid Cancer: A Systematic Review and Meta - Analysis
  20. 344180
    “…The association between radioactive iodine (RAI) therapy and reduced fertility has remained controversial, in part because no large-scale randomized clinical trials or prospective studies have been done in this regard. …”
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    Birth Rates After Radioactive Iodine Treatment for Well Differentiated Cancer in Female Patients With Reproductive Potentials: A Meta- Analysis
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