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344261por Nabizadeh, Fardin, Pirahesh, Kasra, Rafiei, Nazanin, Afrashteh, Fatemeh, Ahmadabad, Mona Asghari, Zabeti, Aram, Mirmosayyeb, Omid“…We included cohort studies, clinical trials, case–control studies, and case series that investigated the efficacy or safety of AHSCT in patients with MS. …”
Publicado 2022
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344262por Paul, Rachel, Raghuraman, Nandini, Carter, Ebony B., Odibo, Anthony O., Kelly, Jeannie C., Foeller, Megan E., Perez, Marta J.“…BACKGROUND: Clinical trials of the messenger RNA COVID-19 vaccines excluded individuals with active reproductive needs (attempting to conceive, currently pregnant, and/or lactating). …”
Publicado 2022
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344263por Khan, Jaffar, Ullah, Asad, Waheed, Abdul, Karki, Nabin Raj, Adhikari, Nawaraj, Vemavarapu, Lakshmi, Belakhlef, Sami, Bendjemil, Samy Malik, Mehdizadeh Seraj, Siamak, Sidhwa, Feroze, Ghleilib, Intisar, Foroutan, Shahin, Blakely, Andrew M., Del Rivero, Jaydira, Karim, Nagla Abdel, Vail, Eric, Heneidi, Saleh, Mesa, Hector“…GIST patients would benefit from enrollment in large clinical trials to establish better therapy guidelines for unresectable, treatment-refractory, and recurrent tumors.…”
Publicado 2022
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344264por Obayashi, Yuki, Watanabe, Hirotoshi, Morimoto, Takeshi, Yamamoto, Ko, Natsuaki, Masahiro, Domei, Takenori, Yamaji, Kyohei, Suwa, Satoru, Isawa, Tsuyoshi, Watanabe, Hiroki, Yoshida, Ruka, Sakamoto, Hiroki, Akao, Masaharu, Hata, Yoshiki, Morishima, Itsuro, Tokuyama, Hideo, Yagi, Masahiro, Suzuki, Hiroshi, Wakabayashi, Kohei, Suematsu, Nobuhiro, Inada, Tsukasa, Tamura, Toshihiro, Okayama, Hideki, Abe, Mitsuru, Kawai, Kazuya, Nakao, Koichi, Ando, Kenji, Tanabe, Kengo, Ikari, Yuji, Morino, Yoshihiro, Kadota, Kazushige, Furukawa, Yutaka, Nakagawa, Yoshihisa, Kimura, Takeshi“…BACKGROUND: The benefit of clopidogrel monotherapy after 1-month dual antiplatelet therapy (DAPT) compared with 12-month DAPT with aspirin and clopidogrel was demonstrated in the STOPDAPT-2 (Short and Optimal Duration of Dual Antiplatelet Therapy After Everolimus-Eluting Cobalt-Chromium Stent-2), but not in the STOPDAPT-2 acute coronary syndrome (ACS); however, both trials were underpowered based on the actual event rates. …”
Publicado 2022
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344265por Pedamallu, Havisha, Ehrhardt, Matthew J, Maki, Julia, Carcone, April Idalski, Hudson, Melissa M, Waters, Erika A“…Of the 34 studies, 30 (88%) were randomized controlled trials reporting behavioral and health-related outcomes, 23 of which reported statistically significant improvements in targeted behaviors with TAMI use. …”
Publicado 2022
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344266por Puthanakit, Thanyawee, Nantanee, Rapisa, Jaru-Ampornpan, Peera, Chantasrisawad, Napaporn, Sophonphan, Jiratchaya, Meepuksom, Thutsanun, Jupimai, Thidarat, Sodsai, Pimpayao, Anugulruengkitt, Suvaporn, Hirankarn, Nattiya“…After 5-month interval, booster with BNT162b2 induced high neutralizing titer against Omicron strain. Thai Clinical Trials Registry (thaiclinicaltrials.org): TCTR20210923012.…”
Publicado 2022
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344267por Antonelli, Mary T., Cox, John S., Saphirak, Cassandra, Gurwitz, Jerry H., Singh, Sonal, Mazor, Kathleen M.“…CONCLUSION: Mailing educational materials about potentially inappropriate medications to community-dwelling patients with ADRD may promote deprescribing conversations. Ongoing pragmatic trials will determine whether such interventions stimulate deprescribing conversations and achieve reductions in prescribing of inappropriate medications. …”
Publicado 2022
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344268“…RESULTS: A total of 43 articles were identified and categorized into randomized controlled trials (RCT), observational or interventional studies. …”
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344269por Della Vecchia, Claire, Leroy, Tanguy, Bauquier, Charlotte, Pannard, Myriam, Sarradon-Eck, Aline, Darmon, David, Dufour, Jean-Charles, Preau, Marie“…In multivariate analysis, involvement in continued education programs (odds ratio [OR] 6.17, 95% CI 1.52-28.72), a better patient base command of the French language (OR 1.45, 95% CI 1.13-1.88), GP-perceived benefits of mHealth apps and devices for both patients and their medical practice and GP-perceived drivers for mHealth apps and device implementation in their medical practice (OR 1.04, 95% CI 1.01-1.07), and validation of mHealth apps and devices through randomized clinical trials (OR 1.02, 95% CI 1.00-1.04) were all associated with GPs’ willingness to prescribe mHealth apps and devices. …”
Publicado 2022
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344270“…Drug history included: Phototherapy without response (2007), then cyclosporine 100mg BD for six weeks which stopped due to severe mood changes. Unsuccessful trials of 20 mg oral methotrexate once weekly because of elevated liver enzymes, subcutaneous form causing significant neurapraxia, adalimumab (2010-2013) stopped due to secondary failure, ustekinumab (2013-2014) stopped after three injections (primary failure), Infliximab (2014-2015) stopped due to throat swelling during transfusion, apremilast 30mg BD stopped due to complete inefficacy. …”
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344271por Shan, Zack Y., Mohamed, Abdalla Z., Andersen, Thu, Rendall, Shae, Kwiatek, Richard A., Fante, Peter Del, Calhoun, Vince D., Bhuta, Sandeep, Lagopoulos, Jim“…ETHICS AND STUDY REGISTRY: This study was reviewed and approved by University of the Sunshine Coast University Ethics committee (A191288) and has been registered with The Australian New Zealand Clinical Trials Registry (ACTRN12622001095752). DISSEMINATION OF RESULTS: The results will be disseminated through peer reviewed scientific manuscripts and conferences and to patients through social media and active engagement with ME/CFS associations.…”
Publicado 2022
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344272“…The small sample size and unclear impacts of COVID-19 on the study design should be considered when interpreting the results. Controlled trials with larger sample sizes for evaluating SMS text messaging interventions aimed to support caregivers of children undergoing tonsillectomy surgery are warranted.…”
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344273por Martinez-Millana, Antonio, Saez-Saez, Aida, Tornero-Costa, Roberto, Azzopardi-Muscat, Natasha, Traver, Vicente, Novillo-Ortiz, David“…The analyzed papers show results only in laboratory and testing scenarios and not in clinical trials nor case studies, limiting the supporting evidence to transfer artificial intelligence to actual care delivery.…”
Publicado 2022
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344274por Kirsebom, Bjørn Eivind, Richter, Grit, Nordengen, Kaja, Aarsland, Dag, Bråthen, Geir, Tijms, Betty M, Visser, Pieter Jelle, Nilsson, Johanna, Selnes, Per, Kramberger, Milica G, Winblad, Bengt, Waterloo, Knut, Gísladóttir, Berglind, Blennow, Kaj, Fladby, Tormod“…This may have implications for patient selection in future trials. We used CSF markers to determine A/T/N stage using amyloid beta42/40 ratio, p-tau181 and total-tau respectively in predementia Alzheimer’s disease cases (n = 176) [including cases that progressed to dementia (n = 10)] and controls (n = 74) from the Norwegian Dementia Disease Initiation cohort. …”
Publicado 2022
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344275por Mushtaq, Muhammad Umair, Shahzad, Moazzam, Shah, Amna Y., Chaudhary, Sibgha Gull, Zafar, Muhammad U., Anwar, Iqra, Neupane, Karun, Khalid, Ayesha, Ahmed, Nausheen, Bansal, Rajat, Balusu, Ramesh, Singh, Anurag K., Abhyankar, Sunil H., Callander, Natalie S., Hematti, Peiman, McGuirk, Joseph P.“…METHODS: A literature search was performed on PubMed, Cochrane, and Clinical trials.gov through April 20, 2022. We included 21 studies reporting data on the impact of NK cells on outcomes after HSCT. …”
Publicado 2022
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344276por Chen, Yan, Ding, Xiaofang, Zhu, Yueliang, Jia, Zhongwei, Qi, Yong, Chen, Mingyong, Lu, Jili, Kuang, Xiaocong, Zhou, Jia, Su, Yongfeng, Zhao, Yongxin, Lu, William, Zhao, Jinmin, Hua, Qikai“…The findings are required to confirm in randomized controlled trials. The Translational Potential of this Article: TTT can be used as an effective treatment in patients with recalcitrant DFUs. …”
Publicado 2022
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344277por Saber, Hamidreza, Desai, Shashvat M., Haussen, Diogo, Al-bayati, Alhamza, Majidi, Shahram, Mocco, J., Hassan, Ameer E., Rajah, Gary, Waqas, Muhammad, Davies, Jason M., Dornbos, David, Nickele, Christopher, Arthur, Adam S., Mowla, Ashkan, Tenser, Matthew S., Mokin, Maxim, Pressman, Elliot, Aghaebrahim, Amin, Hanel, Ricardo A., Ortega-Gutierrez, Santiago, Jovin, Tudor, Duckwiler, Gary R., Liebeskind, David S., Nogueira, Raul G., Gornbein, Jeffrey, Saver, Jeffrey L., Jadhav, Ashutosh P.“…IMPORTANCE: Randomized clinical trials have shown the efficacy of endovascular therapy (EVT) for acute large vessel occlusion strokes. …”
Publicado 2022
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344278por Fafyman, Maya, Galindo, Rodolfo, Gerges, Amany, Migdal, Alexandra, Peng, Limin, Rashied, Ammar, Umpierrez, Guillermo, Vellanki, Priyanthama, Zabala, Zohyra, Zahid, Syeda“…Little data from randomized clinical trials (RTC) is available to support an intensive vs relaxed BG target. …”
Publicado 2022
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344279por Ashfaq, Akhtar, Strugnell, Stephen, Tabash, Samir, Johnson, Laura, Bishop, Charles W“…BACKGROUND: Extended-release calcifediol (ERC) has been shown in randomized clinical trials to effectively and safely treat secondary hyperparathyroidism (SHPT) in adults with stage 3-4 chronic kidney disease (CKD) and vitamin D insufficiency when administered at 210 or 420 mcg per week (30 or 60 mcg/day), doses which gradually raise serum total 25-hydroxyvitamin D (25D) to mean steady-state levels of 50-56 ng/mL. …”
Publicado 2022
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344280por Chin, Edward, Cotter, Thomas, Harned, Leighton, Vemavarapu, Lakshmi, Harper, Rene“…There are currently ongoing clinical trials of abatacept to treat sarcoidosis and granulomatosis with polyangiitis that may shed light on the efficacy of this drug to treat granulomatous disease. …”
Publicado 2022
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