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344321por Chi, Sang Ah, Yu, Hyeyeon, Choi, Yoon-La, Park, Sehhoon, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Ahn, Myung-Ju, Choi, Dae-Ho, Kim, Kyunga, Jung, Hyun Ae, Park, Keunchil“…However, standard clinical trials may not reflect current multiple lines of treatment and corresponding outcomes in a timely manner. …”
Publicado 2023
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344322por David, Michael C B, Kolanko, Magdalena, Del Giovane, Martina, Lai, Helen, True, Jessica, Beal, Emily, Li, Lucia M, Nilforooshan, Ramin, Barnaghi, Payam, Malhotra, Paresh A, Rostill, Helen, Wingfield, David, Wilson, Danielle, Daniels, Sarah, Sharp, David J, Scott, Gregory“…We show how IoT-based monitoring could improve the management of acute and chronic comorbidities in this clinically vulnerable group. Future randomized trials are required to establish if a system like this has measurable long-term benefits on health and quality of life outcomes.…”
Publicado 2023
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344323por Lailler, Grégory, Grave, Clémence, Gabet, Amélie, Regnault, Nolwenn, Deneux-Tharaux, Catherine, Kretz, Sandrine, Tsatsaris, Vassilis, Plu-Bureau, Geneviève, Blacher, Jacques, Olie, Valérie“…BACKGROUND: Many clinical trials have reported that low-dose aspirin decreases the risk of pre-eclampsia in women with prior pre-eclampsia. …”
Publicado 2023
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344324por Niraula, Dipesh, Sun, Wenbo, Jin, Jionghua, Dinov, Ivo D., Cuneo, Kyle, Jamaluddin, Jamalina, Matuszak, Martha M., Luo, Yi, Lawrence, Theodore S., Jolly, Shruti, Ten Haken, Randall K., El Naqa, Issam“…Datasets of size 117 and 292 were available from two clinical trials on adaptive RT in non-small cell lung cancer (NSCLC) patients and adaptive stereotactic body RT (SBRT) in hepatocellular carcinoma (HCC) patients, respectively. …”
Publicado 2023
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344325por Vercellini, Paolo, Bandini, Veronica, Buggio, Laura, Barbara, Giussy, Berlanda, Nicola, Dridi, Dhouha, Frattaruolo, Maria Pina, Somigliana, Edgardo“…Six studies were randomized controlled trials (RCTs) (double blind, n = 2) and eight adopted a prospective cohort design (non-comparative, n = 6; comparative, n = 2). …”
Publicado 2023
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344326por VandeVrede, Lawren, La Joie, Renaud, Thijssen, Elisabeth H., Asken, Breton M., Vento, Stephanie A., Tsuei, Torie, Baker, Suzanne L., Cobigo, Yann, Fonseca, Corrina, Heuer, Hilary W., Kramer, Joel H., Ljubenkov, Peter A., Rabinovici, Gil D., Rojas, Julio C., Rosen, Howie J., Staffaroni, Adam M., Boeve, Brad F., Dickerson, Brad C., Grossman, Murray, Huey, Edward D., Irwin, David J., Litvan, Irene, Pantelyat, Alexander Y., Tartaglia, Maria Carmela, Dage, Jeffrey L., Boxer, Adam L.“…Plasma P-tau217 may be a useful and inexpensive biomarker to select patients for CBS clinical trials.…”
Publicado 2023
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344327por Raethke, Monika, van Hunsel, Florence, Thurin, Nicolas H., Dureau-Pournin, Caroline, Mentzer, Dirk, Kovačić, Barbara, Mirošević Skvrce, Nikica, De Clercq, Evelien, Sabbe, Martine, Trifirò, Gianluca, Luxi, Nicoletta, Giovanazzi, Alexia, Shakir, Saad, Klungel, Olaf H., Schmikli, Sandor, Sturkenboom, Miriam“…This study demonstrated the feasibility of setting up and conducting cohort event monitoring across multiple European countries to collect safety data on novel vaccines that are rolled out at scale in populations which may not have been included in pivotal trials. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40264-023-01281-9.…”
Publicado 2023
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344328por Kobayashi, Taku, Hoshi, Masato, Yuasa, Akira, Arai, Shoko, Ikeda, Mitsunobu, Matsuda, Hiroyuki, Kim, Seok-Won, Hibi, Toshifumi“…Patient characteristics were sourced from the OCTAVE Induction trials. Mean utilities associated with UC health states and adverse events (AEs) were obtained from published sources. …”
Publicado 2023
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344329por Sava, Manuel-Paul, Hara, Hitomi, Alexandra, Leica, Hügli, Rolf W., Hirschmann, Michael T.“…The quality of included papers, except randomised control trials (RCTs), was evaluated using the Methodological Index for Non-Randomised Studies (MINORS). …”
Publicado 2023
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344330por Goddard, Jack, Castle, Jemma, Southworth, Emily, Fletcher, Anya, Crosier, Stephen, Martin-Guerrero, Idoia, García-Ariza, Miguel, Navajas, Aurora, Masliah-Planchon, Julien, Bourdeaut, Franck, Dufour, Christelle, Ayrault, Olivier, Goschzik, Tobias, Pietsch, Torsten, Sill, Martin, Pfister, Stefan M., Rutkowski, Stefan, Richardson, Stacey, Hill, Rebecca M., Williamson, Daniel, Bailey, Simon, Schwalbe, Edward C., Clifford, Steven C., Hicks, Debbie“…A clinically-annotated discovery cohort (n = 362 MB(Grp4)) was assembled from UK-CCLG institutions and SIOP-UKCCSG-PNET3, HIT-SIOP-PNET4 and PNET HR + 5 clinical trials. Molecular profiling was undertaken, integrating driver mutations, second-generation non-WNT/non-SHH subgroups (1–8) and whole-chromosome aberrations (WCAs). …”
Publicado 2023
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344331por Meng, Xiaojun, Yin, Hanlu, Ma, Wenjuan, Gu, Jing, Lu, Zhen, Fitzpatrick, Thomas, Zou, Huachun“…Future interventional trials are needed to confirm these findings.…”
Publicado 2023
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344332por Dalcin, Arlene Taylor, Yuan, Christina T, Jerome, Gerald J, Goldsholl, Stacy, Minahan, Eva, Gennusa, Joseph, Fink, Tyler, Gudzune, Kimberly A, Daumit, Gail Lois, Dickerson, Faith, Thompson, David A, Wang, Nae-Yuh, Martino, Steve“…BACKGROUND: Motivational interviewing (MI) is an evidence-based, patient-centered communication method shown to be effective in helping persons with serious mental illness (SMI) to improve health behaviors. In clinical trials where study staff conducted lifestyle interventions incorporating an MI approach, cardiovascular disease (CVD) risk profiles of participants with SMI showed improvement. …”
Publicado 2023
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344333por Wang, Xiqiang, Ma, Yanpeng, Liu, Zhongwei, Fan, Xiude, Guan, Gongchang, Pan, Shuo, Wang, Junkui, Zhang, Yong“…CONCLUSION: TTVr has shown to have favorable outcomes compared to STVr or STVR, but more research and clinical trials are required to help formulate evidence-based guidelines for the role of catheter-based management in tricuspid valve disease. …”
Publicado 2023
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344334“…METHODS: PubMed, EMBASE, ScienceDirect, Cochrane Library, China Journal full-text Database (CNKI), VIP full-text Database, Wanfang Database and Chinese Biomedical Literature data (CBM), search relevant Chinese and foreign periodicals, conference papers, degree papers, etc. were searched Database and China Biomedical Literature Database (CBM) to search case-control trials of Aidi injection when treating NSCLC patients. …”
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344335por Robinson, Dale L., Bucknill, Andrew, Ferragina, Alessandro, Campbell, Christopher, Lee, Peter Vee Sin“…There have been a number of recent trials using metallic 3D-printed pelvic fracture plates to simplify and improve various elements of these fracture fixation surgeries; however, the amount of time and accuracy involved in the design and implantation of customised plates have not been well characterised. …”
Publicado 2023
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344336por Straube, F, Dorwarth, U, Pongratz, J, Riess, L, Kuniss, M, Tebbenjohanns, J, Noelker, G, Tilz, R, Chun, J, Stellbrink, C, Metzner, A, Brachmann, J, Kuck, K H, Senges, J, Hoffmann, E“…METHODS: This is a sub-analysis of the prospective multi-center FREEZE Cohort Study (ClinicalTrials.gov, NCT01360008). QoL changes were assessed by EQ-5D-3L self-report questionnaire and by EHRA symptom score at baseline and follow-up. …”
Publicado 2023
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344337por Schechter, Meir, Melzer Cohen, Cheli, Fishkin, Alisa, Rozenberg, Aliza, Yanuv, Ilan, Sehtman-Shachar, Dvora R., Chodick, Gabriel, Clark, Alice, Abrahamsen, Trine J., Lawson, Jack, Karasik, Avraham, Mosenzon, Ofri“…BACKGROUND: In clinical trials enrolling patients with type 2 diabetes (T2D) at high cardiovascular risk, many glucagon-like peptide-1 receptor agonists (GLP-1 RAs) improved albuminuria status and possibly mitigated kidney function loss. …”
Publicado 2023
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344338por Hortobágyi, Tibor, Vetrovsky, Tomas, Brach, Jennifer S., van Haren, Martijn, Volesky, Krystof, Radaelli, Regis, Lopez, Pedro, Granacher, Urs“…Randomized controlled trials were included that examined the effects of exercise training on muscle quality (MQ) in older individuals with and without neurological conditions. …”
Publicado 2023
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344339por Levin, Daniel S., Ferretti, Claudio, Ristow, Nicholas, Tecchio, Monica, Friedman, Peter S., Litzenberg, Dale W., Bashkirov, Vladimir, Schulte, Reinhard“…BACKGROUND: FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in conventional RT. For clinical trials to be conducted safely, precise and fast beam monitoring that can generate an out-of-tolerance beam interrupt is required. …”
Publicado 2023
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344340por Huang, Yi-lin, Xu, Xiao-zhuo, Liu, Jing, Wang, Pin-yao, Wang, Xue-li, Feng, Hong-lin, Liu, Cheng-jiang, Han, Xu“…This meta-analysis included randomized controlled trials (RCTs) and a small number of cohort studies. …”
Publicado 2023
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