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  1. 344361
    “…RESULTS: In step 1, we completed a needs assessment consisting of assembling a planning group to codevelop the intervention, conducting telephone surveys of people after stroke (n=125) to identify service needs, and performing a systematic review of randomized controlled trials to examine evidence of the effectiveness of digital self-management interventions to improve patient outcomes. …”
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    Using Intervention Mapping and Behavior Change Techniques to Develop a Digital Intervention for Self-Management in Stroke: Development Study
  2. 344362
    “…BACKGROUND: Data from clinical trials of lumacaftor-ivacaftor (LUM-IVA) demonstrate improvements in lung clearance index (LCI) but not in FEV(1) in children with Cystic Fibrosis (CF) aged 6–11 years and homozygous for the Phe508del mutation. …”
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    The clinical impact of Lumacaftor-Ivacaftor on structural lung disease and lung function in children aged 6–11 with cystic fibrosis in a real-world setting
  3. 344363
    “…METHODS: Multiple electronic databases were searched to identify the randomized controlled trials (RCTs) examining the use of TCM in the treatment of ONFH. …”
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    Efficacy and safety of traditional Chinese medicine in the treatment of osteonecrosis of the femoral head
  4. 344364
    “…The risk of bias was assessed using the Cochrane Risk of Bias Tool for randomised controlled trials and the Risk of Bias in Systematic Reviews tool for systematic reviews. …”
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    Effect of monitoring adherence to regular inhaled corticosteroid (ICS) alone or in combination with a long-acting β2-agonist (LABA) using electronic methods on asthma outcomes: a narrative systematic review
  5. 344365
    “…BACKGROUND: Dalfampridine (Ampyra) is indicated to improve walking in patients with multiple sclerosis (MS) and was found to be effective in 35%-43% of individuals with MS in clinical trials. Dalfampridine may increase seizure risk, particularly in patients with renal impairment. …”
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    Dalfampridine Prior Authorization Program: A Cohort Study
  6. 344366
    “…For the 12-month period following the index date (fixed length of follow-up), the study compared per-patient per-year (PPPY) costs for (1) patients who switched versus those who did not switch and (2) patients with single versus multiple trials of SSRI for the subgroup of patients who switched from an SSRI to venlafaxine. …”
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    Pharmacy and Medical Costs Associated With Switching Between Venlafaxine and SSRI Antidepressant Therapy for the Treatment of Major Depressive Disorder
  7. 344367
    por Golden, Sherita Hill, Sapir, Tamar
    Publicado 2012
    “…SUMMARY: The AHRQ systematic review of randomized clinical trials reveals that both insulin delivery modalities (CSII and MDI) demonstrate similar effectiveness on glycemic control and severe hypoglycemia in children and adolescents with T1DM and in adults with T2DM. …”
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    Methods for Insulin Delivery and Glucose Monitoring in Diabetes: Summary of a Comparative Effectiveness Review
  8. 344368
    “…Treatment efficacies were modeled from results of randomized clinical trials, including the time and rate of A1c drift. …”
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    The Evaluation of Clinical and Cost Outcomes Associated with Earlier Initiation of Insulin in Patients with Type 2 Diabetes Mellitus
  9. 344369
    “…RESULTS: Seventeen articles (20 trials, 1652 patients) were included. IPACK supplementation significantly reduced rest pain scores after total knee arthroplasty at postoperative hours 8–12(95%CI − 0.85 [− 1.36, − 0.34], I(2) = 94%, p = 0.001), postoperative day 1 (95% CI − 0.49 [− 0.85, − 0.14], I(2) = 87%, p = 0.006), and postoperative day 2 (95% CI − 0.28 [− 0.51, -0.05], I2 = 72%, p = 0.02); there was no significant difference at postoperative day 3 or discharge (95% CI − 0.14 [− 0.33, 0.05], I(2) = 0%, p = 0.14). …”
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    Clinical effects of interspace between the popliteal artery and capsule of the posterior knee block with multimodal analgesia for total knee arthroplasty: a systematic review and meta-analysis
  10. 344370
    “…The purpose of this systematic review and meta-analysis is to evaluate the safety and efficacy of TXA compared to placebo treatment during or after AS surgery, by gathering data from randomized both controlled trials (RCTs) and non-RCTs. METHODS: English and Chinese electronic databases including PubMed, Web of Science, Embase, Cochrane, CNKI, and Wan Fang database were searched to identify the relevant literature up until August 2022. …”
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    Tranexamic acid can reduce blood loss in adolescent scoliosis surgery: a systematic review and meta-analysis
  11. 344371
    “…These results might help in designing pathogenesis studies and in selecting high-risk patients for inclusion in therapeutic and management clinical trials. FUNDING: The study received funding from the Horizon 2020 ORCHESTRA project, grant 101016167; from the 10.13039/501100001826Netherlands Organisation for Health Research and Development (ZonMw), grant 10430012010023; from 10.13039/501100001677Inserm, REACTing (REsearch & ACtion emergING infectious diseases) consortium and the French Ministry of Health, grant PHRC 20-0424.…”
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    Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohort
  12. 344372
    “…METHODS: Cochrane central, MEDLINE (Subset PubMed), EMBASE, Web of Science, http://www.ClinicalTrials.gov and Google scholar were searched for relevant publications involving BP-DES in patients with DM versus non-DM and their associated adverse cardiovascular outcomes. …”
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    Long-term cardiovascular outcomes of biodegradable polymer drug eluting stents in patients with diabetes versus non-diabetes mellitus: a meta-analysis
  13. 344373
    “…CONCLUSION: At a group level the retrospectively collected pre-COVID-19 EQ-5D-5L is adequate and makes it possible to directly evaluate the impact of COVID-19 on HRQoL. (ClinicalTrials.gov NCT05160636) SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12955-023-02187-x.…”
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    Assessment of retrospective collection of EQ-5D-5L in a US COVID-19 population
  14. 344374
    “…These findings help to guide participant recruitment for clinical trials targeting prodromal genetic FTD.…”
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    Clinical Value of Longitudinal Serum Neurofilament Light Chain in Prodromal Genetic Frontotemporal Dementia
  15. 344375
    “…This study has been registered in ClinicalTrials.gov with the number NCT04994197 posted on August 2021. …”
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    A urinary assay for mutation and methylation biomarkers in the diagnosis and recurrence prediction of non-muscle invasive bladder cancer patients
  16. 344376
    “…METHOD: The pharmacokinetic data of dorzagliatin in this study came from six clinical trials. Based on the combined data, a population pharmacokinetic model of dorzagliatin was established using NONMEM software (ICON, MD, USA, version 7.4.3). …”
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    Population Pharmacokinetic Analysis of Dorzagliatin in Healthy Subjects and Patients with Type 2 Diabetes Mellitus
  17. 344377
    por Li, Qiang, Liu, Pan, Wang, Zongbao, Li, Xin
    Publicado 2023
    “…METHODS: PubMed, Cochrane Library, Web of Science, Embase, CNKI, Wanfang Date, VIP, and CBM were applied to search for clinical randomized controlled trials (RCTs) on vibration therapy for people with CLBP. …”
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    Vibration therapy to improve pain and function in patients with chronic low back pain: a systematic review and meta-analysis
  18. 344378
    “…DESIGN: A computerized literature (using a specific search strategy) search was performed across the databases MEDLINE, EMBASE, COCHRANE CENTRAL, SCOPUS and WEB OF SCIENCE up to June 2023 in order to identify randomized controlled trials (RCTs) evaluating the effect of endometrial scratching prior to an embryo transfer cycle on the probability of pregnancy, expressed either as live birth, ongoing pregnancy or clinical pregnancy (in order of significance) compared to placebo/sham or no intervention. …”
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    The role of endometrial scratching prior to in vitro fertilization: an updated systematic review and meta-analysis
  19. 344379
    “…Patients have reported injection site reactions, frustration, and breakthrough acromegaly symptoms between doses. Two trials were conducted which showed that oral octreotide is an effective alternative for patients after achieving biochemical control with the injectable formulation. …”
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    THU028 Novel Approach To Management Of Acromegaly With De Novo Oral Octreotide Or Combination Therapy With Cabergoline: A Case Series
  20. 344380
    “…While previous activin targeting agents have shown therapeutic promise in clinical trials, full pathway inhibition remains unachieved. …”
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    FRI112 HS135, A Novel Activin And GDF Trap With Dual Cardiopulmonary And Metabolic Mode Of Action, Is Efficacious In An Obesogenic Model Of Heart Failure
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