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344521por Seo, Dongjin, Park, Yu Rang, Lee, Yura, Kim, Ji Young, Park, Joong-Yeol, Lee, Jae-Ho“…BACKGROUND: The effectiveness of personal health records (PHRs) in diabetes management has already been verified in several clinical trials; however, evidence of their effectiveness in real-world scenarios is also necessary. …”
Publicado 2020
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344522por Nochaiwong, Surapon, Ruengorn, Chidchanok, Awiphan, Ratanaporn, Ruanta, Yongyuth, Boonchieng, Waraporn, Nanta, Sirisak, Kowatcharakul, Woravut, Pumpaisalchai, Wanida, Kanjanarat, Penkarn, Mongkhon, Pajaree, Thavorn, Kednapa, Hutton, Brian, Wongpakaran, Nahathai, Wongpakaran, Tinakon“…The findings will be disseminated through public, scientific, and professional meetings, and publications in peer-reviewed journals. THAI CLINICAL TRIALS REGISTRY (TCTR) REGISTRATION NUMBER: TCTR20200425001.…”
Publicado 2020
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344523por Brendel, Matthias, Barthel, Henryk, van Eimeren, Thilo, Marek, Ken, Beyer, Leonie, Song, Mengmeng, Palleis, Carla, Gehmeyr, Mona, Fietzek, Urban, Respondek, Gesine, Sauerbeck, Julia, Nitschmann, Alexander, Zach, Christian, Hammes, Jochen, Barbe, Michael T., Onur, Oezguer, Jessen, Frank, Saur, Dorothee, Schroeter, Matthias L., Rumpf, Jost-Julian, Rullmann, Michael, Schildan, Andreas, Patt, Marianne, Neumaier, Bernd, Barret, Olivier, Madonia, Jennifer, Russell, David S., Stephens, Andrew, Roeber, Sigrun, Herms, Jochen, Bötzel, Kai, Classen, Joseph, Bartenstein, Peter, Villemagne, Victor, Levin, Johannes, Höglinger, Günter U., Drzezga, Alexander, Seibyl, John, Sabri, Osama“…Future interventional trials against tau in PSP would strongly benefit from biomarkers that support diagnosis. …”
Publicado 2020
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344524por VINCENT, Patrice“…Cette large base de données a été entièrement retraitée en 2019, de manière à fournir une analyse séparée par stade KL, et fut complétée par l’évaluation des taux de patients répondeurs (%) au traitement, selon l'Outcome Measures in Rheumatoid Arthritis Clinical Trials & Osteoarthritis Research Society International (OMERACT-OARSI). …”
Publicado 2020
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344525por Sharkey, Thomas, Whatnall, Megan C., Hutchesson, Melinda J., Haslam, Rebecca L., Bezzina, Aaron, Collins, Clare E., Ashton, Lee M.“…METHODS: Six electronic databases were searched for randomised controlled trials (RCTs) published up to December 2019 that evaluated nutrition, physical activity and/or overweight/obesity interventions in young adults (17–35 years). …”
Publicado 2020
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344526por Borodovsky, Alexandra, Barbon, Christine M, Wang, Yanjun, Ye, Minwei, Prickett, Laura, Chandra, Dinesh, Shaw, Joseph, Deng, Nanhua, Sachsenmeier, Kris, Clarke, James D, Linghu, Bolan, Brown, Giles A, Brown, James, Congreve, Miles, Cheng, Robert KY, Dore, Andrew S, Hurrell, Edward, Shao, Wenlin, Woessner, Richard, Reimer, Corinne, Drew, Lisa, Fawell, Stephen, Schuller, Alwin G, Mele, Deanna A“…This unique mechanism of action in CD103(+) DCs may contribute to clinical responses as AZD4635 is being evaluated in clinical trials with IMFINZI (durvalumab, αPD-L1) in patients with solid malignancies. …”
Publicado 2020
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344527por Iversen, Kasper, Bundgaard, Henning, Hasselbalch, Rasmus B, Kristensen, Jonas H, Nielsen, Pernille B, Pries-Heje, Mia, Knudsen, Andreas D, Christensen, Casper E, Fogh, Kamille, Norsk, Jakob B, Andersen, Ove, Fischer, Thea K, Jensen, Claus Antonio Juul, Larsen, Margit, Torp-Pedersen, Christian, Rungby, Jørgen, Ditlev, Sisse B, Hageman, Ida, Møgelvang, Rasmus, Hother, Christoffer E, Gybel-Brask, Mikkel, Sørensen, Erik, Harritshøj, Lene, Folke, Fredrik, Sten, Curt, Benfield, Thomas, Nielsen, Susanne Dam, Ullum, Henrik“…The study is registered at ClinicalTrials.gov, NCT04346186. INTERPRETATION: The prevalence of health-care workers with antibodies against SARS-CoV-2 was low but higher than in blood donors. …”
Publicado 2020
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344528por Artese, Anna, Svicher, Valentina, Costa, Giosuè, Salpini, Romina, Di Maio, Velia Chiara, Alkhatib, Mohammad, Ambrosio, Francesca Alessandra, Santoro, Maria Mercedes, Assaraf, Yehuda G., Alcaro, Stefano, Ceccherini-Silberstein, Francesca“…The attention has been focused on antiviral drugs mainly targeting viral protease, RNA polymerase and spike glycoprotein, that have been tested in vitro and/or in clinical trials as well as on promising compounds proven to be active against coronaviruses by an in silico drug repurposing approach. …”
Publicado 2020
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344529“…We tested the effects of the activity monitor and mobility status on the absolute difference in step count error (%) and computed the standard error of measurement (SEM) between repeat trials. To assess criterion validity, participants completed two 400-meter overground walks at a usual pace while wearing all monitors. …”
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344530por Tepper, Stewart J., Vasudeva, Raghavendra, Krege, John H., Rathmann, Suchitrita S., Doty, Erin, Vargas, Bert B., Magis, Delphine, Komori, Mika“…METHODS: Pooled analyses were completed from 2 Phase 3 double‐blind clinical trials, SPARTAN and SAMURAI. Data from baseline to 2 hours after taking lasmiditan (50, 100, or 200 mg) or placebo were analyzed to assess efficacy based on patient characteristics, migraine disease characteristics, and migraine attack characteristics. …”
Publicado 2020
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344531por Verberk, Inge M. W., Thijssen, Elisabeth, Koelewijn, Jannet, Mauroo, Kimberley, Vanbrabant, Jeroen, de Wilde, Arno, Zwan, Marissa D., Verfaillie, Sander C. J., Ossenkoppele, Rik, Barkhof, Frederik, van Berckel, Bart N. M., Scheltens, Philip, van der Flier, Wiesje M., Stoops, Erik, Vanderstichele, Hugo M., Teunissen, Charlotte E.“…BACKGROUND: Blood-based biomarkers for Alzheimer’s disease (AD) might facilitate identification of participants for clinical trials targeting amyloid beta (Abeta) accumulation, and aid in AD diagnostics. …”
Publicado 2020
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344532por Borovac, Josip A., Glavas, Duska, Susilovic Grabovac, Zora, Supe Domic, Daniela, Stanisic, Lada, D'Amario, Domenico, Kwok, Chun S., Bozic, Josko“…CONCLUSIONS: Elevated sST2 and CST levels, reflecting two distinct pathophysiological pathways in heart failure, might indicate impending clinical deterioration among AWHF patients during hospitalization and facilitate prognosis beyond traditional biomarkers regarding the risk of in‐hospital death (CATSTAT‐HF ClinicalTrials.gov Number NCT03389386).…”
Publicado 2020
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344533por Abel, Shawna, Vavasour, Irene, Lee, Lisa Eunyoung, Johnson, Poljanka, Ristow, Stephen, Ackermans, Nathalie, Chan, Jillian, Cross, Helen, Laule, Cornelia, Dvorak, Adam, Schabas, Alice, Hernández-Torres, Enedino, Tam, Roger, Kuan, Annie J., Morrow, Sarah A., Wilken, Jeffrey, Rauscher, Alexander, Bhan, Virender, Sayao, Ana-Luiza, Devonshire, Virginia, Li, David K. B., Carruthers, Robert, Traboulsee, Anthony, Kolind, Shannon H.“…MWI offers an in vivo biomarker feasible for use in clinical trials investigating cognition, providing a means for monitoring changes in myelination and its association with symptom worsening or improvement.…”
Publicado 2020
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344534“…All the players were instructed to complete the test setup (4 conditions, 5 trials) as fast as possible. Condition 1 includes no constraint, condition 2 includes a task constraint (football dummies), condition 3 includes an environmental constraint (stroboscopic glasses) (SENAPTEC, Beaverton, Oregon) and condition 4 includes both task and environmental constraints. 3-D kinematics of the hip, knee, ankle joints were captured using Xsens wearable full-body sensor suits (Xsens, MVN Link version, Enschede, The Netherlands). …”
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344535por Mytton, Oliver T., Boyland, Emma, Adams, Jean, Collins, Brendan, O’Connell, Martin, Russell, Simon J., Smith, Kate, Stroud, Rebekah, Viner, Russell M., Cobiac, Linda J.“…This is a modelling study and subject to uncertainty; we cannot fully and accurately account for all of the factors that would affect the impact of this policy if implemented. Whilst randomised trials show that children exposed to less-healthy food advertising consume more calories, there is uncertainty about the nature of the dose–response relationship between HFSS advertising and calorie intake. …”
Publicado 2020
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344536“…For chemoprophylaxis, trials were performed with dapsone/acedapsone, rifampicin, and ROM, a combination of rifampicin, ofloxacin, and minocycline. …”
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344537por Williams, Erik A., Santagata, Sandro, Wakimoto, Hiroaki, Shankar, Ganesh M., Barker, Fred G., Sharaf, Radwa, Reddy, Abhinav, Spear, Phoebe, Alexander, Brian M., Ross, Jeffrey S., Brastianos, Priscilla K., Cahill, Daniel P., Ramkissoon, Shakti H., Juratli, Tareq A.“…Overall, these data increase our understanding of the pathobiology of high-grade/progressive meningiomas and can guide the design of clinical trials. IRB APPROVAL STATUS: Reviewed and approved by Western IRB; Protocol No. 20152817. …”
Publicado 2020
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344538por Khan, Mohammed Yunus, Pandit, Sucheta, Ray, Saumitra, Mohan, Jagdish Chander, Srinivas, B. C., Ramakrishnan, Santosh, Mane, Amey, Mehta, Suyog, Shah, Snehal“…BACKGROUND: The effectiveness of amlodipine has been reported in clinical trials in India. However, real-world data on the effectiveness of amlodipine in India is limited. …”
Publicado 2020
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344539Publicado 2023“…The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025. FINDINGS: Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. …”
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344540por Roumier, Mathilde, Paule, Romain, Vallée, Alexandre, Rohmer, Julien, Ballester, Marie, Brun, Anne-Laure, Cerf, Charles, Chabi, Marie-Laure, Chinet, Thierry, Colombier, Marie-Alice, Farfour, Eric, Fourn, Erwan, Géri, Guillaume, Khau, David, Marroun, Ibrahim, Ponsoye, Matthieu, Roux, Antoine, Salvator, Hélène, Schoindre, Yoland, Si Larbi, Anne-Gaëlle, Tchérakian, Colas, Vasse, Marc, Verrat, Anne, Zuber, Benjamin, Couderc, Louis-Jean, Kahn, Jean-Emmanuel, Groh, Matthieu, Ackermann, Félix“…CONCLUSION: These data could be helpful for the design of future trials aiming to counter COVID-19-induced inflammation, especially before patients require admission to the intensive care unit. …”
Publicado 2020
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