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344581“…METHODS: A structured search of CINAHL, Cochrane Library/trials, EMBASE, PubMed, SCOPUS, Web of Science, and HRH Global Resource Centre databases was undertaken, guided by the PRISMA framework. …”
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344582por Saadoun, David, Vieira, Matheus, Vautier, Mathieu, Baraliakos, Xenofon, Andreica, Ioana, da Silva, José A P, Sousa, Marlene, Luis, Mariana, Khmelinskii, Nikita, Gracía, José María Alvaro, Castrejon, Isabel, Gonzalez, Juan Carlos Nieto, Scirè, Carlo Alberto, Silvagni, Ettore, Bortoluzzi, Alessandra, Penn, Henry, Hamdulay, Shahir, Machado, Pedro M, Fautrel, Bruno, Cacoub, Patrice, Resche-Rigon, Matthieu, Gossec, Laure“…This study is registered with ClinicalTrials.gov, NCT04397237. FINDINGS: Between June 7 and Dec 8, 2020, 3136 patients with an immune-mediated inflammatory disease answered the questionnaire. 3028 patients (median age 58 years [IQR 46–67]; 2239 [73·9%] women and 789 [26·1%] men) with symptomatic COVID-19, serological data, or both were included in analyses. …”
Publicado 2021
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344583“…Firstly, because clinical trials with MC4R-agonists have raised expectations regarding the treatment of patients with mutations of the LEPR gene. …”
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344584“…There are several published trials using TKIs for redifferentiation based on the mutation present. …”
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344585“…Oral contraceptives had been previously trialed and failed to induce withdrawal bleeding. …”
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344586por Petersenn, Stephan, Houchard, Aude, Schneider, Maria del Pilar, Ribeiro-Oliveira, Antonio, Neggers, Sebastian Jcmm“…Methods: This post-hoc analysis reports data from the PRIMARYS(5) (NCT00690898) and LEAD(6) (NCT00701363) open-label trials in which adult patients with acromegaly received LAN. …”
Publicado 2021
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344587por Cano Porras, Desiderio, Jacobs, Jesse V., Inzelberg, Rivka, Bahat, Yotam, Zeilig, Gabriel, Plotnik, Meir“…Visual perturbations elicited muscle activation in 67.7% of trials. CONCLUSION: Our results demonstrate that vertical (vs. horizontal) perturbations generate unique balance-correcting muscle activations, which were consistent with counteracting vertical body extension induced by downward perturbations and vertical body flexion induced by upward perturbations. …”
Publicado 2021
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344588Publicado 2021“…This study is registered on ClinicalTrials.gov, NCT04367207. FINDINGS: From May to December, 2020, 6779 patients were referred to critical care. …”
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344589por Belay, Mulugeta, Tulu, Begna, Younis, Sidra, Jolliffe, David A, Tayachew, Dawit, Manwandu, Hana, Abozen, Tenagnework, Tirfie, Emawayish A, Tegegn, Metasebia, Zewude, Aboma, Forrest, Sally, Mayito, Jonathan, Huggett, Jim F, Jones, Gerwyn M, O'Sullivan, Denise M, Martineau, Henny M, Noursadeghi, Mahdad, Chandran, Aneesh, Harris, Kathryn A, Nikolayevskyy, Vlad, Demaret, Julie, Berg, Stefan, Vordermeier, Martin, Balcha, Taye T, Aseffa, Abraham, Ameni, Gobena, Abebe, Markos, Reece, Stephen T, Martineau, Adrian R“…Detection of M tuberculosis complex DNA in PBMCs has potential applications in the diagnosis of latent tuberculosis infection, in monitoring response to preventive therapy, and as an outcome measure in clinical trials of interventions to prevent or treat latent tuberculosis infection. …”
Publicado 2021
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344590por Liu, Lu, Tian, Tian, Li, Xiang, Wang, Yanan, Xu, Tao, Ni, Xixiu, Li, Xiao, He, Zhenxi, Gao, Shan, Sun, Mingsheng, Liang, Fanrong, Zhao, Ling“…Methods: Using search terms about acupuncture, neuroimaging and migraine, we searched PubMed, Embase, Cochrane Central Register of Controlled Trials, and China National Knowledge Infrastructure from January 2009 to June 2020 for neuroimaging studies that examined the effect of acupuncture in migraine. …”
Publicado 2021
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344591“…Nous avons sélectionné les études admissibles à partir des bases de données MEDLINE, Embase, ClinicalTrials.gov, medRxiv et Cochrane au 29 janvier 2021, en utilisant les Medical Subject Headings (vedettes matière en médecine) et les expressions clés « severe acute respiratory syndrome coronavirus 2 OR SARS-CoV-2 OR coronavirus disease 2019 OR COVID-19 » (coronavirus du syndrome respiratoire aigu sévère 2 ou SRAS-CoV-2 ou maladie à coronavirus 2019 ou COVID-19) AND « pregnancy » (grossesse). …”
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344592“…Future randomized controlled trials with diverse samples are warranted to confirm our findings.…”
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344593por O'Connell, James, Abbas, Manzar, Beecham, Sarah, Buckley, Jim, Chochlov, Muslim, Fitzgerald, Brian, Glynn, Liam, Johnson, Kevin, Laffey, John, McNicholas, Bairbre, Nuseibeh, Bashar, O'Callaghan, Michael, O'Keeffe, Ian, Razzaq, Abdul, Rekanar, Kaavya, Richardson, Ita, Simpkin, Andrew, Storni, Cristiano, Tsvyatkova, Damyanka, Walsh, Jane, Welsh, Thomas, O'Keeffe, Derek“…Articles that were acceptable for inclusion in this evidence synthesis were peer-reviewed publications, cohort studies, randomized trials, modeling studies, technical reports, white papers, and media reports related to digital contact tracing. …”
Publicado 2021
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344594por Naarding, Karin J., Keene, Kevin R., Sardjoe Mishre, Aashley S.D., Veeger, Thom T.J., van de Velde, Nienke M., Prins, Arina J., Burakiewicz, Jedrzej, Verschuuren, Jan J.G.M., van der Holst, Menno, Niks, Erik H., Kan, Hermien E.“…BACKGROUND: Clinical trials in Duchenne muscular dystrophy (DMD) focus primarily on ambulant patients. …”
Publicado 2021
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344595por Ciapponi, Agustín, Bardach, Ariel, Mazzoni, Agustina, Alconada, Tomás, Anderson, Steven, Argento, Fernando J., Ballivian, Jamile, Bok, Karin, Comandé, Daniel, Erbelding, Emily, Goucher, Erin, Kampmann, Beate, Karron, Ruth, Munoz, Flor M., Palermo, María Carolina, Parker, Edward P. K., Cairoli, Federico Rodriguez, Santa, María Victoria, Stergachis, Andy, Voss, Gerald, Xiong, Xu, Zamora, Natalia, Zaraa, Sabra, Berrueta, Mabel, Buekens, Pierre M.“…The most frequent study design was cohort studies (n=21), followed by surveillance studies, randomized controlled trials, and registry analyses. Most studies (76%) allowed comparisons between vaccinated and unvaccinated pregnant women (n=25) or animals (n=3) and reported exposures during the three trimesters of pregnancy. …”
Publicado 2021
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344596por Prakash, Ajay, Singh, Harvinder, Sarma, Phulen, Bhattacharyya, Anusuya, Dhibar, Deba Prasad, Balaini, Neeraj, Shree, Ritu, Goyal, Manoj, Modi, Manish, Medhi, Bikash“…However, none of the publication had primary or secondary objectives of searching neurological manifestations in the COVID-19 patients and the pathogenic mechanism which will subsequently strengthen the importance to start more prospective clinical trials. The prevalence of neurological signs and symptoms were taken as primary objective. …”
Publicado 2021
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344597por Li, Xingzhe, Kitpanit, Sarin, Lee, Anna, Mah, Dennis, Sine, Kevin, Sherman, Eric J., Dunn, Lara A., Michel, Loren S., Fetten, James, Zakeri, Kaveh, Yu, Yao, Chen, Linda, Kang, Jung Julie, Gelblum, Daphna Y., McBride, Sean M., Tsai, Chiaojung J., Riaz, Nadeem, Lee, Nancy Y.“…CONCLUSIONS AND RELEVANCE: In this study, curative-intent radiotherapy with IMPT for nonmetastatic NPC was associated with significantly reduced acute toxicity burden in comparison with IMRT, with rare late complications and excellent oncologic outcomes, including 100% locoregional control at 2 years. Prospective trials are warranted to direct the optimal patient selection for IMPT as the primary radiotherapy modality for nonmetastatic NPC.…”
Publicado 2021
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344598por Javadivala, Zeinab, Allahverdipour, Hamid, Asghari Jafarabadi, Mohammad, Azimi, Somaye, Gilani, Neda, Chattu, Vijay Kumar“…METHOD: In this systematic review and meta-analysis, the randomized clinical trials (RCTs) published between 2000 and July 26, 2019, were retrieved from several online electronic databases such as Medline, Embase, ProQuest, and Cochrane Library. …”
Publicado 2021
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344599por Bauer, Witold, Adamska-Patruno, Edyta, Krasowska, Urszula, Moroz, Monika, Fiedorczuk, Joanna, Czajkowski, Przemyslaw, Bielska, Dorota, Gorska, Maria, Kretowski, Adam“…This study was registered at ClinicalTrials.gov as NCT03792685. The TT-genotype carriers stratified to the upper protein intake quantiles presented higher HbA1c levels than the CT- and CC-genotype participants in the same quantiles (p = 0.038 and p = 0.022, respectively). …”
Publicado 2021
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344600“…Randomized controlled trials (RCTs) on the Effects of Aspirin with Combined Compound Danshen Dropping Pills on Hemorheology and Blood Lipids in Middle-aged and Elderly Patients with CHD were found following a search of 4 mainstream medical databases. …”
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