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  1. 344921
    “…This study is registered at the Brazilian Registry of Clinical Trials, U1111-1217-6021. FINDINGS: From Feb 6, 2018, to June 30, 2021, 9979 participants were screened and 9509 were enrolled (Brazil n=3928, Mexico n=3288, and Peru n=2293). 543 (5·7%) participants were transgender women, 8966 (94·3%) were cisgender men, and 2481 (26·1%) were aged 18–24 years. …”
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    Same-day initiation of oral pre-exposure prophylaxis among gay, bisexual, and other cisgender men who have sex with men and transgender women in Brazil, Mexico, and Peru (ImPrEP): a prospective, single-arm, open-label, multicentre implementation study
  2. 344922
    “…To this end, we examined and performed a meta-analysis (MA) of the evidence available from randomised controlled trials (RCTs) of Danshen preparations conducted in patients with VCI. …”
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    Clinical efficacy of Danshen preparation in the treatment of vascular cognitive impairment: A systematic review and meta-analysis
  3. 344923
    “…DESIGN: Systematic review with meta-analysis of (randomized) controlled trials. DATA SOURCES: A systematic literature search was conducted in the databases PubMed, Web of Science, Cochrane Library, and SPORTDiscus up to May 2022. …”
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    Chronic Effects of Static Stretching Exercises on Muscle Strength and Power in Healthy Individuals Across the Lifespan: A Systematic Review with Multi-level Meta-analysis
  4. 344924
    “…Only randomized controlled trials evaluating ginseng in combination with chemotherapy versus chemotherapy alone in NSCLC patients were included. …”
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    The Efficacy and Hemorheological Indexes of Ginseng and Its Active Components for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis
  5. 344925
    “…Systemic exposure (C(trough) and AUC) of roflumilast and roflumilast N-oxide in two phase III trials (DERMIS-1, n = 245; DERMIS-2, n = 250) of roflumilast cream 0.3% for 8 weeks was assessed at Weeks 4 and 8. …”
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    Pharmacokinetics of Roflumilast Cream in Chronic Plaque Psoriasis: Data from Phase I to Phase III Studies
  6. 344926
    “…Limited evidence is available to suggest that consumption of low-calorie ED and ES during training and/or weight loss trials may provide ergogenic benefit and/or promote additional weight control, potentially through enhanced training capacity. …”
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    International society of sports nutrition position stand: energy drinks and energy shots
  7. 344927
    “…SEARCH METHODS: We searched the following databases without any language restriction up to 30 January 2014: Cochrane Infectious Diseases Group Specialized Register; MEDLINE; EMBASE; ISI Web of Knowledge; MEDION; LILACS; BIOSIS; SCOPUS; the metaRegister of Controlled Trials; the search portal of the World Health Organization International Clinical Trials Registry Platform; and ProQuest Dissertations & Theses A&I. …”
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    The diagnostic accuracy of the GenoType® Mtbdrsl assay for the detection of resistance to second-line anti-tuberculosis drugs
  8. 344928
    “…SELECTION CRITERIA: Any study that included experimental evaluations (randomized controlled trials) of interventions developed for use in the public sector (e.g., public administration, education, health, etc.) to curb administrative corruption has been included in this review without any geographical or temporal limitations. …”
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    Public sector reforms and their impact on the level of corruption: A systematic review
  9. 344929
    “…Even though each of them was not directly compared in clinical trials at the time, NHSE clearly specified the order in which treatment option should be considered. …”
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    P37 A retrospective audit of molnupiravir prescribing in the virtual hospital via the CMDU pathway
  10. 344930
    “…Further assisted reproductive attempts need to be carefully examined in humans during clinical trials. WIDER IMPLICATIONS OF THE FINDINGS: Our work provides functional evidence that mutations in the ADAD2 gene are deleterious and cause consistent spermiogenic defects in both humans and mice. …”
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    Biallelic mutations in RNA-binding protein ADAD2 cause spermiogenic failure and non-obstructive azoospermia in humans
  11. 344931
    “…The MEDLINE (Pubmed), EMBASE, and Cochrane Central Register of Trials were queried. Screening and full-text review of studies was conducted by two independent evaluators using predetermined inclusion and exclusion criteria. …”
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    Safety and Effectiveness of Limited Incision Facelifts: A Systematic Review and Meta-analysis
  12. 344932
    “…SELECTION CRITERIA: We included randomised controlled trials (RCTs) and quasi‐experimental designs (QEDs) with parallel cohorts and statistical controls for between‐group differences at baseline. …”
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    Functional Family Therapy for families of youth (age 11–18) with behaviour problems: A systematic review and meta‐analysis
  13. 344933
    “…Last, the methodological quality of all trials was mostly satisfactory. In conclusion, in the treatment of traumatic central nervous system diseases, mesenchymal stem cell-derived extracellular vesicles may play a crucial role in promoting motor function recovery.…”
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    Mesenchymal stem cell-derived extracellular vesicles therapy in traumatic central nervous system diseases: a systematic review and meta-analysis
  14. 344934
    “…BACKGROUND: In a parallel-group, international, phase 3 study (ClinicalTrials.govNCT04762680), we evaluated prototype (D614) and Beta (B.1.351) variant recombinant spike protein booster vaccines with AS03-adjuvant (CoV2 preS dTM-AS03). …”
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    Safety and immunogenicity of a variant-adapted SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant as a booster in adults primed with authorized vaccines: a phase 3, parallel-group study
  15. 344935
    “…Given the advantages of the ITB-ACLR+ALLR—which include technically simple graft harvest/preparation/passage/fixation, optimization of both translational and rotational stability, preservation of both the dynamic knee extensor and flexor muscle groups, and relatively smaller bony tunnels—ongoing monitoring of graft rupture rates and PROs in the current cohort and future randomized, prospective clinical trials are warranted to assess the technique in methodologically rigorous, multicenter fashion.…”
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    Paper 37: Peri-Operative Complications, Safety, and Early Outcomes of a Novel ACL+ALL Reconstruction Technique using Iliotibial Band Autograft vs. Patellar Tendon ACL Reconstruction: A Retrospective Pilot Study of the SATURN (Skeletally-Mature ACLR Technique Using Reinforcement Network) Study Group
  16. 344936
    “…METHODS: A systematic review with meta-analysis of randomized controlled trials was conducted in healthy participants and participants with a lateral ankle sprain. …”
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    The effect of movement representation techniques on ankle function and performance in persons with or without a lateral ankle sprain: a systematic review and meta-analysis
  17. 344937
    “…Grants awarded to Zucker Hillside Hospital/Feinstein Institutes for Medical Research during the conduct of the brexanolone injection and zuranolone clinical trials (Sage Therapeutics), Consultant of: Sage Therapeutics, Inc., Brii Biosciences, Inc., and GH Research Ireland Limited, J. …”
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    Rapid improvements in MADRS with zuranolone in major depressive disorder and postpartum depression: results from the LANDSCAPE/NEST clinical development programmes
  18. 344938
    “…LIMITATIONS, REASONS FOR CAUTION: Of the 42 recommendations, none could be based on high-quality evidence and only four could be based on moderate-quality evidence, implicating that 95% of the recommendations are supported only by low-quality randomized controlled trials, observational data, professional experience, or consensus of the development group. …”
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    Good practice recommendations on add-ons in reproductive medicine
  19. 344939
    “…However, EUA was revoked in January 2023 due to identified resistance of Omicron lineage. Clinical trials about a new mAB for PrEP are continuing. Real-world data on the effectiveness of Evusheld may help develop strategies for the administration of new mAB. …”
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    493. ENDURANCE - EffectiveNess of Evusheld for COVID-19 Pre-exposUre PRophylAxis iN ImmunoCompromised PatiEnts – A Pilot Study
  20. 344940
    “…OBJECTIVES: The objectives of this systematic literature review and meta-analysis are to quantify BT intervention effects and to additionally characterize dose–response relationships of BT modalities (e.g., training period, training frequency) through the analysis of randomized controlled trials (RCTs) that could maximize improvements in balance performance in healthy community-dwelling older adults. …”
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    Effects of Balance Training on Balance Performance in Healthy Older Adults: A Systematic Review and Meta-analysis
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