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  1. 344961
    “…This study is registered with ClinicalTrials.gov, NCT04877496. FINDINGS: The final study population comprised 96 patients and 29 immunocompetent controls. …”
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    Humoral and cellular responses to mRNA vaccines against SARS-CoV-2 in patients with a history of CD20 B-cell-depleting therapy (RituxiVac): an investigator-initiated, single-centre, open-label study
  2. 344962
    por Holloway, Amelia, Mathews, Catherine
    Publicado 2021
    “…Despite their treatment benefits multiple adverse effects of TNF-alpha inhibition have been reported through clinical trials including a possible increased risk of malignancy. …”
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    O03 Continuation of golimumab (anti-TNF) in a patient with SpA and low-risk prostate cancer, what is the right decision?
  3. 344963
    “…The calculators were easy to use and applicable to both short- and long-course radiotherapy regimens, and they may be used to inform surveillance strategies and facilitate future clinical trials and statistical power calculations.…”
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    Development and Assessment of a Clinical Calculator for Estimating the Likelihood of Recurrence and Survival Among Patients With Locally Advanced Rectal Cancer Treated With Chemotherapy, Radiotherapy, and Surgery
  4. 344964
    “…IMPORTANCE: An international expert committee recently revised its recommendations on amino acid intake for very preterm infants, suggesting that more than 3.50 g/kg/d should be administered only to preterm infants in clinical trials. However, the optimal amino acid intake during the first week after birth in these infants is unknown. …”
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    Association Between Early Amino Acid Intake and Full-Scale IQ at Age 5 Years Among Infants Born at Less Than 30 Weeks’ Gestation
  5. 344965
    “…Eligible studies were retrospective or prospective comparative studies, randomized controlled trials, and case series with sample sizes of 10 patients or more reporting risk factors for cage subsidence or endplate injury after LLIF. …”
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    Poor Bone Quality, Multilevel Surgery, and Narrow and Tall Cages Are Associated with Intraoperative Endplate Injuries and Late-onset Cage Subsidence in Lateral Lumbar Interbody Fusion: A Systematic Review
  6. 344966
    “…INTRODUCTION Immunocompromised patients have been excluded from initial trials evaluating SARS-CoV-2 mRNA vaccines and there is a critical need to warrant vaccine efficacy in hematopoietic stem cell transplant (HSCT) recipients. …”
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    Antibody Response to 2-Dose Sars-Cov-2 mRNA Vaccine in Allogeneic Hematopoietic Cell Transplant Recipients
  7. 344967
    “…Of these, 3 considered the vaccines insufficiently tested in clinical trials; 2 explained that they have contraindications to the vaccinations, and 1 patient was afraid of adverse effects related to the vaccinations. 2 of these patients had university-level degrees, 1 had a high school diploma, and 1 received vocational education. 2 lived in towns with < 20 thousand inhabitants, 1 in a city of 20-50 thousand inhabitants and 1 in a city of 50-100.000 inhabitants. 3 were female, 1 was male. …”
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    Impact of the Covid-19 Pandemic on Quality of Life of Patients with CML
  8. 344968
    “…There is an urgent need for further evidence-based studies like clinical trials which are necessary to provide specific guidelines for use of therapeutic anticoagulants in patients with COVID-19 infection. …”
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    Clinical Outcomes in Critically-Ill Patients with COVID-19 Treated with Therapeutic Dose of Anticoagulants for Suspected Thromboembolism
  9. 344969
    “…Interim data from adaptive randomized control trials (ATTACC, REMAP-CAP, and ACTIV-4a) showed divergent results of therapeutic AC (TAC) versus usual care AC for the primary outcome of organ support free days in hospitalized COVID-19 patients. …”
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    Risk Stratification for Acute Arterial and Venous Thromboembolism using CHA (2)DS (2)-VASc Score in Hospitalized COVID-19 Patients: A Multicenter Study
  10. 344970
    “…However, patients with MM were not included in vaccination trials. Recent studies suggest that patients with compromised immune systems exhibit reduced antibody response to SARS-CoV-2 vaccination, and MM patients are often immunocompromised both due to MM itself and due to MM treatment. …”
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    Inadequate Sars-Cov-2 Vaccine Effectiveness in Patients with Multiple Myeloma: A Large Nationwide Veterans Affairs Study
  11. 344971
    “…Methods 162 coronavirus disease 2019 (COVID-19) convalescent plasma donors (CCD) and 40 healthy donor (HD) controls were enrolled prospectively in an IRB-approved protocol (Clinical Trials Number: NCT04360278) and provided written informed consent to participate in the study. …”
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    Longitudinal Transcriptional Analysis of Peripheral Blood Leukocytes in COVID Convalescent Donors
  12. 344972
    “…Although many patients with B-cell malignancies did not mount a robust response to full mRNA vaccine series, several patients demonstrated an antibody response to the booster vaccination. Clinical trials are needed to further understand who can benefit from a booster strategy as well as define the safety of the approach. …”
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    Sars-Cov-2 Antibody Levels in Blood Cancer Patients after a Third Sars-Cov-2 “Booster” Vaccination - Observational Data from the LLS National Registry
  13. 344973
    “…As the SARS-CoV-2 vaccines were developed and made available at an unprecedented rate, we are learning in real-time how specific vulnerable patient populations are affected, particularly as patients with cGVHD were largely excluded from clinical trials for the SARS-CoV-2 mRNA vaccines. Though the immunomodulatory mechanisms of the Pfizer and Moderna vaccines are poorly understood, societies such as ASH and ASTCT recommend that patients with cGVHD receive it. …”
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    Chronic Graft-Versus-Host Disease (cGVHD) Exacerbation after Sars-Cov-2 Covid Vaccination
  14. 344974
    “…This study also potentially suggests the protective benefits of COVID-19 vaccines as reported in prior randomized trials (Polack NEJM 2020). Further research is needed to confirm these findings in a larger vaccinated cohort assessing severe outcomes, hospitalization, and death, especially with future infection waves with contagious COVID-19 variants rapidly emerging. …”
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    Immature Platelets and Disease Severity in Patients Hospitalized with Acute COVID-19 Who Are Vaccinated Against COVID-19
  15. 344975
    “…This study is registered at ClinicalTrials.gov, NCT04786353. FINDINGS: 24 315 adolescents with a positive SARS-CoV-2 test (case group) and 97 257 matched controls were invited to participate. 3013 matched controls were excluded because of suspected SARS-CoV-2 infection. 6630 (27·3%) responded in the case group and 21 640 (22·3%) responded and were eligible to participate in the control group. …”
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    Long COVID symptoms in SARS-CoV-2-positive adolescents and matched controls (LongCOVIDKidsDK): a national, cross-sectional study
  16. 344976
    “…Unfortunately, no current treatment guidelines exist for RP due to a lack of randomised controlled trials but treatment is usually guided by the severity of manifestations in conjunction with trends from case series and expert opinion. …”
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    O28 A rare sight-threatening complication of a rare disease
  17. 344977
    “…He is Chair of TSC for STOP-OHSS and CERM trials and Chair of RCOG Academic Board 2018–2021. …”
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    Endometriosis classification systems: an international survey to map current knowledge and uptake(†)(‡)
  18. 344978
    “…RESULTS: The review summarizes evidence from 63 reports from 24 unique studies, which included 17 randomized controlled trials and 7 quasi‐experimental designs. In addition, 17 duplicate or summary reports were also located. …”
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    Interventions designed to improve financial capability: A systematic review
  19. 344979
    “…Article types included meta-analyses, systematic reviews, randomized controlled trials, cohort studies, case-control series, and case series for human subjects, published in English. …”
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    Vestibular Rehabilitation for Peripheral Vestibular Hypofunction: An Updated Clinical Practice Guideline From the Academy of Neurologic Physical Therapy of the American Physical Therapy Association
  20. 344980
    “…Excluded were (i) opinion papers or commentaries; (ii) studies that reported qualitative data; (iii) studies with samples mainly consisting of HCW, participants with confirmed or probable COVID-19 infection, hospitalized patients, or patients with a disease or condition; and (iv) clinical trials or intervention studies. To yield summary statistics, prevalence rates and sample sizes were pooled across studies. …”
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    The Impact of the COVID-19 Pandemic on the Mental Health of Older Adults
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