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  1. 345021
    “…Further prospective controlled trials are required to effectively study its efficacy. …”
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    Closed Incisional Negative Pressure Therapy Reduces Perineal Wound Complications After Abdominoperineal Resection
  2. 345022
    por Cortellini, Alessio, Tabernero, Josep, Mukherjee, Uma, Salazar, Ramon, Sureda, Anna, Maluquer, Clara, Ferrante, Daniela, Bower, Mark, Sharkey, Rachel, Mirallas, Oriol, Plaja, Andrea, Cucurull, Marc, Mesia, Ricard, Dalla Pria, Alessia, Newsom-Davis, Thomas, Van Hemelrijck, Mieke, Sita-Lumsden, Ailsa, Apthorp, Eleanor, Vincenzi, Bruno, Di Fazio, Giuseppina Rita, Tonini, Giuseppe, Pantano, Francesco, Bertuzzi, Alexia, Rossi, Sabrina, Brunet, Joan, Lambertini, Matteo, Pedrazzoli, Paolo, Biello, Federica, D'Avanzo, Francesca, Lee, Alvin J X, Shawe-Taylor, Marianne, Rogers, Lucy, Murphy, Cian, Cooper, Lee, Andaleeb, Ramis, Khalique, Saira, Bawany, Samira, Ahmed, Sarah, Carmona-García, M Carmen, Fort-Culillas, Roser, Liñan, Raquel, Zoratto, Federica, Rizzo, Gianpiero, Perachino, Marta, Doonga, Kris, Gaidano, Gianluca, Bruna, Riccardo, Patriarca, Andrea, Martinez-Vila, Clara, Pérez Criado, Ignacio, Giusti, Raffaele, Mazzoni, Francesca, Antonuzzo, Lorenzo, Santoro, Armando, Parisi, Alessandro, Queirolo, Paola, Aujayeb, Avinash, Rimassa, Lorenza, Diamantis, Nikolaos, Bertulli, Rossella, Fulgenzi, Claudia A M, D'Alessio, Antonio, Ruiz-Camps, Isabel, Saoudi-Gonzalez, Nadia, Garcia Illescas, David, Medina, Irene, Fox, Laura, Gennari, Alessandra, Aguilar-Company, Juan, Pinato, David J
    Publicado 2023
    “…This study is registered with ClinicalTrials.gov, NCT04393974. FINDINGS: At the follow-up update on June 20, 2022, 1909 eligible patients, evaluated after a median of 39 days (IQR 24–68) from COVID-19 diagnosis, were included (964 [50·7%] of 1902 patients with sex data were female and 938 [49·3%] were male). …”
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    SARS-CoV-2 omicron (B.1.1.529)-related COVID-19 sequelae in vaccinated and unvaccinated patients with cancer: results from the OnCovid registry
  3. 345023
    “…It is registered with ClinicalTrials.gov (NCT02771496). The cohort size and fine level of detail permit optimal algorithm development and allow the present study to consider whether anatomic, image-based, or demographic factors play a role in a lesion’s nonoperative healing capacity. …”
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    Paper 45: Which Osteochondritis Dissecans Subjects Will Heal Non-Operatively? An Application of Machine Learning Methods to the ROCK Cohort
  4. 345024
    por Xia, Zhongyang, Rajak, Rizwan
    Publicado 2023
    “…Interesting research directions include comparison of individual therapies in randomised controlled trials, assessing the effect of combination therapy as well as looking into the long-term efficacy and safety profiles of teriparatide and denosumab. …”
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    OA10 Pregnancy-associated osteoporosis - a rare subset of bone disease
  5. 345025
    “…When these agents have been trialed for PAO they have been discontinued prior to any subsequent pregnancies. …”
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    P01 An unusual case of pregnancy associated osteoporosis presenting with bilateral neck of femur fractures
  6. 345026
    por Goel, Nikita, Sandhu, Ravinder
    Publicado 2023
    “…Due to the paucity of cases worldwide and thus randomised controlled trials, there are limited data on management and long term follow up. …”
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    P09 A catastrophic decline: a significant skin rash in a patient presenting with catastrophic antiphospholipid syndrome
  7. 345027
    “…Our patient has been strongly engaged in the journey of his RA treatment, but unfortunately, the extent of his previous drug treatments and comorbidities means he is usually excluded from entering any drug trials, and this would similarly be applied to most patients who fall into the D2T RA category. …”
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    OA20 Combining B cell depletion and JAKi for difficult-to-treat rheumatoid arthritis
  8. 345028
    “…Given differences in study designs across trials, placebo treatment periods were excluded. Pts with mUFC >1.5 times the upper limit of normal (ULN) (LINC 2 and LINC 3) or mUFC >1.3 x ULN (LINC 4) were enrolled. …”
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    THU038 Osilodrostat Dosing In Cushing’s Disease: A Pooled Analysis Of The LINC Program
  9. 345029
    “…The HTA assessment further describes so-called complementary therapeutical approaches which have either not properly been studied in controlled clinical trials or which have been shown to be of no value for the treatment of atopic dermatitis. …”
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    Therapy of atopic eczema
  10. 345030
    “…OBJECTIVES: The aims of this systematic review and meta-analysis were to determine the general effects of RT on measures of muscle strength and morphology and to provide dose–response relationships of RT variables through an analysis of randomized controlled trials (RCTs) that could improve muscle strength and morphology in healthy old adults. …”
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    Dose–Response Relationships of Resistance Training in Healthy Old Adults: A Systematic Review and Meta-Analysis
  11. 345031
    “…METHODS: We searched theCochrane Database of Systematic Reviews (CDSR) on the Cochrane Library (CDSR 2016, Issue 1) for systematic reviews of randomised controlled trials (RCTs), after which we tracked any included reviews for updates, and tracked protocols in case of full review publication until an arbitrary cut‐off date of 21 March 2016 (CDSR 2016, Issue 3). …”
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    Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews
  12. 345032
    Publicado 2018
    “…We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. …”
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    Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
  13. 345033
    “…This study could lead to clinical translation by moving into larger animal studies and eventually clinical trials. The success of this study was determined by analyzing the results of echocardiography data on cardiac function (ejection fraction, fractional shortening, and left ventricle inner diameter) and assessment of histological staining on cardiac tissue (fibrotic tissue formation, infarct size, wall thinning, blood vessel cell counts, and vessel size quantification) after MI. …”
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    3395 An Injectable Sulfonated Reversible Thermal Gel for Controlled and Localized Delivery of Vascular Endothelial Growth Factor to Promote Cardiac Protection After a Myocardial Infarction
  14. 345034
    “…SEARCH METHODS: We undertook a comprehensive search of the following databases up to 30 July 2019: Cochrane Infectious Diseases Group Specialized Register; Central Register of Controlled Trials (CENTRAL), published in the Cochrane Library; MEDLINE (PubMed); Embase (OVID); Science Citation Index Expanded (SCI‐EXPANDED) and Conference Proceedings Citation Index‐Science (CPCI‐S), both in the Web of Science. …”
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    Rapid diagnostic tests for Plasmodium vivax malaria in endemic countries
  15. 345035
    “…Prospective multicenter trials are needed to further validate these findings.…”
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    Association Between Measurable Residual Disease in Patients With Intermediate-Risk Acute Myeloid Leukemia and First Remission, Treatment, and Outcomes
  16. 345036
    “…Four were randomised controlled trials (RCTs; N = 941) the remainder employed quasi‐experimental designs with parallel cohorts. …”
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    Family group decision‐making for children at risk of abuse or neglect: A systematic review
  17. 345037
    “…Included evaluations were conducted using both randomized (n = 45; i.e., randomized controlled trials/RCTs) and nonrandomized (n = 44; i.e., quasi‐experimental designs with before/after measures; BA/EC) methodologies. …”
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    Effectiveness of school‐based programs to reduce bullying perpetration and victimization: An updated systematic review and meta‐analysis
  18. 345038
    “…Management of CRMO encompasses a variety of treatments, including NSAIDs, steroids, DMARDs and bisphosphonates largely based upon smaller trials. Due to ongoing symptoms despite conventional synthetic and biologic DMARDs, in this patient IV pamidronate treatment was commenced. …”
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    O13 A case of chronic recurrent multifocal osteomyelitis
  19. 345039
    “…Introduction: Randomized trials demonstrated ~95% efficacy of SARS-CoV-2 spike messenger RNA (mRNA) vaccines. …”
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    Assessment of Serology after Sars-Cov-2 Vaccine in Allogeneic HCT Recipients
  20. 345040
    “…Whether COVID-19 vaccinations may contribute to DVT risk more generally (outside of VITT) has not been well studied outside of the initial clinical trials. Aims: Evaluate trends in DVT diagnosis before and after COVID-19 vaccination Methods: Vaccinated patients ≥ 18 years between 11/6/2020 through 6/1/2021 were analyzed using electronic medical records across the Mayo Clinic enterprise. …”
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    Deep Vein Thrombosis after COVID-19 Vaccinations
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