Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)

por Esserman, Laura J., Berry, Donald A., Cheang, Maggie C. U., Yau, Christina, Perou, Charles M., Carey, Lisa, DeMichele, Angela, Gray, Joe W., Conway-Dorsey, Kathleen, Lenburg, Marc E., Buxton, Meredith B., Davis, Sarah E., van’t Veer, Laura J., Hudis, Clifford, Chin, Koei, Wolf, Denise, Krontiras, Helen, Montgomery, Leslie, Tripathy, Debu, Lehman, Constance, Liu, Minetta C., Olopade, Olufunmilayo I., Rugo, Hope S., Carpenter, John T., Livasy, Chad, Dressler, Lynn, Chhieng, David, Singh, Baljit, Mies, Carolyn, Rabban, Joseph, Chen, Yunni-Yi, Giri, Dilip, Au, Alfred, Hylton, Nola
Publicado 2011

TOPS: an internet-based system to prevent healthy subjects from over-volunteering for clinical trials

por Boyce, M., Walther, M., Nentwich, H., Kirk, J., Smith, S., Warrington, S.
Publicado 2012

Changes in Bone Turnover and Bone Loss in HIV-Infected Patients Changing Treatment to Tenofovir-Emtricitabine or Abacavir-Lamivudine

por Haskelberg, Hila, Hoy, Jennifer F., Amin, Janaki, Ebeling, Peter R., Emery, Sean, Carr, Andrew, STEAL Study Group
Publicado 2012

A phase II study of afatinib (BIBW 2992), an irreversible ErbB family blocker, in patients with HER2-positive metastatic breast cancer progressing after trastuzumab

por Lin, Nancy U., Winer, Eric P., Wheatley, Duncan, Carey, Lisa A., Houston, Stephen, Mendelson, David, Munster, Pamela, Frakes, Laurie, Kelly, Steve, Garcia, Agustin A., Cleator, Susan, Uttenreuther-Fischer, Martina, Jones, Hilary, Wind, Sven, Vinisko, Richard, Hickish, Tamas
Publicado 2012

25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1

por Amir, Eitan, Cecchini, Reena S., Ganz, Patricia A., Costantino, Joseph P., Beddows, Samantha, Hood, Nicola, Goodwin, Pamela J.
Publicado 2012

An abnormal screening mammogram causes more anxiety than a palpable lump in benign breast disease

por Keyzer-Dekker, C. M. G., van Esch, L., de Vries, J., Ernst, M. F., Nieuwenhuijzen, G. A. P., Roukema, J. A., van der Steeg, A. F. W.
Publicado 2012

Quality of life in relation to tamoxifen or exemestane treatment in postmenopausal breast cancer patients: a Tamoxifen Exemestane Adjuvant Multinational (TEAM) Trial side study

por van Nes, J. G. H., Fontein, D. B. Y., Hille, E. T. M., Voskuil, D. W., van Leeuwen, F. E., de Haes, J. C. J. M., Putter, H., Seynaeve, C., Nortier, J. W. R., van de Velde, C. J. H.
Publicado 2012

LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial

por Zambrowicz, B, Freiman, J, Brown, P M, Frazier, K S, Turnage, A, Bronner, J, Ruff, D, Shadoan, M, Banks, P, Mseeh, F, Rawlins, D B, Goodwin, N C, Mabon, R, Harrison, B A, Wilson, A, Sands, A, Powell, D R
Publicado 2012

Sentinel lymph node biopsy of the internal mammary chain in breast cancer

por Postma, E. L., van Wieringen, S., Hobbelink, M. G., Verkooijen, H. M., van den Bongard, H. J. G. D., Borel Rinkes, I. H. M., Witkamp, A. J.
Publicado 2012

Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide

por Gjerde, Jennifer, Gandini, Sara, Guerrieri-Gonzaga, Aliana, Haugan Moi, Line L., Aristarco, Valentina, Mellgren, Gunnar, DeCensi, Andrea, Lien, Ernst A.
Publicado 2012

A phase II trial to assess efficacy and safety of afatinib in extensively pretreated patients with HER2-negative metastatic breast cancer

por Schuler, Martin, Awada, Ahmad, Harter, Philipp, Canon, Jean Luc, Possinger, Kurt, Schmidt, Marcus, De Grève, Jacques, Neven, Patrick, Dirix, Luc, Jonat, Walter, Beckmann, Matthias W., Schütte, Jochen, Fasching, Peter A., Gottschalk, Nina, Besse-Hammer, Tatiana, Fleischer, Frank, Wind, Sven, Uttenreuther-Fischer, Martina, Piccart, Martine, Harbeck, Nadia
Publicado 2012

Phase 1b dose-finding study of motesanib with docetaxel or paclitaxel in patients with metastatic breast cancer

por De Boer, Richard H., Kotasek, Dusan, White, Shane, Koczwara, Bogda, Mainwaring, Paul, Chan, Arlene, Melara, Rebeca, Ye, Yining, Adewoye, Adeboye H., Sikorski, Robert, Kaufman, Peter A.
Publicado 2012

Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole

por Lunardi, G., Piccioli, P., Bruzzi, P., Notaro, R., Lastraioli, S., Serra, M., Marroni, P., Bighin, C., Mansutti, M., Puglisi, F., Porpiglia, M., Ponzone, R., Bisagni, G., Garrone, O., Cavazzini, G., Clavarezza, M., Del Mastro, L.
Publicado 2012

An angiotensin II receptor blocker–calcium channel blocker combination prevents cardiovascular events in elderly high-risk hypertensive patients with chronic kidney disease better...

por Kim-Mitsuyama, Shokei, Ogawa, Hisao, Matsui, Kunihiko, Jinnouchi, Tomio, Jinnouchi, Hideaki, Arakawa, Kikuo
Publicado 2013

A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer

por Ma, Cynthia X., Ellis, Matthew J. C., Petroni, Gina R., Guo, Zhanfang, Cai, Shi-rong, Ryan, Christine E., Craig Lockhart, A., Naughton, Michael J., Pluard, Timothy J., Brenin, Christiana M., Picus, Joel, Creekmore, Allison N., Mwandoro, Tibu, Yarde, Erin R., Reed, Jerry, Ebbert, Mark, Bernard, Philip S., Watson, Mark, Doyle, Laurence A., Dancey, Janet, Piwnica-Worms, Helen, Fracasso, Paula M.
Publicado 2012

A randomized phase II study of lapatinib + pazopanib versus lapatinib in patients with HER2+ inflammatory breast cancer

por Cristofanilli, Massimo, Johnston, Stephen R. D., Manikhas, Alexey, Gomez, Henry L., Gladkov, Oleg, Shao, Zhimin, Safina, Sufia, Blackwell, Kimberly L., Alvarez, Ricardo H., Rubin, Stephen D., Ranganathan, Sulabha, Redhu, Suman, Trudeau, Maureen E.
Publicado 2012

Phase II study evaluating lapatinib in combination with nab-paclitaxel in HER2-overexpressing metastatic breast cancer patients who have received no more than one prior chemotherap...

por Yardley, Denise A., Hart, Lowell, Bosserman, Linda, Salleh, Mansoor N., Waterhouse, David M., Hagan, Maura K., Richards, Paul, DeSilvio, Michelle L., Mahoney, Janine M., Nagarwala, Yasir
Publicado 2012

Pharmacokinetics of transdermal buprenorphine patch in the elderly

por Al-Tawil, Nabil, Odar-Cederlöf, Ingegerd, Berggren, Anna-Carin, Johnson, Helen E., Persson, Jan
Publicado 2012

Design and Rationale of the PRAGUE‐12 Trial: A Large, Prospective, Randomized, Multicenter Trial That Compares Cardiac Surgery With Left Atrial Surgical Ablation With Cardiac Surgery Without Ablation in Patients With Coronary and/or Valvular Heart Disease Plus Atrial Fibrillation

por Straka, Zbyněk, Budera, Petr, Osmančík, Pavel, Vaněk, Tomáš, Hulman, Michal, Šmíd, Michal, Malý, Marek, Widimský, Petr
Publicado 2012

Pharmacokinetic and pharmacodynamic effects of comedication of clopidogrel and dabigatran etexilate in healthy male volunteers

por Härtter, Sebastian, Sennewald, Regina, Schepers, Cornelia, Baumann, Sybille, Fritsch, Holger, Friedman, Jeffrey
Publicado 2012