Pharmacokinetics of dolutegravir in HIV-seronegative subjects with severe renal impairment

por Weller, Stephen, Borland, Julie, Chen, Shuguang, Johnson, Mark, Savina, Paul, Wynne, Brian, Wajima, Toshihiro, Peppercorn, Amanda F., Piscitelli, Stephen C.
Publicado 2013

Comparative efficacy of everolimus plus exemestane versus fulvestrant for hormone-receptor-positive advanced breast cancer following progression/recurrence after endocrine therapy:...

por Bachelot, Thomas, McCool, Rachael, Duffy, Steven, Glanville, Julie, Varley, Danielle, Fleetwood, Kelly, Zhang, Jie, Jerusalem, Guy
Publicado 2013

A phase II study of docetaxel and vinorelbine plus filgrastim for HER-2 negative, stage IV breast cancer: SWOG S0102

por Gralow, Julie R., Barlow, William E., Lew, Danika, Dammann, Kim, Somlo, George, Rinn, Kristine J., Vogel, Stanley J., Wong, Lucas, Livingston, Robert B., Hortobagyi, Gabriel N.
Publicado 2013

Effect of A Reduction in glomerular filtration rate after NEphrectomy on arterial STiffness and central hemodynamics: Rationale and design of the EARNEST study()

por Moody, William E., Tomlinson, Laurie A., Ferro, Charles J., Steeds, Richard P., Mark, Patrick B., Zehnder, Daniel, Tomson, Charles R., Cockcroft, John R., Wilkinson, Ian B., Townend, Jonathan N.
Publicado 2014

Everolimus plus exemestane as first-line therapy in HR(+), HER2(−) advanced breast cancer in BOLERO-2

por Beck, J. Thaddeus, Hortobagyi, Gabriel N., Campone, Mario, Lebrun, Fabienne, Deleu, Ines, Rugo, Hope S., Pistilli, Barbara, Masuda, Norikazu, Hart, Lowell, Melichar, Bohuslav, Dakhil, Shaker, Geberth, Matthias, Nunzi, Martina, Heng, Daniel Y. C., Brechenmacher, Thomas, El-Hashimy, Mona, Douma, Shyanne, Ringeisen, Francois, Piccart, Martine
Publicado 2013

Prospective evaluation of the conversion rate in the receptor status between primary breast cancer and metastasis: results from the GEICAM 2009-03 ConvertHER study

por de Dueñas, Eduardo Martínez, Hernández, Ana Lluch, Zotano, Ángel Guerrero, Carrión, Ramón María Pérez, López-Muñiz, José Ignacio Chacón, Novoa, Silvia Antolín, Rodríguez, Ángela López, Fidalgo, José Alejandro Pérez, Lozano, Jaime Ferrer, Gasión, Octavio Burgués, Carrascal, Eva Carrasco, Capilla, Andrés Hernando, López-Barajas, Isabel Blancas, Mateu, Montserrat Muñoz, de Ceballos Reyna, María Helena López, Ferrando, Amparo Oltra, Jañez, Noelia Martínez, Ballerini, Vicente Carañana, Torres, Antonio Antón, Catalán, Gustavo, Sáenz, José Ángel García, Menjón, Salomón, González-Angulo, Ana María
Publicado 2014

A phase II, randomized, multicenter study evaluating the combination of lapatinib and vinorelbine in women with ErbB2 overexpressing metastatic breast cancer

por Janni, Wolfgang, Sarosiek, Tomasz, Karaszewska, Boguslawa, Pikiel, Joanna, Staroslawska, Elzbieta, Potemski, Piotr, Salat, Christoph, Brain, Etienne, Caglevic, Christian, Briggs, Kathryn, DeSilvio, Michelle, Marini, Luca, Papadimitriou, Christos
Publicado 2014

Mammographic screening detects low-risk tumor biology breast cancers

por Drukker, C. A., Schmidt, M. K., Rutgers, E. J. T., Cardoso, F., Kerlikowske, K., Esserman, L. J., van Leeuwen, F. E., Pijnappel, R. M., Slaets, L., Bogaerts, J., van’t Veer, L. J.
Publicado 2014

Long-term prognosis of early-onset breast cancer in a population-based cohort with a known BRCA1/2 mutation status

por Nilsson, Martin P., Hartman, Linda, Idvall, Ingrid, Kristoffersson, Ulf, Johannsson, Oskar T., Loman, Niklas
Publicado 2014

Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time?

por Esserman, L. J., Alvarado, M. D., Howe, R. J., Mohan, A. J., Harrison, B., Park, C., O’Donoghue, C., Ozanne, E. M.
Publicado 2014

The clinical utility of genetic testing in breast cancer kindreds: a prospective study in families without a demonstrable BRCA mutation

por Møller, Pål, Stormorken, Astrid, Holmen, Marit Muri, Hagen, Anne Irene, Vabø, Anita, Mæhle, Lovise
Publicado 2014

A phase II, multicentre trial evaluating the efficacy of de-escalated bisphosphonate therapy in metastatic breast cancer patients at low-risk of skeletal-related events

por Addison, Christina L., Bouganim, Nathaniel, Hilton, John, Vandermeer, Lisa, Dent, Susan, Amir, Eitan, Hopkins, Sean, Kuchuk, Iryna, Segal, Roanne, Song, Xinni, Gertler, Stan, Mazzarello, Sasha, Dranitsaris, George, Ooi, Daylily, Pond, Gregory, Clemons, Mark
Publicado 2014

Effects of combining azilsartan medoxomil with amlodipine in patients with stage 2 hypertension

por Weber, Michael A., White, William B., Sica, Domenic, Bakris, George L., Cao, Charlie, Roberts, Andrew, Kupfer, Stuart
Publicado 2014

Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control

por Kohan, Donald E, Fioretto, Paola, Tang, Weihua, List, James F
Publicado 2014

Pharmacokinetics and pharmacodynamics of oral tolvaptan in patients with varying degrees of renal function

por Shoaf, Susan E, Bricmont, Patricia, Mallikaarjun, Suresh
Publicado 2014

Effect of azilsartan versus candesartan on morning blood pressure surges in Japanese patients with essential hypertension

por Rakugi, Hiromi, Kario, Kazuomi, Enya, Kazuaki, Sugiura, Kenkichi, Ikeda, Yoshinori
Publicado 2014

Ultra-low-dose estriol and Lactobacillus acidophilus vaginal tablets (Gynoflor(®)) for vaginal atrophy in postmenopausal breast cancer patients on aromatase inhibitors: pharmacokin...

por Donders, Gilbert, Neven, Patrick, Moegele, Maximilian, Lintermans, Anneleen, Bellen, Gert, Prasauskas, Valdas, Grob, Philipp, Ortmann, Olaf, Buchholz, Stefan
Publicado 2014

A phase IIa, nonrandomized study of radium-223 dichloride in advanced breast cancer patients with bone-dominant disease

por Coleman, Robert, Aksnes, Anne-Kirsti, Naume, Bjørn, Garcia, Camilo, Jerusalem, Guy, Piccart, Martine, Vobecky, Nancy, Thuresson, Marcus, Flamen, Patrick
Publicado 2014

Optimized outcome prediction in breast cancer by combining the 70-gene signature with clinical risk prediction algorithms

por Drukker, C. A., Nijenhuis, M. V., Bueno-de-Mesquita, J. M., Retèl, V. P., van Harten, W. H., van Tinteren, H., Wesseling, J., Schmidt, M. K., van’t Veer, L. J., Sonke, G. S., Rutgers, E. J. T., van de Vijver, M. J., Linn, S. C.
Publicado 2014

Phase 2 study of eribulin mesylate as first-line therapy for locally recurrent or metastatic human epidermal growth factor receptor 2-negative breast cancer

por McIntyre, Kristi, O’Shaughnessy, Joyce, Schwartzberg, Lee, Glück, Stefan, Berrak, Erhan, Song, James X., Cox, David, Vahdat, Linda T.
Publicado 2014