A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma – A final report

por Gnekow, Astrid K., Walker, David A., Kandels, Daniela, Picton, Susan, Giorgio Perilongo, Grill, Jacques, Stokland, Tore, Sandstrom, Per Eric, Warmuth-Metz, Monika, Pietsch, Torsten, Giangaspero, Felice, Schmidt, René, Faldum, Andreas, Kilmartin, Denise, De Paoli, Angela, De Salvo, Gian Luca
Publicado 2017

Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial

por Cortés, Javier, Rugo, Hope S., Awada, Ahmad, Twelves, Chris, Perez, Edith A., Im, Seock–Ah, Gómez-Pardo, Patricia, Schwartzberg, Lee S., Diéras, Veronique, Yardley, Denise A., Potter, David A., Mailliez, Audrey, Moreno-Aspitia, Alvaro, Ahn, Jin-Seok, Zhao, Carol, Hoch, Ute, Tagliaferri, Mary, Hannah, Alison L., O’Shaughnessy, Joyce
Publicado 2017

IRIS study: a phase II study of the steroid sulfatase inhibitor Irosustat when added to an aromatase inhibitor in ER-positive breast cancer patients

por Palmieri, Carlo, Stein, Rob C., Liu, Xinxue, Hudson, Emma, Nicholas, Hanna, Sasano, Hironobu, Guestini, Fouzia, Holcombe, Chris, Barrett, Sophie, Kenny, Laura, Reed, Sadie, Lim, Adrian, Hayward, Larry, Howell, Sacha, Coombes, R. Charles
Publicado 2017

The efficacy of lymphaticovenular anastomosis in breast cancer-related lymphedema

por Winters, H., Tielemans, H. J. P., Hameeteman, M., Paulus, V. A. A., Beurskens, C. H., Slater, N. J., Ulrich, D. J. O.
Publicado 2017

Development of a Ki-67-based clinical trial assay for neoadjuvant endocrine therapy response monitoring in breast cancer

por Goncalves, Rodrigo, DeSchryver, Katherine, Ma, Cynthia, Tao, Yu, Hoog, Jeremy, Cheang, Maggie, Crouch, Erika, Dahiya, Neha, Sanati, Souzan, Barnes, Michael, Sarian, Luis Otávio Zanatta, Olson, John, Allred, Donald Craig, Ellis, Matthew J.
Publicado 2017

Probing oral anticoagulation in patients with atrial high rate episodes: Rationale and design of the Non–vitamin K antagonist Oral anticoagulants in patients with Atrial High rate episodes (NOAH–AFNET 6) trial

por Kirchhof, Paulus, Blank, Benjamin F., Calvert, Melanie, Camm, A. John, Chlouverakis, Gregory, Diener, Hans-Christoph, Goette, Andreas, Huening, Andrea, Lip, Gregory Y.H., Simantirakis, Emmanuel, Vardas, Panos
Publicado 2017

Carboplatin versus two doses of cisplatin in combination with gemcitabine in the treatment of advanced non-small-cell lung cancer: Results from a British Thoracic Oncology Group randomised phase III trial

por Ferry, David, Billingham, Lucinda, Jarrett, Hugh, Dunlop, David, Woll, Penella J., Nicolson, Marianne, Shah, Riyaz, Thompson, Joyce, Spicer, James, Muthukumar, D., Skailes, Geraldine, Leonard, Pauline, Chetiyawardana, A.D., Wells, Paula, Lewanski, Conrad, Crosse, Barbara, Hill, Michelle, Gaunt, Piers, O'Byrne, Kenneth
Publicado 2017

Improved survival for sequentially as opposed to concurrently delivered neoadjuvant chemotherapy in non-metastatic breast cancer

por Vriens, B. E. P. J., Vriens, I. J. H., Aarts, M. J. B., van Gastel, S. M., van den Berkmortel, F. W. P. J., Smilde, T. J., van Warmerdam, L. J. C., van Spronsen, D. J., Peer, P. G. M., de Boer, M., Tjan-Heijnen, V. C. G.
Publicado 2017

Different outcome in node-positive breast cancer patients found by axillary ultrasound or sentinel node procedure

por Verheuvel, Nicole C., Voogd, Adri C., Tjan-Heijnen, Vivianne C. G., Siesling, S., Roumen, Rudi M. H.
Publicado 2017

A randomized, multicenter, open-label, blinded end point trial comparing the effects of spironolactone to chlorthalidone on left ventricular mass in patients with early-stage chronic kidney disease: Rationale and design of the SPIRO-CKD trial

por Hayer, Manvir K., Edwards, Nicola C., Slinn, Gemma, Moody, William E., Steeds, Rick P., Ferro, Charles J., Price, Anna M., Andujar, Cecilio, Dutton, Mary, Webster, Rachel, Webb, David J., Semple, Scott, MacIntyre, Iain, Melville, Vanessa, Wilkinson, Ian B., Hiemstra, Thomas F., Wheeler, David C., Herrey, Anna, Grant, Margaret, Mehta, Samir, Ives, Natalie, Townend, Jonathan N.
Publicado 2017

Rationale and design of the AdaptResponse trial: a prospective randomized study of cardiac resynchronization therapy with preferential adaptive left ventricular‐only pacing

por Filippatos, Gerasimos, Birnie, David, Gold, Michael R., Gerritse, Bart, Hersi, Ahmad, Jacobs, Sandra, Kusano, Kengo, Leclercq, Christophe, Mullens, Wilfried, Wilkoff, Bruce L.
Publicado 2017

Systematic review and network meta-analysis comparing palbociclib with chemotherapy agents for the treatment of postmenopausal women with HR-positive and HER2-negative advanced/met...

por Wilson, Florence R., Varu, Abhishek, Mitra, Debanjali, Cameron, Chris, Iyer, Shrividya
Publicado 2017

IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer

por Palmieri, Carlo, Szydlo, Richard, Miller, Marie, Barker, Laura, Patel, Neva H., Sasano, Hironobu, Barwick, Tara, Tam, Henry, Hadjiminas, Dimitri, Lee, Jasmin, Shaaban, Abeer, Nicholas, Hanna, Coombes, R. Charles, Kenny, Laura M.
Publicado 2017

Prognostic and predictive importance of the estrogen receptor coactivator AIB1 in a randomized trial comparing adjuvant letrozole and tamoxifen therapy in postmenopausal breast cancer: the Danish cohort of BIG 1-98

por Alkner, S., Jensen, M.-B., Rasmussen, B. B., Bendahl, P.-O., Fernö, M., Rydén, L., Mouridsen, H.
Publicado 2017

Cross-cultural comparison of breast cancer patients’ Quality of Life in the Netherlands and Japan

por Fischer, M. J., Inoue, K., Matsuda, A., Kroep, J. R., Nagai, S., Tozuka, K., Momiyama, M., Weijl, N. I., Langemeijer-Bosman, D., Ramai, S. R. S., Nortier, J. W. R., Putter, H., Yamaoka, K., Kubota, K., Kobayashi, K., Kaptein, A. A.
Publicado 2017

Utilization of bioimpedance spectroscopy in the prevention of chronic breast cancer-related lymphedema

por Kaufman, David I., Shah, Chirag, Vicini, Frank A., Rizzi, Marisa
Publicado 2017

Analysis of integrated clinical trial protocols in early phases of medicinal product development

por Fruhner, Kevin, Hartmann, Gunther, Sudhop, Thomas
Publicado 2017

Who is willing to participate in low-risk pragmatic clinical trials without consent?

por Dal-Ré, Rafael, Carcas, Antonio J., Carné, Xavier
Publicado 2017

Rationale, design, and baseline characteristics of the CLARIFY registry of outpatients with stable coronary artery disease

por Sorbets, Emmanuel, Greenlaw, Nicola, Ferrari, Roberto, Ford, Ian, Fox, Kim M., Tardif, Jean‐Claude, Tendera, Michal, Steg, Philippe Gabriel
Publicado 2017

Off-pump versus On-pump Coronary Artery Bypass Grafting in Frail Patients: Study Protocol for the FRAGILE Multicenter Randomized Controlled Trial

por Mejía, Omar Asdrúbal Vilca, Sá, Michel Pompeu Barros Oliveira, Deininger, Maurilio Onofre, Dallan, Luís Roberto Palma, Segalote, Rodrigo Coelho, de Oliveira, Marco Antonio Praça, Atik, Fernando Antibas, dos Santos, Magaly Arrais, Silva, Pedro Gabriel Melo de Barros e, Milani, Rodrigo Mussi, Hueb, Alexandre Ciappina, Monteiro, Rosangela, Lima, Ricardo Carvalho, Lisboa, Luiz Augusto Ferreira, Dallan, Luís Alberto Oliveira, Puskas, John, Jatene, Fabio Biscegli
Publicado 2017