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1141The Cessation in Pregnancy Incentives Trial (CPIT): study protocol for a randomized controlled trialpor Tappin, David M, Bauld, Linda, Tannahill, Carol, de Caestecker, Linda, Radley, Andrew, McConnachie, Alex, Boyd, Kathleen, Briggs, Andrew, Grant, Liz, Cameron, Alan, MacAskill, Susan, Sinclair, Lesley, Friel, Brenda, Coleman, Tim“…TRIAL REGISTRATION: Current Controlled Trials ISRCTN87508788…”
Publicado 2012
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1142por Hata, Jun, Arima, Hisatomi, Zoungas, Sophia, Fulcher, Greg, Pollock, Carol, Adams, Mark, Watson, John, Joshi, Rohina, Kengne, Andre Pascal, Ninomiya, Toshiharu, Anderson, Craig, Woodward, Mark, Patel, Anushka, Mancia, Giuseppe, Poulter, Neil, MacMahon, Stephen, Chalmers, John, Neal, Bruce“…BACKGROUND: Endpoint adjudication committees (EPAC) are widely used in clinical trials. The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial (Trial registration: ClinicalTrials.gov NCT00145925). …”
Publicado 2013
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1143por Ross, Joseph S, Tse, Tony, Zarin, Deborah A, Xu, Hui, Zhou, Lei, Krumholz, Harlan M“…Design Cross sectional analysis. Setting Clinical trials funded by NIH and registered within ClinicalTrials.gov (clinicaltrials.gov), a trial registry and results database maintained by the US National Library of Medicine, after 30 September 2005 and updated as having been completed by 31 December 2008, allowing at least 30 months for publication after completion of the trial. …”
Publicado 2012
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1144por Kaur, Geetinder, Hutchison, Iain, Mehanna, Hisham, Williamson, Paula, Shaw, Richard, Tudur Smith, Catrin“…OBJECTIVES: Many randomised trials in surgery suffer from recruitment rates that lag behind projected targets. …”
Publicado 2013
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1145“…The objectives of this review are to assess the current state of hypertonic saline as a prehospital resuscitation fluid in hypotensive trauma patients, particularly after the 3 major Resuscitation Outcomes Consortium trauma trials in the US and Canada were halted due to futility. …”
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1146por Pagoto, Sherry, Schneider, Kristin L., Whited, Matthew C., Oleski, Jessica L., Merriam, Phillip, Appelhans, Bradley, Ma, Yunsheng, Olendzki, Barbara, Waring, Molly E., Busch, Andrew M., Lemon, Stephenie, Ockene, Ira, Crawford, Sybil“…DESIGN: In a randomized controlled trial, obese women with major depressive disorder (N=161, mean age=45.9 [SD: 10.8] years) were randomized to brief behavior therapy for depression treatment followed by a lifestyle intervention (BA) or a lifestyle intervention only (LI). …”
Publicado 2013
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1147por Orban de Xivry, Jean-JacquesEnlace del recurso
Publicado 2013
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1149“…Congruency effects in distracter interference tasks are often smaller after incongruent trials than after congruent trials. However, the sources of such congruency sequence effects (CSEs) are controversial. …”
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1150por Goswami, Neela D., Pfeiffer, Christopher D., Horton, John R., Chiswell, Karen, Tasneem, Asba, Tsalik, Ephraim L.“…The ClinicalTrials.gov registry offers an opportunity to evaluate the ID clinical trials portfolio. …”
Publicado 2013
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1151por Lund, Karen, Vase, Lene, Petersen, Gitte L., Jensen, Troels S., Finnerup, Nanna B.“…BACKGROUND: It is an inherent assumption in randomised controlled trials that the drug effect can be estimated by subtracting the response during placebo from the response during active drug treatment. …”
Publicado 2014
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1152por Morrish, Alicia T, Hawley, Carmel M, Johnson, David W, Badve, Sunil V, Perkovic, Vlado, Reidlinger, Donna M, Cass, Alan“…To address this deficiency, the Australasian Kidney Trials Network, a Collaborative Research Group, was formed in 2005. …”
Publicado 2014
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1155Publicado 2014“…Objective To investigate the planning of subgroup analyses in protocols of randomised controlled trials and the agreement with corresponding full journal publications. …”
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1156“…We review the results of the first large-scale randomized trial of this treatment. RECENT FINDINGS: The trial to assess chelation therapy was a $30 million National Institutes of Health-funded study of the safety and efficacy of EDTA-based chelation infusions in 1708 post-myocardial infarction (MI) patients. …”
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1157“…The 295 unique clinical trials identified employed 447 investigational agents, with 30% of 154 acute migraine trials and 11% of 141 migraine prophylaxis trials testing combinations of agents. …”
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1158por Succop, Stacey M., MacQueen, Kathleen M., van Loggerenberg, Francois, Majola, Nelisile, Karim, Quarraisha Abdool, Karim, Salim S. Abdool“…Disclosure, or open communication, by female microbicide trial participants of their trial participation and use of an investigational HIV prevention drug to a sexual partner may affect participants' trial product usage behavior and contribute to poor adherence. …”
Publicado 2014
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1159por Scherer, Roberta W, Formby, Craig, Gold, Susan, Erdman, Sue, Rodhe, Charles, Carlson, Michele, Shade, Dave, Tucker, Melanie, Sensinger, Lee McCaffrey, Hughes, Gordon, Conley, George S, Downey, Naomi, Eades, Cynthia, Jylkka, Margaret, Haber-Perez, Ada, Harper, Courtney, Russell, Shoshannah Kantor, Sierra-Irizarry, Benigno, Sullivan, Mark“…The Tinnitus Retraining Therapy Trial (TRTT) is a randomized, double-blind, placebo-controlled, multicenter trial for individuals with intolerable tinnitus. …”
Publicado 2014
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1160Placebo-controlled clinical trials: how trial documents justify the use of randomisation and placebo“…BACKGROUND: Randomised clinical trials (RCTs) involve procedures such as randomisation, blinding, and placebo use, which are not part of standard medical care. …”
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