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  1. 1201
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    The RECOVERY trial: cardiovascular implications of a large, simple randomized trial in COVID-19
  2. 1202
    “…BACKGROUND: Although widely used in treating severe abdominal trauma, damage control laparotomy (DCL) has not been assessed in any randomized controlled trial. We conducted a pilot trial among patients for whom our surgeons had equipoise and hypothesized that definitive laparotomy (DEF) would reduce major abdominal complications (MAC) or death within 30 days compared with DCL. …”
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    Damage control laparotomy in trauma: a pilot randomized controlled trial. The DCL trial
  3. 1203
    “…Objective: This study aimed to analyze the characteristics and reasons of early discontinuation of obsessive-compulsive disorder (OCD) trials registered on ClinicalTrials.gov. Methods: OCD trials and relevant publications were searched on ClinicalTrials.gov and PubMed, respectively. …”
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    Characteristic and Early Discontinuation of Obsessive-Compulsive Disorder Trials Registered on ClinicalTrials.gov
  4. 1204
    “…BACKGROUND/AIMS: Participants are integral to the success of any clinical research study, yet participant recruitment into clinical trials poses ongoing and complex challenges. It is widely accepted and recognised that clinical trial sites often find it difficult to meet recruitment goals, both in terms of accrual targets and timelines. …”
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    Clinical trials site recruitment optimisation: Guidance from Clinical Trials: Impact and Quality
  5. 1205
    “…DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study evaluated eligible trials registered in ClinicalTrials.gov, an online clinical trials registry, from July 1, 2005, to June 30, 2016. …”
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    Comparison of Publication of Pediatric Probiotic vs Antibiotic Trials Registered on ClinicalTrials.gov
  6. 1206
    por Zhang, Pengfei, Do, Thien Phu
    Publicado 2021
    “…Background and Objective: ClinicalTrials.gov is a centralized venue for monitoring clinical research and allows access to information on publicly and privately funded studies. …”
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    Locating Organizations and Their Methods in Registrations of Clinical Migraine Trials: Analysis of ClinicalTrials.gov
  7. 1207
    “…DISCUSSION: TWIST aims to determine the effect and safety of thrombolytic treatment with tenecteplase in patients with wake-up ischemic stroke selected by non-contrast CT. TRIAL REGISTRATION: ClinicalTrials.gov NCT03181360. …”
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    Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial
  8. 1208
    “…The reliability of the information in trial registries is uncertain. OBJECTIVE: To assess the reliability of information across registries for trials with multiple registrations. …”
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    Reliability of Trial Information Across Registries for Trials With Multiple Registrations: A Systematic Review
  9. 1209
    “…Previous studies have shown that current movement is influenced by the previous movement, which is known as the previous trial effect. In this study, we investigated the influence of the inter-trial interval, movement observation, and hand dominance on the previous trial effect of the non-target discrete movement. …”
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    Influence of the Inter-Trial Interval, Movement Observation, and Hand Dominance on the Previous Trial Effect
  10. 1210
    “…We describe the concepts and design of the SIOP-E high-risk medulloblastoma clinical trial (SIOP-HR-MB), the first international, biomarker-driven, randomised clinical trial for high-risk medulloblastoma. …”
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    Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial
  11. 1211
    “…BACKGROUND: Clinical trial investigators may need to evaluate treatment effects in a specific subgroup (or subgroups) of participants in addition to reporting results of the entire study population. …”
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    Borrowing information across patient subgroups in clinical trials, with application to a paediatric trial
  12. 1212
    “…RESULTS: We identified 1,312 trials registered at ClinicalTrials.gov. Among clinicalTrials.gov registered childhood obesity-related intervention trials, trial unreported results were 88.5 and 4.3% of trials were prematurely terminated. …”
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    Results Reporting and Early Termination of Childhood Obesity Trials Registered on ClinicalTrials.gov
  13. 1213
    “…BACKGROUND: Clinical trial registration has become a valuable tool that can be used to track the status and nature of trials conducted on a specific topic. …”
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    DIet and Health From reGIstered Trials on ClinicalTrials.gov: The DIGIT Study
  14. 1214
    “…BACKGROUND: Clinical trials comprise multiple processes at various stages of the trial lifecycle. …”
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    Behavioural optimisation to address trial conduct challenges: case study in the UK-REBOA trial
  15. 1215
    “…Additionally, acceptance rates on a trial-by-trial basis were altered according to P3 amplitudes in response to the emotional facial reaction of the proposer. …”
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    Neural correlates of successful costly punishment in the Ultimatum game on a trial-by-trial basis
  16. 1216
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    Per‐Protocol Versus Intention‐to‐Treat in Clinical Trials: The Example of GLOBAL‐LEADERS Trial
  17. 1217
    “…IMPORTANCE: Platform trial design allows the introduction of new interventions after the trial is initiated and offers efficiencies to clinical research. …”
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    Economic Evaluation of Cost and Time Required for a Platform Trial vs Conventional Trials
  18. 1218
    “…MATERIALS AND METHODS: This study is a prospective, multicenter, non-randomized controlled trial comparative survey conducted on patients enrolled in a clinical trial to evaluate and improve their understanding after an educational intervention was applied to the research staff. …”
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    Patients’ knowledge about their involvement in clinical trials. A non-randomized controlled trial
  19. 1219
    “…Randomized double-blind placebo-controlled trials (RCTs) are regarded as the gold standard for clinical trials. …”
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    Implications for blinding in clinical trials with THC-containing cannabinoids based on the CANNA-TICS trial
  20. 1220
    “…Data extraction included trial location, participant age, source of the trial record, trial phase, sponsor, and availability of results. …”
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    Rotavirus vaccine clinical trials: a cross-sectional analysis of clinical trials registries
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