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  1. 1481
    por Dal-Ré, Rafael, Caplan, Arthur L.
    Publicado 2021
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    Current COVID-19 vaccine trials in high-income countries: are placebo-controlled trials ethical?
  2. 1482
    “…METHODS AND RESULTS: SORT-AF is an investigator-sponsored, prospective, randomized, multicentre, and clinical trial. Patients with symptomatic AF (paroxysmal or persistent) and body mass index (BMI) 30–40 kg/m(2) underwent AF ablation and were randomized to either weight-reduction (group 1) or usual care (group 2), after sleep–apnoea–screening and loop recorder (ILR) implantation. …”
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    Supervised Obesity Reduction Trial for AF ablation patients: results from the SORT-AF trial
  3. 1483
    “…Inadequate accrual of trial participants is one of the most significant barriers to the completion of oncology clinical trials. …”
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    Trial-level factors affecting accrual and completion of oncology clinical trials: A systematic review
  4. 1484
    “…BACKGROUND: Randomized controlled trials (RCT) play a central role in evidence-based healthcare. …”
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    Generalizability and Transportability of the National Lung Screening Trial Data: Extending Trial Results to Different Populations
  5. 1485
    “…METHODS: MIND-ADmini is a multinational proof-of-concept 6-month randomized controlled trial (RCT), with four trial sites (Sweden, Finland, Germany, France). …”
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    Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress
  6. 1486
    por Bhatt, Arun
    Publicado 2022
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    Clinical trials and Consolidated Standards of Reporting Trials: Continuing concerns of compliance in COVID-19 era
  7. 1487
    Publicado 2021
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    Corrigendum to: The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design
  8. 1488
    “…This study aims to analyze comprehensively therapeutic clinical trials for IgAN registered on ClinicalTrials.gov. …”
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    The comprehensive analysis of clinical trials registration for IgA nephropathy therapy on ClinicalTrials.gov
  9. 1489
    “…However, assessing the effectiveness of resveratrol supplementations as an appropriate intervention for weight loss in obesity across randomized control trials (RCTs) has been complicated by variability in their design. …”
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    Resveratrol for Weight Loss in Obesity: An Assessment of Randomized Control Trial Designs in ClinicalTrials.gov
  10. 1490
    “…Qualitative research can enhance the design, conduct and interpretation of trials. Despite this, few trials incorporate qualitative methods, and those that do may not realise their full potential. …”
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    How to embed qualitative research in trials: insights from the feasibility study of the SAFER trial programme
  11. 1491
    “…METHODS: Survey of primary trial reports, published 2014–2019, identified using an electronic search filter for pragmatic trials implemented in MEDLINE, and registered in ClinicalTrials.gov. …”
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    Informed Consent in Pragmatic Trials: Results from a Survey of Trials published 2014–2019
  12. 1492
    por Le Prell, Colleen G.
    Publicado 2022
    “…Data Collection and Analysis  Comprehensive search and summary of clinical trials listed in the National Library of Medicine ( www.ClinicalTrials.gov ) database identified 61 clinical trials. …”
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    Investigational Medicinal Products for the Inner Ear: Review of Clinical Trial Characteristics in ClinicalTrials.gov
  13. 1493
    “…BACKGROUND: The single patient (n-of-1) trial can be used to resolve therapeutic uncertainty for the individual patient. …”
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    A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes
  14. 1494
    “…The trial had two co-primary outcome measures: International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form and the International Prostate Symptom Score (IPSS). …”
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    Stimulation of the tibial nerve—a randomised trial for urinary problems associated with Parkinson’s—the STARTUP trial
  15. 1495
    “…BACKGROUND: Blinding is an established approach in clinical trials which aims to minimise the risk of performance and detection bias. …”
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    Blinding of study statisticians in clinical trials: a qualitative study in UK clinical trials units
  16. 1496
    “…This randomized controlled trial evaluated the effect of low-frequency intermittent fasting on LDL-C and other biomarkers. …”
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    Randomized controlled trial of once-per-week intermittent fasting for health improvement: the WONDERFUL trial
  17. 1497
    “…The data of this meta-analysis were analyzed using the RevMan v.5.4 software. Additionally, the trial sequential analysis v.0.9.5.10 β was used to estimate the sample size. …”
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    Efficacy of Moxibustion for Primary Osteoporosis: A Trial Sequential Meta-Analysis of Randomized Controlled Trials
  18. 1498
    “…BACKGROUND: The clinical trial landscape has evolved over the last two decades, shaped by advances in therapeutics and drug development and innovation in trial design and methods. …”
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    Update on the clinical trial landscape: analysis of ClinicalTrials.gov registration data, 2000–2020
  19. 1499
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    Prof. Diana R. Elbourne: CONSORT for Cluster Randomized Trials and CONSORT for Noninferiority and Equivalence Trials
  20. 1500
    “…The intervention is low-cost, has the potential to be highly scalable, and could be translatable to other ambulatory HIV clinic settings. TRIAL REGISTRATION: ClinicalTrials.gov: NCT05019495 (August 24, 2021).…”
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    Optimizing tobacco treatment delivery for people with HIV: trial protocol for a randomized controlled trial
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