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Mostrando 121 - 140 Resultados de 2,180 Para Buscar '"The Tudors"', tiempo de consulta: 0.27s Limitar resultados
  1. 121
    “…In this study, we systematically characterized the binding specificity and affinity of the Tudor domains of these three proteins quantitatively. …”
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    Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30
  2. 122
    “…The editing of microRNA (miRNA) precursors, along with Tudor-SN (Snd1) activity, could lead to the elimination of selected miRNAs and reprogram miRNA activity. …”
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    Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos
  3. 123
    “…We applied the complete evaluation chain to the Tudor domain containing protein Spindlin1 and established the in vitro test systems for the double Tudor domain of the histone demethylase JMJD2C. …”
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    Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform
  4. 124
    “…The staphylococcal nuclease and Tudor domain containing 1 gene (SND1), also known as Tudor-SN, TSN or p100, encodes an evolutionarily conserved protein with invariant domain composition. …”
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    Insights Into SND1 Oncogene Promoter Regulation
  5. 125
    “…Here, we provide further evidence that PHF1 co-localizes with H3t in testis and its Tudor domain preferentially binds to H3tK27me3 over canonical H3K27me3 in vitro. …”
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    Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
  6. 126
    “…Here, we show that LOTUS (Limkain, Oskar, and Tudor containing proteins 5 and 7) domains present in the germline proteins Oskar, TDRD5 (Tudor domain-containing 5), and TDRD7 bind and stimulate the germline-specific DEAD-box RNA helicase Vasa. …”
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    The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage
  7. 127
    “…Survival of motor neuron (SMN) functions in diverse biological pathways via recognition of symmetric dimethylarginine (Rme2s) on proteins by its Tudor domain, and deficiency of SMN leads to spinal muscular atrophy. …”
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    A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II
  8. 128
    “…Correction to Tudor-Locke C, Hart TL, Washington TL: Expected values for pedometer-determined physical activity in older populations. …”
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    Correction: Expected values for pedometer-determined physical activity in older populations
  9. 129
    “…Deletion of Tudor domains abolished anti-AMPK and antiviral activities of TDRD7. …”
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    Interferon-stimulated gene TDRD7 interacts with AMPK and inhibits its activation to suppress viral replication and pathogenesis
  10. 130
    “…SIMPLE SUMMARY: Tudor domain-containing proteins (TDRDs) are a group of evolutionarily conserved and germline-enriched proteins, and most of them function in reproduction and the P-element-induced wimpy testis-interacting RNA (piRNA) pathway. …”
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    TDRD5 Is Required for Spermatogenesis and Oogenesis in Locusta migratoria
  11. 131
    “…The Tudor domain-containing proteins are characterized by their specific interactions with methylated protein motifs, including methyl-arginines and methyl-lysines. …”
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    Arginine methylation of USP9X promotes its interaction with TDRD3 and its anti-apoptotic activities in breast cancer cells
  12. 132
    “…These proteins contain a TUDOR domain binding H3K36me3, two PHD domains and a “Winged-helix” domain involved in GC-rich DNA binding. …”
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    hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells
  13. 133
    por Wang, Yalong, Bedford, Mark T.
    Publicado 2023
    “…We will focus on the biological functions of the Tudor domain-containing methylarginine readers and address other domains and complexes that sense methylarginine marks.…”
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    Effectors and effects of arginine methylation
  14. 134
    por Gutierrez-Beltran, Emilio
    Publicado 2015
    “…Recently, we have showed that Tudor Staphylococcal Nuclease (TSN or Tudor-SN) proteins (TSN1 and TSN2) are localized in cytoplasmic messenger ribonucleoprotein (mRNP) complexes called stress granules (SG) and processing bodies (PB) under heat stress in Arabidopsis. …”
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    Genome-wide analysis of uncapped mRNAs under heat stress in Arabidopsis
  15. 135
    “…Papi binds first to Siwi via the Tudor domain and subsequently to piRNA precursors loaded onto Siwi via the K-homology (KH) domains. …”
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    Siwi cooperates with Par-1 kinase to resolve the autoinhibitory effect of Papi for Siwi-piRISC biogenesis
  16. 136
    “…Thus complexes containing Tudor, Aub piRNPs and mRNAs couple piRNA inheritance with germline specification. …”
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    Sequence-dependent but not sequence-specific piRNA adhesion traps mRNAs to the germ plasm
  17. 137
    “…Moreover, RNAi screenings for Bombyx genes encoding TUDOR domain-containing proteins identified BmPAPI, a Bombyx homolog of Drosophila PAPI, as a factor modulating the length of mature piRNAs. …”
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    Mitochondrial protein BmPAPI modulates the length of mature piRNAs
  18. 138
    “…Furthermore, we show that glial granule scaffold protein Tudor functions in silencing of transposable elements and in small regulatory piRNA biogenesis. …”
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    Glial granules contain germline proteins in the Drosophila brain, which regulate brain transcriptome
  19. 139
    “…The staphylococcal nuclease and Tudor domain-containing 1 (SND1) effector protein is a key reader of the marks deposited by PRMT5. …”
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    The Role of the PRMT5–SND1 Axis in Hepatocellular Carcinoma
  20. 140
    por Oprea, Tudor Ionel
    Publicado 2002
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    Virtual Screening in Lead Discovery: A Viewpoint†
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