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  1. 9121
    “…METHODS: Patients with knee OA (n = 80) will undertake a structured exercise program for five consecutive days. …”
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    Additive effect of tDCS combined with Peripheral Electrical Stimulation to an exercise program in pain control in knee osteoarthritis: study protocol for a randomized controlled trial
  2. 9122
    “…The procedure can be simplified and complications minimised by undertaking a ‘supracervical’ hysterectomy where the cervix is left in situ and only the body of the uterus removed. …”
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    HEALTH: laparoscopic supracervical hysterectomy versus second-generation endometrial ablation for the treatment of heavy menstrual bleeding: study protocol for a randomised controlled trial
  3. 9123
    “…It is important, therefore, to undertake this randomized control trial to determine whether DKD is effective or not. …”
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    Efficacy and safety of Ding-Kun-Dan for female infertility patients with predicted poor ovarian response undergoing in vitro fertilization/intracytoplasmic sperm injection: study protocol for a randomized controlled trial
  4. 9124
    “…We firstly needed to test the feasibility and acceptability of this treatment approach and explore how best to evaluate it before undertaking a definitive trial. METHODS: A feasibility study with a cluster randomised controlled trial component was undertaken to 1. …”
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    Chair based exercise in community settings: a cluster randomised feasibility study
  5. 9125
    “…We now seek to determine the effectiveness and cost-effectiveness of ARRISA in reducing asthma-related crisis events. METHODS: We are undertaking a pragmatic, two-arm, multicentre, cluster randomised controlled trial, plus health economic and process evaluation. …”
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    At-risk registers integrated into primary care to stop asthma crises in the UK (ARRISA-UK): study protocol for a pragmatic, cluster randomised trial with nested health economic and process evaluations
  6. 9126
    “…BACKGROUND: Accurate assessment of liver health prior to undertaking resectional liver surgery or chemoembolisation for primary and secondary cancers is essential for patient safety and optimal outcomes. …”
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    Study protocol: HepaT1ca – an observational clinical cohort study to quantify liver health in surgical candidates for liver malignancies
  7. 9127
    “…Fewer than 30% of independently mobile stroke survivors undertake recommended levels of PA. Sedentary behaviour is also high in this population. …”
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    How should long-term free-living physical activity be targeted after stroke? A systematic review and narrative synthesis
  8. 9128
    “…BACKGROUND: In China, antiretroviral therapy (ART) clinics focus on treating people living with HIV and are not required to undertake testing of high-risk populations. To improve partner testing among MSM, we implemented a health communication pilot intervention integrating partner testing with ART services. …”
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    A health communication intervention to integrate partner testing with antiretroviral therapy service among men who have sex with men in China: an observational cohort study
  9. 9129
    “…METHODS AND ANALYSIS: We propose to undertake a multi-centre, double-blind, placebo-controlled, randomised trial (around 70 sites across the UK) and recruit 328 women with tEPs (with pre-treatment serum hCG of 1000–5000 IU/L). …”
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    A multi-centre, double-blind, placebo-controlled, randomised trial of combination methotrexate and gefitinib versus methotrexate alone to treat tubal ectopic pregnancies (GEM3): trial protocol
  10. 9130
    “…Potential core outcomes will be developed by undertaking a systematic review of studies evaluating interventions for selective fetal growth restriction in monochorionic twin pregnancies. …”
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    Study protocol: developing, disseminating, and implementing a core outcome set for selective fetal growth restriction in monochorionic twin pregnancies
  11. 9131
    “…If findings indicate feasibility and acceptability, we will undertake planning for a phase III RCT of effectiveness. …”
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    Protocol for pilot cluster RCT of project respect: a school-based intervention to prevent dating and relationship violence and address health inequalities among young people
  12. 9132
    “…METHODS: This is the protocol paper for the Every Newborn-INDEPTH study (INDEPTH Network, International Network for the Demographic Evaluation of Populations and their Health Every Newborn, Every Newborn Action Plan), aiming to undertake a randomised comparison of FBH(+) and FPH to measure pregnancy outcomes in a household survey in five selected INDEPTH Network sites in Africa and South Asia (Bandim in urban and rural Guinea-Bissau; Dabat in Ethiopia; IgangaMayuge in Uganda; Kintampo in Ghana; Matlab in Bangladesh). …”
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    “Every Newborn-INDEPTH” (EN-INDEPTH) study protocol for a randomised comparison of household survey modules for measuring stillbirths and neonatal deaths in five Health and Demographic Surveillance sites
  13. 9133
    “…Implied in that goal is that viral load be quantified for all patients receiving treatment, which is a challenging undertaking given the complexity and high cost of standard-of-care viral load testing methods. …”
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    The role of point-of-care viral load monitoring in achieving the target of 90% suppression in HIV-infected patients in Nigeria: study protocol for a randomized controlled trial
  14. 9134
    “…Using a multidimensional research protocol, divided in three stages: 1- The identification of the subjects, and the scheduling of tests; 2- Situational diagnosis through interviews, anthropometric evaluation, measuring blood pressure, collecting hair and nail samples to detect exposure to heavy metals and undertaking laboratory tests; 3- The return of the waste pickers to receive the test results, followed by referral to the health team and to report occupational accidents. …”
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    Health conditions and occupational risks in a novel group: waste pickers in the largest open garbage dump in Latin America
  15. 9135
    “…Prior to a large-scale trial, we first need to undertake a pilot and feasibility trial to address current uncertainties about recruitment, retention and barriers to adherence to the interventions, particularly in relation to whether patients will be willing to begin moving their arm early after their operation. …”
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    Protocol for a multi-centre pilot and feasibility randomised controlled trial with a nested qualitative study: rehabilitation following rotator cuff repair (the RaCeR study)
  16. 9136
    “…As equipoise remains, we plan to undertake a fully powered multi-centre trial to test clinical and cost effectiveness of paramedic-administered FICB at the scene of hip fracture. …”
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    Rapid Analgesia for Prehospital hip Disruption (RAPID): findings from a randomised feasibility study
  17. 9137
    “…A trained healthcare professional will lead the following phases at each site: (1) undertake baseline clinical practice audits, (2) form multidisciplinary Implementation Teams, (3) identify target behaviours for practice change, (4) identify barriers to change, (5) generate intervention strategies, (6) support staff to implement interventions and (7) evaluate the effectiveness of the intervention using post-implementation clinical data. …”
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    Comparing theory and non-theory based implementation approaches to improving referral practices in cancer genetics: a cluster randomised trial protocol
  18. 9138
    “…Working closely with local stakeholders, this study will design and undertake feasibility evaluation of co-produced mental health literacy and anxiety and depression focussed interactive self-management tools. …”
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    Improving mental health literacy among young people aged 11–15 years in Java, Indonesia: co-development and feasibility testing of a culturally-appropriate, user-centred resource (IMPeTUs) – a study protocol
  19. 9139
    “…BACKGROUND: Self-management is a critical component of chronic disease management and can include a host of activities, such as adhering to prescribed medications, undertaking daily care activities, managing dietary intake and body weight, and proactively contacting medical practitioners. …”
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    Usefulness of Wearable Cameras as a Tool to Enhance Chronic Disease Self-Management: Scoping Review
  20. 9140
    por Scott, Jan, Hidalgo-Mazzei, Diego, Strawbridge, Rebecca, Young, Allan, Resche-Rigon, Matthieu, Etain, Bruno, Andreassen, Ole A., Bauer, Michael, Bennabi, Djamila, Blamire, Andrew M., Boumezbeur, Fawzi, Brambilla, Paolo, Cattane, Nadia, Cattaneo, Annamaria, Chupin, Marie, Coello, Klara, Cointepas, Yann, Colom, Francesc, Cousins, David A., Dubertret, Caroline, Duchesnay, Edouard, Ferro, Adele, Garcia-Estela, Aitana, Goikolea, Jose, Grigis, Antoine, Haffen, Emmanuel, Høegh, Margrethe C., Jakobsen, Petter, Kalman, Janos L., Kessing, Lars V., Klohn-Saghatolislam, Farah, Lagerberg, Trine V., Landén, Mikael, Lewitzka, Ute, Lutticke, Ashley, Mazer, Nicolas, Mazzelli, Monica, Mora, Cristina, Muller, Thorsten, Mur-Mila, Estanislao, Oedegaard, Ketil Joachim, Oltedal, Leif, Pålsson, Erik, Papadopoulos Orfanos, Dimitri, Papiol, Sergi, Perez-Sola, Victor, Reif, Andreas, Ritter, Philipp, Rossi, Roberto, Schulze, Thomas, Senner, Fanny, Smith, Fiona E., Squarcina, Letizia, Steen, Nils Eiel, Thelwall, Pete E., Varo, Cristina, Vieta, Eduard, Vinberg, Maj, Wessa, Michele, Westlye, Lars T., Bellivier, Frank
    Publicado 2019
    “…STRUCTURE: The H2020-funded Response to Lithium Network (R-LiNK; http://www.r-link.eu.com/) will undertake a prospective cohort study of over 300 individuals with bipolar-I-disorder who have agreed to commence a trial of lithium treatment following a recommendation by their treating clinician. …”
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    Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
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