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  1. 8801
    “…Although a slowing of electroencephalographic (EEG) activity during wakefulness and –to some extent- sleep of Alzheimer disease (AD) patients (i.e., increased slow-frequency activity) was documented, recent findings in healthy elderly show a decreased 0.6–1 Hz slow wave activity (SWA) during NREM, which was associated to β-amyloid deposition and impaired hippocampal memory consolidation. …”
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    The Fall of Sleep K-Complex in Alzheimer Disease
  2. 8802
    “…We term this effect Prolonged Morning Wakefulness (PMW). We show that signalling through the TrpA1 thermo-sensor is required for PMW, and that TrpA1 specifically impacts siesta onset, but not night sleep onset, in response to elevated temperatures. …”
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    Regulation of sleep plasticity by a thermo-sensitive circuit in Drosophila
  3. 8803
    “…The most robust effects were sleep problems at 18 years [adjusted odds ratio (OR) for a 1 s.d. increase in PND, 1.26, 95% confidence interval (CI) 1.15–1.39, p < 0.001] and waking more often (adjusted OR 1.14, 95% CI 1.05–1.25, p = 0.003). …”
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    The association between maternal postnatal depressive symptoms and offspring sleep problems in adolescence
  4. 8804
    “…Temporal patterns of sleep-wakefulness and feeding also changed accordingly. Such results suggest that along with mechanisms in the SCN, local Bmal1–dependent clocks in the ventral forebrain are critical for generating precise temporal patterns of circadian behaviors.…”
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    Fine-Tuning Circadian Rhythms: The Importance of Bmal1 Expression in the Ventral Forebrain
  5. 8805
    “…Each set of exercise comprised 3-min of continuous repetition of climbing briskly to the second floor followed by slow waking down to the first floor in their home. A rest period of 1–2 min was allowed between each set. …”
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    Repeated 3-minute stair climbing-descending exercise after a meal over 2 weeks increases serum 1,5-anhydroglucitol levels in people with type 2 diabetes
  6. 8806
    “…METHODS: We jointly applied the Coma Recovery Scale-Revised, FDG–PET and PCI to assess 24 patients with non-acute disorders of consciousness or locked-in syndrome (13 male; 19–54 years old; 12 traumatic; 9 unresponsive wakefulness syndrome, 11 minimally conscious state; 2 emergence from the minimally conscious state, and 2 locked-in syndrome). …”
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    Measures of metabolism and complexity in the brain of patients with disorders of consciousness
  7. 8807
    “…CONCLUSION: Brain activity could help in discerning whether the status of wakefulness in VS is also accompanied by partial awareness, as occurs in MCS. …”
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    Functional Evaluation of Awareness in Vegetative and Minimally Conscious State
  8. 8808
    “…Glaucoma patients annually spend only a few hours in an eye clinic but spend more than 5000 waking hours engaged in everything else. We propose that patients could self-monitor changes in visual symptoms providing valuable between clinic information; we test the hypothesis that this is feasible using a web-based diary tool. …”
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    Self-Monitoring Symptoms in Glaucoma: A Feasibility Study of a Web-Based Diary Tool
  9. 8809
    “…It is common practice to define NWT as periods >60 minutes of consecutive zero-accelerations, but this algorithm was originally developed for waking hours only and its applicability to 24 h-accelerometry is unclear. …”
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    24 h-accelerometry in epidemiological studies: automated detection of non-wear time in comparison to diary information
  10. 8810
    “…OBJECTIVE: To investigate the relationship between the presence of a circadian body temperature rhythm and behaviorally assessed consciousness levels in patients with disorders of consciousness (DOC; i.e., vegetative state/unresponsive wakefulness syndrome or minimally conscious state). …”
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    Significance of circadian rhythms in severely brain-injured patients: A clue to consciousness?
  11. 8811
    por Gillett, Emily S., Perez, Iris A.
    Publicado 2016
    “…We review respiratory issues that may contribute to sudden death events in PWS patients during sleep and wakefulness. We also discuss therapeutic options for treating sleep disordered breathing including adenotonsillectomy, weight loss, and CPAP. …”
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    Disorders of Sleep and Ventilatory Control in Prader-Willi Syndrome
  12. 8812
    “…The outcome measure, percentage of waking time spent sedentary (sedentary time), was measured using an activPAL activity monitor worn continuously for seven days. …”
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    The Influence of Neighbourhoods and the Social Environment on Sedentary Behaviour in Older Adults in Three Prospective Cohorts
  13. 8813
    “…The orexinergic system of the lateral hypothalamus plays a crucial role in maintaining wakefulness and mediating arousal in a circadian time-dependent manner. …”
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    Multiple excitatory actions of orexins upon thalamo-cortical neurons in dorsal lateral geniculate nucleus - implications for vision modulation by arousal
  14. 8814
    “…Patient tolerance, wakefulness during sedation, and cooperation were similar in both groups. …”
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    Capnography monitoring the hypoventilation during the induction of bronchoscopic sedation: A randomized controlled trial
  15. 8815
    “…RESULTS: On average, participants spent 87% of their waking hours in sedentary behaviour, which accumulated in 52 bouts per day with each bout lasting an average of 13 minutes. …”
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    Association between Sedentary Behaviour and Physical, Cognitive, and Psychosocial Status among Older Adults in Assisted Living
  16. 8816
    “…LC is the main source of forebrain norepinephrine (NE) and it modulates a variety of functions including sleep-waking cycle, alertness, synaptic plasticity, and memory. …”
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    The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer’s Disease
  17. 8817
    “…After an acclimation procedure, we show that fMRI can be successfully performed during wakefulness, enabling the detection of reproducible BOLD responses to sound. …”
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    Auditory evoked BOLD responses in awake compared to lightly anaesthetized zebra finches
  18. 8818
    por Kraehenmann, Rainer
    Publicado 2017
    “…Therefore psychedelic states are closest to lucid dreaming which is characterized by a mixed state of dreaming and waking consciousness CONCLUSION: The broad overlap between dreaming and psychedelic states supports the notion that psychedelics acutely induce dreamlike subjective experiences which may have long-term beneficial effects on psychosocial functioning and well-being. …”
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    Dreams and Psychedelics: Neurophenomenological Comparison and Therapeutic Implications
  19. 8819
    “…At the synaptic level, the average cortical synaptic strength is known to be potentiated during wakefulness and depressed during sleep. Moreover, learning causes plasticity in a subset of synapses, allocating memory to them. …”
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    The Roles of Cortical Slow Waves in Synaptic Plasticity and Memory Consolidation
  20. 8820
    “…Thalamocortical interactions are crucially involved in conscious perception; hence the thalamocortical network might be a promising target for anesthetic modulation of neuronal information pertaining to arousal and waking behavior. General anesthetics affect the neurophysiology of the thalamus and the cortex but the exact mechanisms of how anesthetics interfere with processing thalamocortical information remain to be elucidated. …”
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    Propofol and Sevoflurane Differentially Modulate Cortical Depolarization following Electric Stimulation of the Ventrobasal Thalamus
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