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2761“…These [Image: see text] and [Image: see text] nearest neighbors, with CA adjacent to a closing Watson−Crick pair, are further stabilized when the pH is lowered from 7 to 5.5. …”
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2762por Valdés-Hernández, Pedro Antonio, Sumiyoshi, Akira, Nonaka, Hiroi, Haga, Risa, Aubert-Vásquez, Eduardo, Ogawa, Takeshi, Iturria-Medina, Yasser, Riera, Jorge J., Kawashima, Ryuta“…We also provide a preliminary digitalization of latest Paxinos and Watson atlas for anatomical and functional interpretations within the cerebral cortex. …”
Publicado 2011
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2763“…This limited anticodon repertoire implies that each tRNA anticodon needs to wobble (establish a non-Watson-Crick base pairing between two nucleotides in RNA molecules) to recognize one or more synonymous codons. …”
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2764“…MBD4 specifically recognizes the Watson–Crick polar edge of thymine or 5hmU via the O(2), N(3) and O(4) atoms, thus restricting its activity to thymine/uracil-based modifications while excluding cytosine and its derivatives. …”
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2765por Renken, Felix, Renken, Svenja, Paech, Andreas, Wenzl, Michael, Unger, Andreas, Schulz, Arndt P“…In the minimal invasive arm, the so called “direct anterior approach” (DAA) was chosen, in the conventional arm the Watson-Jones-Approach was used for implantation of a bipolar hemi-arthroplasty. …”
Publicado 2012
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2766por Pettini, Elena, Prota, Gennaro, Ciabattini, Annalisa, Boianelli, Alessandro, Fiorino, Fabio, Pozzi, Gianni, Vicino, Antonio, Medaglini, Donata“…T cells were indeed activated by the antigen encounter and acquired homing molecules essential to disseminate towards distal lymphoid organs as confirmed by the modulation of CD45RB, CD69, CD44 and CD62L marker expression. A multi-type Galton Watson branching process, previously used for in vitro analysis of T-cell proliferation, was applied to model in vivo CFSE proliferation data in draining lymph nodes 57 hours following immunization, in order to calculate the probabilistic decision of a cell to enter in division, rest in quiescence or migrate/die. …”
Publicado 2013
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2767“…Moreover, the energy of the Watson–Crick pairing of complementary single strands to form double-helical structures was calculated. …”
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2768“…The best known factor for target recognition is the so called seed – a short continuous region of Watson-Crick base pairing between nucleotides 2–7 of the miRNA and complementary sequences in 3′ untranslated regions of target mRNAs. …”
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2769por Hashimoto, Hideharu, Pais, June E., Zhang, Xing, Saleh, Lana, Fu, Zheng-Qing, Dai, Nan, Corrêa, Ivan R., Zheng, Yu, Cheng, Xiaodong“…The flipped 5mC is positioned in the active site pocket with planar stacking contacts, Watson–Crick polar hydrogen bonds and van der Waals interactions specific for 5mC. …”
Publicado 2013
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2770por Godar, Amar S., Varanasi, Vijaya K., Nakka, Sridevi, Prasad, P. V. Vara, Thompson, Curtis R., Mithila, J.“…A marked alteration in mesotrione [a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor] efficacy on Palmer amaranth (Amaranthus palmeri S. Watson) was observed when grown under low- (LT, 25/15°C, day/night temperatures) and high (HT, 40/30°C) temperature compared to optimum (OT, 32.5/22.5°C) temperature. …”
Publicado 2015
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2771“…RESULTS: Contacts between the two loops were progressively lost when larger inter-loop distances were enforced. Inter-loop Watson-Crick contacts survived at larger separation when compared with non-canonical pairing and stacking interactions. …”
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2772“…Given that the m6G:U base pair is predicted to be nearly indistinguishable from a Watson-Crick base pair, our data suggest that the decoding center of the ribosome is extremely sensitive to changes at the second position. …”
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2773por Rybarczyk, Agnieszka, Szostak, Natalia, Antczak, Maciej, Zok, Tomasz, Popenda, Mariusz, Adamiak, Ryszard, Blazewicz, Jacek, Szachniuk, Marta“…Computational approaches typically consider only canonical, Watson-Crick and wobble base pairs. Handling of non-canonical interactions, important for a full description of RNA structure, is still very difficult. …”
Publicado 2015
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2774“…The current study employed a longitudinal design with 58 participants aged 17, 18, and 19 years completing social cognition and executive function tasks, Wechsler Abbreviated Scale of Intelligence (Wechsler, 1999), Positive and Negative Affect Schedule (Watson et al., 1988), and Hospital Anxiety and Depression Scale (Zigmond and Snaith, 1983) at Time 1 with follow up testing 12–16 months later. …”
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2775“…Post-transcriptional modifications at the anticodon first (wobble) position of tRNA play critical roles in precise decoding of genetic codes. 5-carboxymethoxyuridine (cmo(5)U) and its methyl ester derivative 5-methoxycarbonylmethoxyuridine (mcmo(5)U) are modified nucleosides found at the anticodon wobble position in several tRNAs from Gram-negative bacteria. cmo(5)U and mcmo(5)U facilitate non-Watson–Crick base pairing with guanosine and pyrimidines at the third positions of codons, thereby expanding decoding capabilities. …”
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2776“…They bind to their mRNA targets by Watson-Crick base pairing and are resistant to degradation by both nucleases and proteases. …”
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2777“…Here we take advantage of a recently developed high-throughput sequencing method (DM-tRNA-seq) to identify and quantify tRNA base methylations located at the Watson-Crick face in HEK293T cells at single base resolution. …”
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2778“…Patients were operated on using a modified Watson-Jones anterolateral approach. All patients underwent clinical and radiological follow-up at 6 weeks, 3, 6, and 12 months, and every year postoperatively. …”
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2779por Miao, Zhichao, Adamiak, Ryszard W., Antczak, Maciej, Batey, Robert T., Becka, Alexander J., Biesiada, Marcin, Boniecki, Michał J., Bujnicki, Janusz M., Chen, Shi-Jie, Cheng, Clarence Yu, Chou, Fang-Chieh, Ferré-D'Amaré, Adrian R., Das, Rhiju, Dawson, Wayne K., Ding, Feng, Dokholyan, Nikolay V., Dunin-Horkawicz, Stanisław, Geniesse, Caleb, Kappel, Kalli, Kladwang, Wipapat, Krokhotin, Andrey, Łach, Grzegorz E., Major, François, Mann, Thomas H., Magnus, Marcin, Pachulska-Wieczorek, Katarzyna, Patel, Dinshaw J., Piccirilli, Joseph A., Popenda, Mariusz, Purzycka, Katarzyna J., Ren, Aiming, Rice, Greggory M., Santalucia, John, Sarzynska, Joanna, Szachniuk, Marta, Tandon, Arpit, Trausch, Jeremiah J., Tian, Siqi, Wang, Jian, Weeks, Kevin M., Williams, Benfeard, Xiao, Yi, Xu, Xiaojun, Zhang, Dong, Zok, Tomasz, Westhof, Eric“…Similar to the previous RNA-Puzzles Round II experiment, the prediction of non-Watson–Crick interactions and the observed high atomic clash scores reveal a notable need for an algorithm of improvement. …”
Publicado 2017
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2780por Gaied, Nouha Ben, Glasser, Nicole, Ramalanjaona, Nick, Beltz, Hervé, Wolff, Philippe, Marquet, Roland, Burger, Alain, Mély, Yves“…The 8vdA-labeled oligonucleotides gave more stable duplexes than the corresponding 2AP-labeled sequences when X = A or T, indicating that 8vdA is less perturbing than 2AP and probably adopts an anti conformation to preserve the Watson–Crick H-bonding. In addition, the quantum yield of 8vdA is significantly higher than 2AP in all tested oligonucleotides in both their single strand and duplex states. …”
Publicado 2005
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