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2781por Persson, Jan, Smedh, Ulrika, Johnsson, Åse, Ohlin, Bo, Sundbom, Magnus, Nilsson, Magnus, Lundell, Lars, Sund, Berit, Johnsson, Erik“…Dysphagia was measured with Watson and Ogilvie scores and with the dysphagia module in the QoL scale (QLQ-OG25). …”
Publicado 2017
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2782“…These applications rely heavily on the predictability of hybridization through Watson–Crick base pairing to allow positioning on a nanometer scale, as well as binding to the target transcripts, but also off-target binding to transcripts with partial homology. …”
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2783“…We also showed that using first-order autocorrelation tests, such as the traditional Durbin-Watson statistic, to detect the autocorrelation due to clustered structure could be misleading as the test may show lack of autocorrelation even though ICC is different from zero. …”
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2784por Jurkutat, Julia, Zajonz, Dirk, Sommer, Gerald, Schleifenbaum, Stefan, Möbius, Robert, Grunert, Ronny, Hammer, Niels, Prietzel, Torsten“…CONCLUSION: The modified, less-invasive, lateral transgluteal approach with capsular repair was accompanied by an 86% reduction in dislocation rates when compared to the conventional technique with capsular resection via the anterolateral Watson-Jones-approach. Capsular repair is possible in about 60% of the revision total hip arthroplasty cases, may be considered as beneficial to avoid dislocation and can therefore be recommended.…”
Publicado 2018
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2785“…The 2‘-deoxyguanosine (G) nucleotide has the potential to provide additional chemical information beyond its Watson-Crick base-pairing capacity. Sequences with four or more runs of three G nucleotides each are potential G-quadruplex forming sequences (PQSs) that can adopt G-quadruplex folds. …”
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2786“…Multiple regression analysis showed no significant interaction between the abutment height and the convergence angle (Durbin-Watson ratio: 2.186). CONCLUSION: Within the limitations of this in vitro study, we suggest that the retrievability of cement-retained implant prostheses with RCS can be maintained by adjusting the abutment height and convergence angle, even when they are permanently cemented together.…”
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2787“…Binding specificity is dictated, in part, by hydrogen bonds between the amino acids at two positions in each PPR motif and the Watson-Crick face of the aligned nucleobase. There is evidence that PPR-RNA interactions can compete with RNA-RNA interactions in vivo, and that this competition underlies some effects of PPR proteins on gene expression. …”
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2788por Frank, Mayu O., Koyama, Takahiko, Rhrissorrakrai, Kahn, Robine, Nicolas, Utro, Filippo, Emde, Anne-Katrin, Chen, Bo-Juen, Arora, Kanika, Shah, Minita, Geiger, Heather, Felice, Vanessa, Dikoglu, Esra, Rahman, Sadia, Fang, Alice, Vacic, Vladimir, Bergmann, Ewa A., Vogel, Julia L. Moore, Reeves, Catherine, Khaira, Depinder, Calabro, Anthony, Kim, Duyang, Lamendola-Essel, Michelle F., Esteves, Cecilia, Agius, Phaedra, Stolte, Christian, Boockvar, John, Demopoulos, Alexis, Placantonakis, Dimitris G., Golfinos, John G., Brennan, Cameron, Bruce, Jeffrey, Lassman, Andrew B., Canoll, Peter, Grommes, Christian, Daras, Mariza, Diamond, Eli, Omuro, Antonio, Pentsova, Elena, Orange, Dana E., Harvey, Stephen J., Posner, Jerome B., Michelini, Vanessa V., Jobanputra, Vaidehi, Zody, Michael C., Kelly, John, Parida, Laxmi, Wrzeszczynski, Kazimierz O., Royyuru, Ajay K., Darnell, Robert B.“…We also compared results of expert manual annotations with those from an automated annotation system, Watson Genomic Analysis (WGA), to assess the reliability and time required to identify potentially relevant pharmacologic interventions. …”
Publicado 2019
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2789por Andrea, Sandri, Bogdan, Florentin Mimor, Alessandro, Ditta, Eliana, Finocchio, Vinicio, Danzi, Pierluigi, Piccoli, Dario, Regis, Bruno, Magnan“…All surgical procedures were performed through an anterolateral Watson-Jones approach with the patient in supine position. …”
Publicado 2019
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2790“…MicroRNAs participate in the regulation of ADME gene expression via imperfect complementary Watson—Crick base pairings with target transcripts. …”
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2791“…The reaction mechanism and kinetic model have been developed using a dual-site Langmuir–Hinshelwood–Hougen–Watson mechanism. The activation energies were 12.3 and 27.6 kcal/mol, correspondingly. …”
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2792“…Disability in fruit farmers was associated with female sex (B=−4.47, p<0.001), smoking (B=−4.00, p=0.026), depression (B=2.83, p<0.001), working hours (B=0.96, p=0.001), injuries of the arms (B=10.78, p<0.001) and shoulders (B=6.75, p<0.001), and numbers of upper extremity MSK diseases (B=2.02, p=0.001), with 26.5% of the variance explained (R(2)=0.265, Durbin-Watson test=1.81, p<0.001). CONCLUSION: Fruit tree farmers remain at risk for MSK diseases of the upper extremities. …”
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2793“…Our study relied on a population-based, cross-sectional analysis of the IBM Watson Health MarketScan insurance claim dataset, which incorporates over 150 million unique patients in the US, and the Swedish national inpatient register, which incorporates more than nine million unique Swedes. …”
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2794por Preininger, Anita M, South, Brett, Heiland, Jeff, Buchold, Adam, Baca, Mya, Wang, Suwei, Nipper, Rex, Kutub, Nawshin, Bohanan, Bryan, Jackson, Gretchen Purcell“…OBJECTIVE: This article describes the system architecture, training, initial use, and performance of Watson Assistant (WA), an artificial intelligence-based conversational agent, accessible within Micromedex(®). …”
Publicado 2020
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2795por Mao, Song, Sekula, Bartosz, Ruszkowski, Milosz, Ranganathan, Srivathsan V, Haruehanroengra, Phensinee, Wu, Ying, Shen, Fusheng, Sheng, Jia“…By contrast, the m(4)(2)C modification disrupts the C:G pair and significantly decreases the duplex stability through a conformational shift of native Watson-Crick pair to a wobble-like pattern with the formation of two hydrogen bonds. …”
Publicado 2020
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2796por Afek, Ariel, Shi, Honglue, Rangadurai, Atul, Sahay, Harshit, Senitzki, Alon, Xhani, Suela, Fang, Mimi, Salinas, Raul, Mielko, Zachery, Pufall, Miles A., Poon, Gregory M.K., Haran, Tali E., Schumacher, Maria A., Al-Hashimi, Hashim M., Gordan, Raluca“…In SaMBA, mismatches are introduced to pre-induce DNA structural distortions much larger than those induced by changes in Watson-Crick sequence. Strikingly, approximately 10% of mismatches increased TF binding, and at least one mismatch was found that increased the binding affinity for each of 22 examined TFs. …”
Publicado 2020
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2797“…DATA SOURCES: We utilized provider data from the American Dental Association, reimbursement data from IBM Watson MarketScan(®) Commercial Research Databases, submitted billed charges from FAIR Health(®), dental insurance market concentration data from FAIR Health(®), and county‐level demographic and economic data from the Area Health Resources File and the Council for Community and Economic Research. …”
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2798por Alvarez, Maria Elena Vilar, Chivers, Martin, Borovska, Ivana, Monger, Steven, Giannoulatou, Eleni, Kralovicova, Jana, Vorechovsky, Igor“…The mutation also reduced flexibility of conserved residues in adjacent exon-derived loops of the central Alu hairpin, revealing a cross-talk between traditional and auxilliary splicing motifs that evolved from opposite termini of 7SL RNA and were approximated by Watson-Crick base-pairing already in organisms without spliceosomal introns. …”
Publicado 2020
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2799“…Here, using reconstituted BER assays in vitro, we report the mutagenic ligation of pol β 8-oxo-2'-deoxyribonucleoside 5'-triphosphate insertion products and an inefficient ligation of pol β Watson–Crick–like dG:T mismatch insertion by the LIG1 mutant with a perturbed fidelity (E346A/E592A). …”
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2800Discovering Collective Variables of Molecular Transitions via Genetic Algorithms and Neural Networks“…The successful retrieval of optimal CVs by this framework is illustrated at the hand of two case studies: the well-known conformational change in the alanine dipeptide molecule and the more intricate transition of a base pair in B-DNA from the classic Watson–Crick pairing to the alternative Hoogsteen pairing. …”
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