Mostrando 1,121 - 1,140 Resultados de 11,266 Para Buscar '"The Watsons"', tiempo de consulta: 0.78s Limitar resultados
  1. 1121
    “…The application of the Smith-Watson-Topper energy-based parameter was revealed to be a good tool for fatigue life prediction of the different series studied.…”
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  2. 1122
    “…N(1)-methyladenine (m(1)A) and N(6)-methyladenine (m(6)A) have been found to be capable of altering DNA structures via disturbing Watson–Crick base pairing. However, little has been known about their influences on non-B DNA structures, which are associated with genetic instabilities. …”
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  3. 1123
    “…A systematic knock-down method using catalytically inactive Cas9 (dCas9) was originally established in bacteria. dCas9 forms a ribonucleoprotein with a small guide RNA and uses it to recognize a specific DNA sequence via Watson-Crick base-pairing. When specifically bound to a targeted DNA, dCas9 impairs RNA polymerase activity and represses transcription of that target gene. …”
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  4. 1124
    “…Major and minor groove DNA contacts in the recognition site involve base-specific hydrogen bonds, van der Waals contacts and the Watson-Crick pairing of a rearranged A:T base pair. …”
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  5. 1125
    “…Current ASO designs strictly follow the rule of Watson-Crick base pairing along target sequences. …”
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  6. 1126
    “…As an alternative strategy to the conventional UBP designs, which involve utility of different recognition modes at the Watson–Crick interface, we now report that the exclusive base pairing can be achieved through the spatial separation of recognition units. …”
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  7. 1127
    “…Both solid and solution results indicated that the K(+)-mediated G-quartet structures were unstable and easily resulted in the breakdown of the hydrogel to form linear ribbon structures by forming mimic reverse Watson–Crick base pairs between the two faces with an intermolecular hydrogen-bond (N10H–O11). …”
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  8. 1128
    “…Furthermore, by NMR spectroscopy, a c(1)G-triggered switch of Watson-Crick into Hoogsteen pairing in HIV-2 TAR RNA was identified. …”
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  9. 1129
    “…An affinity-based process using Watson–Crick interactions was developed that enables purification of DNA-tagged compounds from complex reaction mixtures. …”
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  10. 1130
    “…Moreover, the structure and stability of DNA are influenced by the Watson–Crick pairing and the natural law of DNA creation and conservation, according to which the same mono- or oligonucleotide insertion must be inserted simultaneously into both strands of DNA. …”
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  11. 1131
    “…PredPair learned the Watson-Crick and wobble base-pairing rules and created an internal representation of the stacking energies and helices. …”
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  12. 1132
  13. 1133
  14. 1134
  15. 1135
  16. 1136
  17. 1137
  18. 1138
  19. 1139
  20. 1140
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