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  1. 1801
    por Donny-Clark, Kerry, Broyde, Suse
    Publicado 2009
    “…This facilitates correct incorporation of dT via a Watson−Crick pair. In a 5′-TTTA*GA-3′ sequence the lesion does not form these hydrogen bonds, permitting dA* to rotate around the glycosidic bond to syn and incorporate dT via a Hoogsteen pair. …”
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    Influence of local sequence context on damaged base conformation in human DNA polymerase ι: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion
  2. 1802
    “…X-ray structures of the aptamer moiety of these riboswitches are characterized by a compact fold in which the ligand forms a Watson–Crick base pair with residue 65. Phylogenetic analyses revealed a strict restriction at position 39 of the aptamer that prevents the G39–C65 and A39–U65 combinations, and mutational studies indicate that aptamers with these sequence combinations are impaired for ligand binding. …”
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    Riboswitch structure: an internal residue mimicking the purine ligand
  3. 1803
    “…We found that most mismatches decrease the rate of primer extension by more than 2 orders of magnitude relative to a matched (Watson−Crick) control. A chemical replication system with this property would be able to propagate sequences long enough to have function. …”
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    Effect of Stalling after Mismatches on the Error Catastrophe in Nonenzymatic Nucleic Acid Replication
  4. 1804
    “…Decomposing the pairing free energies into enthalpic and entropic contributions reveals fundamental differences for Watson–Crick pairs compared to pairs involving fluorinated analogs. …”
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    Aromatic N versus aromatic F: bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs
  5. 1805
    “…The Specifier Sequence nucleotides, which pair with the tRNA anticodon, stack with their Watson–Crick edges rotated toward the minor groove and exhibit only modest flexibility. …”
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    NMR structure and dynamics of the Specifier Loop domain from the Bacillus subtilis tyrS T box leader RNA
  6. 1806
    “…Our data however highlight the functional importance of the universally conserved non-Watson-Crick base pair at position A2450–C2063. Modifications that disrupt this base pair markedly impair translation activities, while having little effects on peptide bond formation, tRNA drop-off and ribosome-dependent EF-G GTPase activity. …”
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    The role of the universally conserved A2450–C2063 base pair in the ribosomal peptidyl transferase center
  7. 1807
    “…This model system suggests that disturbed Watson-Crick base pairing is a better recognition signal than a flexible bend, and that these can act in concert to provide an enhanced signal. …”
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    Base Sequence Context Effects on Nucleotide Excision Repair
  8. 1808
    “…Competition assays with nucleotide analogs showed a remarkable convergence of donor recognition requirements, with critical contributions to recognition provided by the Watson–Crick face of the nucleobase, lesser contributions from donor nucleotide ribose hydroxyls, and little or no contribution from the Hoogsteen face. …”
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    Convergent donor and acceptor substrate utilization among kinase ribozymes
  9. 1809
    “…The results indicate that it is possible for the double-stranded DNA to access the RecA-bound ssDNA while initially retaining its Watson–Crick pairing. They emphasize the importance of RecA L2 loop mobility for both recognition and strand exchange.…”
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    Modeling the early stage of DNA sequence recognition within RecA nucleoprotein filaments
  10. 1810
    “…These interactions are optimized in the dehydrated environment that envelops Watson−Crick nascent base pairs and serve to enhance base selectivity in wild-type RB69 pol.…”
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    Insights into Base Selectivity from the 1.8 Å Resolution Structure of an RB69 DNA Polymerase Ternary Complex†
  11. 1811
    “…These inter­actions result in the formation of an infinite ‘double band’ along the b axis that can be considered as a self-assembled analogue of a polynucleotide mol­ecule with non-canonical Watson–Crick base pairs. The infinite chains of 3′-O-acetyl-2′-de­oxy­uridine pairs are additionally held together by C—H⋯O inter­actions involving C atoms of the uracyl base and O atoms of carbonyl groups. …”
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    3′-O-Acetyl-2′-de­oxy­uridine
  12. 1812
    “…The enthalpy-driven, higher stability of the former hints at the possibility that the 2′-substituent, in addition to its important function in sculpting RNA conformation, plays an underappreciated role in modulating Watson–Crick base pairing strength and potentially π–π stacking interactions.…”
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    Unexpected origins of the enhanced pairing affinity of 2′-fluoro-modified RNA
  13. 1813
    “…During recombination, one single-stranded DNA (ssDNA) bound to site I in RecA exchanges Watson–Crick pairing with a sequence-matched ssDNA that was part of a double-stranded DNA molecule (dsDNA) bound to site II in RecA. …”
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    Single-molecule studies of the stringency factors and rates governing the polymerization of RecA on double-stranded DNA
  14. 1814
    “…There are two hydrogen bonds between the Watson–Crick edge of G(anti) and the Hoogsteen edge of G(syn): O6·N1H and N7·N2H. …”
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    Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome
  15. 1815
    “…Viroid genomes fold up on themselves adopting collapsed secondary structures wherein stretches of nucleotides stabilized by Watson–Crick pairs are flanked by apparently unstructured loops. …”
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    Viroids: From Genotype to Phenotype Just Relying on RNA Sequence and Structural Motifs
  16. 1816
    “…We found three mechanisms of compensatory evolution: Watson-Crick interaction (the primary one), complex interactions between multiple sites within a stem, and interplay of stems and loops. …”
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    Coevolution in RNA Molecules Driven by Selective Constraints: Evidence from 5S rRNA
  17. 1817
    “…Polι maintains the adduct in its active site in two distinct conformations. dCTP forms a Watson–Crick base pair with the adducted guanine and excludes the pyrene ring from the helical DNA, which inhibits replication beyond the lesion. …”
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    Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase
  18. 1818
    por Feng, Shu, Chen, Yun, Gao, Yong-Gui
    Publicado 2013
    “…Our results revealed that the Watson-Crick base pairing is formed at the first and second codon-anticodon positions in the E site in the ribosome elongation complex, whereas the codon-anticodon interaction in the third position is indirect. …”
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    Crystal Structure of 70S Ribosome with Both Cognate tRNAs in the E and P Sites Representing an Authentic Elongation Complex
  19. 1819
    “…Contrary to our previously studied wild-type (wt) p53-DNA complexes showing non-canonical Hoogsteen A/T base pairs of the DNA helix that lead to local minor-groove narrowing and enhanced electrostatic interactions with p53, the current structures display Watson–Crick base pairs associated with direct or water-mediated hydrogen bonds with p53 at the minor groove. …”
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    Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein–DNA interactions
  20. 1820
    “…Comparison of the two structures shows that H69 ΨΨΨ has the following unique features: (i) the loop region is closed by a Watson–Crick base pair between Ψ1911 and A1919, which is potentially reinforced by interactions involving Ψ1911N1H and (ii) Ψ modifications at loop residues 1915 and 1917 promote base stacking from Ψ1915 to A1918. …”
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    Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations
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