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18801“…On May 21st 2020, there were 158,488 confirmed cases in England and Wales with 33,081 deaths in SARS-CoV-2 positive patients (1). …”
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18802“…In addition, five controls comprised of synthetic RNA B.1.1.7_601443, B.1.351_678597, P.1_792683, B.1.617.1_1662307 and MN908947.3-Wuhan-hu-1 from Twist bioscience and B.1.1.7 (England/204820464/2020) and B.1.351 (South Africa/KRISP-K005325/2020) from Zeptometrix, NY, USA were used for validation. …”
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18803por Bond, Jessica, Robotham, Dan, Kenny, Alexandra, Pinfold, Vanessa, Kabir, Thomas, Andleeb, Humma, Larkin, Michael, Martin, Jennifer L, Brown, Susan, Bergin, Aislinn D, Petit, Ariane, Rosebrock, Laina, Lambe, Sinéad, Freeman, Daniel, Waite, Felicity“…Participants will be recruited from the five trial centers based in National Health Service mental health trusts across England. Interviews will be conducted by two researchers. …”
Publicado 2021
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18804por Ingram, Jenny, Johnson, Debbie, O’Mahen, Heather A., Law, Roslyn, Culpin, Iryna, Kessler, David, Beasant, Lucy, Evans, Jonathan“…Low-intensity perinatal-specific talking therapies delivered by psychological wellbeing practitioners in routine NHS primary care services in England are acceptable to pregnant women with mild-moderate depression. …”
Publicado 2021
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18805“…This study is based on Norfolk County Council, a local authority in the east of England. We aimed to apply a systems perspective to develop a better understanding of the structures, systems and processes that support a local authority in becoming research-active, identifying gaps in understanding and recommendations for action to address them. …”
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18806por Petermann-Rocha, Fanny, Lyall, Donald M., Gray, Stuart R., Gill, Jason M. R., Sattar, Naveed, Welsh, Paul, Quinn, Terence J., Stewart, William, Pell, Jill P., Ho, Frederick K., Celis-Morales, Carlos“…Incidence follow-up was carried out until the end of March 2021in England and Scotland and the end of March 2018 in Wales. …”
Publicado 2021
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18807por Clemente, Adriana Sarmiento, Kaplan, Sheldon L, Barson, William J, Lin, Philana L, Romero, Jose R, Bradley, John S, Tan, Tina Q, Pannaraj, Pia S, Givner, Larry, Hulten, Kristina G“…A surveillance analysis from England and Taiwan showed a decline in invasive pneumococcal disease (IPD) (Clin Infect Dis. 2021;72: e65-75 and J Infect. 2021;82:296-297). …”
Publicado 2021
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18808por Alvarado, Natasha, McVey, Lynn, Elshehaly, Mai, Greenhalgh, Joanne, Dowding, Dawn, Ruddle, Roy, Gale, Chris P, Mamas, Mamas, Doherty, Patrick, West, Robert, Feltbower, Richard, Randell, Rebecca“…METHODS: QualDash was co-designed with data users and installed in 8 clinical services (3 pediatric intensive care units and 5 cardiology services) across 5 health care organizations (sites A-E) in England between July and December 2019. Champions were identified to support adoption. …”
Publicado 2021
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18809“…Old-old patients also had greater disability, as measured by the Schwab and England scale (p<0.0001) and had greater milestone frequency specifically for dementia (p<0.0001), wheelchair placement (p<0.0001), nursing home placement (p = 0.019), and hospitalisation in the past 1 year (p = 0.05). …”
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18810por Barnes, Courtney, Yoong, Sze Lin, Nathan, Nicole, Wolfenden, Luke, Wedesweiler, Taya, Kerr, Jayde, Ward, Dianne S, Grady, Alice“…METHODS: A 6-month pilot implementation trial using a cluster-randomized controlled trial design was conducted in 22 ECEC centers within the Hunter New England region of New South Wales, Australia. Potentially eligible centers were distributed a recruitment package and telephoned by the research team to assess eligibility and obtain consent. …”
Publicado 2021
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18811por Aktaa, S, Yadegarfar, M E, Wu, J, Rashid, M, De Belder, M, Deanfield, J, Schiele, F, Minchin, M, Mamas, M A, Gale, C P“…METHODS: Cohort study of linked data from the AMI and percutaneous coronary intervention (PCI) registries in England and Wales with outcome data from the Civil Registration of Deaths Register between 2017 and 2020 (representing 236 743 patients from 186 hospitals). …”
Publicado 2021
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18812por Kongnakorn, Thitima, Sarri, Grammati, Freitag, Andreas, Marczell, Kinga, Kazmierska, Paulina, Masters, Elizabeth, Pawar, Vivek, Zhang, Xinke“…We searched MEDLINE, Embase, EconLit (January 2009–January 2020), and select conferences (since 2016) for CEAs of 1L IO treatments in patients with recurrent or metastatic, epidermal growth factor receptor (EGFR)/anaplastic lymphoma kinase (ALK) mutation-negative NSCLC, published in English. TAs from England, Scotland, Canada, Australia, Germany, and France were also examined. …”
Publicado 2021
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18813por Reardon, Tessa, Dodd, Helen, Hill, Claire, Jasper, Bec, Lawrence, Peter J., Morgan, Fran, Rapee, Ronald M., Ukoumunne, Obioha C., Violato, Mara, Davey, Emily, Halliday, Gemma, Jones, Benjamin, Martineau, Lindsey, McCall, Amy, Niekamp, Natascha, Placzek, Anna, Potts, Ruth, Weisser, Tamatha, Creswell, Cathy“…The study will recruit and randomise at least 60 primary/infant schools in England, and on the basis of recruiting 60 schools, we will recruit 1080 trial participants (540 per arm). …”
Publicado 2022
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18814“…In addition, five controls comprised of synthetic RNA B.1.1.7_601443, B.1.351_678597, B.1.351_678597, P.1_792683, B.1.617.1_1662307 and MN908947.3-Wuhan-hu-1 from Twist bioscience and B.1.1.7 (England/204820464/2020) and B.1.351 (South Africa/KRISP-K005325/2020) from (Zeptometrix, NY, USA) were used for validation. …”
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18815por Hanlon, Peter, Jani, Bhautesh D., Nicholl, Barbara, Lewsey, Jim, McAllister, David A., Mair, Frances S.“…METHODS AND FINDINGS: These are observational analyses of cohorts identified from linked routine healthcare data from UK Biobank participants (n = 211,597 from England, Scotland, and Wales with linked primary care data, age 40 to 70, mean age 56.5 years, 54.6% women, baseline assessment 2006 to 2010) and from the Secure Anonymised Information Linkage (SAIL) databank (n = 852,055 from Wales, age 40 to 70, mean age 54.2, 50.0% women, baseline January 2011). …”
Publicado 2022
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18816por Farmer, Andrew, Jones, Louise, Newhouse, Nikki, Kenning, Cassandra, Williams, Nicola, Chi, Yuan, Bartlett, Y Kiera, Plumpton, Catrin, McSharry, Jenny, Cholerton, Rachel, Holmes, Emily, Robinson, Stephanie, Allen, Julie, Gudgin, Bernard, Velardo, Carmelo, Rutter, Heather, Horne, Rob, Tarassenko, Lionel, Williams, Veronika, Locock, Louise, Rea, Rustam, Yu, Ly-Mee, Hughes, Dyfrig, Bower, Peter, French, David“…METHODS: The trial will be a 12-month, multicenter, individually randomized controlled trial in primary care and will recruit adults (aged ≥35 years) with type 2 diabetes in England. Consenting participants will be randomized to receive short SMS text messages intended to affect a change in medication adherence 3 to 4 times per week in addition to usual care. …”
Publicado 2022
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18817por Gallier, S., Topham, A., Nightingale, P., Garrick, M., Woolhouse, I., Berry, M. A., Pankhurst, T., Sapey, E., Ball, S.“…Risk factors for VTE are well known and there are validated risk assessment tools to support the use of prophylactic therapies. In England, reporting the percentage of patients with a completed VTE risk assessment is mandated, but this does not include whether that risk assessment resulted in appropriate prescribing. …”
Publicado 2022
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18818por Grimm, Sabine E., Witlox, Willem, Wolff, Robert, Chalker, Annette, Hiligsmann, Mickael, Wijnen, Ben, Ahmadu, Charlotte, Ryder, Steve, Armstrong, Nigel, Duffy, Steven, Syndikus, Isabel, Kleijnen, Jos, Joore, Manuela A.“…The economic analysis suffered from uncertainty because there was no trial evidence on the comparator in the England and Wales National Health Service (NHS), and it was unclear to what extent the trial (MAVORIC) comparator (vorinostat) was comparable to standard care, referred to as established clinical management (ECM) in the NHS. …”
Publicado 2021
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18819por Delgado, João, Masoli, Jane, Hase, Yoshiki, Akinyemi, Rufus, Ballard, Clive, Kalaria, Raj N., Allan, Louise M.“…Prospective cohort of hospital-based stroke survivors in North-East England was followed for up to 12 years. In this study, we included 355 stroke survivors of ≥75 years of age, not demented 3 months post-stroke, who had had annual assessments during follow-up. …”
Publicado 2022
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18820por Gold, Natalie, Sallis, Anna, Saei, Ayoub, Arambepola, Rohan, Watson, Robin, Bowen, Sarah, Franklin, Matija, Chadborn, Tim“…The 2017-9 Quality Premium for primary care in England sets a target for broad-spectrum prescribing, which should be at or below 10% of total antibiotic prescribing. …”
Publicado 2022
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