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18981por Andrews, Nick, Stowe, Julia, Kirsebom, Freja, Toffa, Samuel, Rickeard, Tim, Gallagher, Eileen, Gower, Charlotte, Kall, Meaghan, Groves, Natalie, O’Connell, Anne-Marie, Simons, David, Blomquist, Paula B., Zaidi, Asad, Nash, Sophie, Iwani Binti Abdul Aziz, Nurin, Thelwall, Simon, Dabrera, Gavin, Myers, Richard, Amirthalingam, Gayatri, Gharbia, Saheer, Barrett, Jeffrey C., Elson, Richard, Ladhani, Shamez N., Ferguson, Neil, Zambon, Maria, Campbell, Colin N.J., Brown, Kevin, Hopkins, Susan, Chand, Meera, Ramsay, Mary, Lopez Bernal, Jamie“…METHODS: We used a test-negative case–control design to estimate vaccine effectiveness against symptomatic disease caused by the omicron and delta (B.1.617.2) variants in England. Vaccine effectiveness was calculated after primary immunization with two doses of BNT162b2 (Pfizer–BioNTech), ChAdOx1 nCoV-19 (AstraZeneca), or mRNA-1273 (Moderna) vaccine and after a booster dose of BNT162b2, ChAdOx1 nCoV-19, or mRNA-1273. …”
Publicado 2022
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18982por Delanerolle, Gayathri, Williams, Robert, Stipancic, Ana, Byford, Rachel, Forbes, Anna, Tsang, Ruby S M, Anand, Sneha N, Bradley, Declan, Murphy, Siobhán, Akbari, Ashley, Bedston, Stuart, Lyons, Ronan A, Owen, Rhiannon, Torabi, Fatemeh, Beggs, Jillian, Chuter, Antony, Balharry, Dominique, Joy, Mark, Sheikh, Aziz, Hobbs, F D Richard, de Lusignan, Simon“…However, variation in terminologies present a barrier as England uses the Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT), while the rest of the United Kingdom uses the Read v2 terminology in primary care. …”
Publicado 2022
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18983por Schmidt, Matthieu, Hajage, David, Landoll, Micha, Pequignot, Benjamin, Langouet, Elise, Amalric, Matthieu, Mekontso-Dessap, Armand, Chiscano-Camon, Luis, Surman, Katy, Finnerty, Dylan, Santa-Teresa, Patricia, Arcadipane, Antonio, Millán, Pablo, Roncon-Albuquerque, Roberto, Blandino-Ortiz, Aaron, Blanco-Schweizer, Pablo, Ricart, Pilar, Gimeno-Costa, Ricardo, Albacete, Carlos Luis, Fortuna, Philip, Schellongowski, Peter, Dauwe, Dieter, Winiszewski, Hadrien, Kimmoun, Antoine, Levy, Bruno, Hermans, Greet, Grasselli, Giacomo, Lebreton, Guillaume, Guervilly, Christophe, Martucci, Gennaro, Karagiannidis, Christian, Riera, Jordi, Combes, Alain“…METHODS: This retrospective study included consecutive adult patients with laboratory-confirmed SARS-CoV-2 infection who received ECMO for ARDS in 21 experienced ECMO centres in eight European countries (Austria, Belgium, England, France, Germany, Italy, Portugal, and Spain) between Jan 1, 2020, and Sept 30, 2021. …”
Publicado 2023
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18984por Eyre, David W, Futschik, Matthias, Tunkel, Sarah, Wei, Jia, Cole-Hamilton, Joanna, Saquib, Rida, Germanacos, Nick, Dodgson, Andrew R, Klapper, Paul E, Sudhanva, Malur, Kenny, Chris, Marks, Peter, Blandford, Edward, Hopkins, Susan, Peto, Tim E A, Fowler, Tom“…METHODS: In this diagnostic study, paired LFD and RT-PCR test results were prospectively collected from asymptomatic and symptomatic participants in the UK between Nov 4, 2020, and March 21, 2022, to support the National Health Service (NHS) England's Test and Trace programme. The LFDs evaluated were the Innova SARS-CoV-2 Antigen Rapid Qualitative Test, the Orient Gene Rapid Covid-19 (Antigen) Self-Test, and the Acon Flowflex SARS-CoV-2 Antigen Rapid Test (Self-Testing). …”
Publicado 2023
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18985por Sastry, Rahul A., Chen, Jia-Shu, Shao, Belinda, Weil, Robert J., Chang, Ki-Eun, Maynard, Ken, Syed, Sohail H., Zadnik Sullivan, Patricia L., Camara, Joaquin Q., Niu, Tianyi, Sampath, Prakash, Telfeian, Albert E., Oyelese, Adetokunbo A., Fridley, Jared S., Gokaslan, Ziya L.“…For patients with lumbar stenosis and degenerative spondylolisthesis, 2 landmark prospective randomized clinical trials (RCTs) published in the New England Journal of Medicine in 2016 did not find clear evidence in favor of decompression with fusion over decompression alone in this population. …”
Publicado 2023
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18986por Jacobs, Ian J, Menon, Usha, Ryan, Andy, Gentry-Maharaj, Aleksandra, Burnell, Matthew, Kalsi, Jatinderpal K, Amso, Nazar N, Apostolidou, Sophia, Benjamin, Elizabeth, Cruickshank, Derek, Crump, Danielle N, Davies, Susan K, Dawnay, Anne, Dobbs, Stephen, Fletcher, Gwendolen, Ford, Jeremy, Godfrey, Keith, Gunu, Richard, Habib, Mariam, Hallett, Rachel, Herod, Jonathan, Jenkins, Howard, Karpinskyj, Chloe, Leeson, Simon, Lewis, Sara J, Liston, William R, Lopes, Alberto, Mould, Tim, Murdoch, John, Oram, David, Rabideau, Dustin J, Reynolds, Karina, Scott, Ian, Seif, Mourad W, Sharma, Aarti, Singh, Naveena, Taylor, Julie, Warburton, Fiona, Widschwendter, Martin, Williamson, Karin, Woolas, Robert, Fallowfield, Lesley, McGuire, Alistair J, Campbell, Stuart, Parmar, Mahesh, Skates, Steven J“…METHODS: In this randomised controlled trial, we recruited postmenopausal women aged 50–74 years from 13 centres in National Health Service Trusts in England, Wales, and Northern Ireland. Exclusion criteria were previous bilateral oophorectomy or ovarian malignancy, increased risk of familial ovarian cancer, and active non-ovarian malignancy. …”
Publicado 2016
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18987por Ausman, James I., Liebeskind, David S., Gonzalez, Nestor, Saver, Jeffrey, Martin, Neil, Villablanca, J. Pablo, Vespa, Paul, Duckwiler, Gary, Jahan, Reza, Niu, Tianyi, Salamon, Noriko, Yoo, Bryan, Tateshima, Satoshi, Buitrago Blanco, Manuel M., Starkman, Sidney“…With the exception of the large population studies from Oxford England, the reported studies on the management of PCD in the literature represent small selected subsets of the universe of PC diseases, the information from which is not generalizable to the universe of PCD patients. …”
Publicado 2018
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18988por Lenguerrand, Erik, Whitehouse, Michael R, Beswick, Andrew D, Kunutsor, Setor K, Burston, Ben, Porter, Martyn, Blom, Ashley W“…METHODS: We did a prospective observational cohort study analysing 623 253 primary hip procedures performed between April 1, 2003, and Dec 31, 2013, in England and Wales and recorded the number of procedures revised because of PJI. …”
Publicado 2018
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18989“…METHODS: This retrospective observational study involved all patients undergoing MoMHR from the National Joint Registry (NJR) for England and Wales subsequently revised for any indication between 2008 and 2014. …”
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18990por de Lusignan, Simon, Jones, Nicholas, Dorward, Jienchi, Byford, Rachel, Liyanage, Harshana, Briggs, John, Ferreira, Filipa, Akinyemi, Oluwafunmi, Amirthalingam, Gayatri, Bates, Chris, Lopez Bernal, Jamie, Dabrera, Gavin, Eavis, Alex, Elliot, Alex J, Feher, Michael, Krajenbrink, Else, Hoang, Uy, Howsam, Gary, Leach, Jonathan, Okusi, Cecilia, Nicholson, Brian, Nieri, Philip, Sherlock, Julian, Smith, Gillian, Thomas, Mark, Thomas, Nicholas, Tripathy, Manasa, Victor, William, Williams, John, Wood, Ian, Zambon, Maria, Parry, John, O’Hanlon, Shaun, Joy, Mark, Butler, Chris, Marshall, Martin, Hobbs, FD Richard“…The Surveillance Platform will provide access to data for health protection and promotion work as authorized through agreements between Oxford, the Royal College of General Practitioners, and Public Health England. All studies using the Trials Platform will go through appropriate ethical and other regulatory approval processes. …”
Publicado 2020
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18991por Pallett, Scott J C, Rayment, Michael, Patel, Aatish, Fitzgerald-Smith, Sophia A M, Denny, Sarah J, Charani, Esmita, Mai, Annabelle L, Gilmour, Kimberly C, Hatcher, James, Scott, Christopher, Randell, Paul, Mughal, Nabeela, Jones, Rachael, Moore, Luke S P, Davies, Gary W“…Symptomatic health-care workers with mild to moderate symptoms were eligible to participate 14 days after onset of COVID-19 symptoms, as per the Public Health England (PHE) case definition. Health-care workers were recruited to the asymptomatic cohort if they had not developed PHE-defined COVID-19 symptoms since Dec 1, 2019. …”
Publicado 2020
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18992por Fitzgerald, Rebecca C, di Pietro, Massimiliano, O'Donovan, Maria, Maroni, Roberta, Muldrew, Beth, Debiram-Beecham, Irene, Gehrung, Marcel, Offman, Judith, Tripathi, Monika, Smith, Samuel G, Aigret, Benoit, Walter, Fiona M, Rubin, Greg, Sasieni, Peter“…METHODS: This multicentre, pragmatic, randomised controlled trial was done in 109 socio-demographically diverse general practice clinics in England. Randomisation was done both at the general practice clinic level (cluster randomisation) and at the individual patient level, and the results for each type of randomisation were analysed separately before being combined. …”
Publicado 2020
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18993por Swann, Olivia V, Holden, Karl A, Turtle, Lance, Pollock, Louisa, Fairfield, Cameron J, Drake, Thomas M, Seth, Sohan, Egan, Conor, Hardwick, Hayley E, Halpin, Sophie, Girvan, Michelle, Donohue, Chloe, Pritchard, Mark, Patel, Latifa B, Ladhani, Shamez, Sigfrid, Louise, Sinha, Ian P, Olliaro, Piero L, Nguyen-Van-Tam, Jonathan S, Horby, Peter W, Merson, Laura, Carson, Gail, Dunning, Jake, Openshaw, Peter J M, Baillie, J Kenneth, Harrison, Ewen M, Docherty, Annemarie B, Semple, Malcolm G“…SETTING: 260 hospitals in England, Wales, and Scotland between 17 January and 3 July 2020, with a minimum follow-up time of two weeks (to 17 July 2020). …”
Publicado 2020
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18994por Aktaa, Suleman, Wu, Jianhua, Nadarajah, Ramesh, Rashid, Muhammad, de Belder, Mark, Deanfield, John, Mamas, Mamas A., Gale, Chris P.“…METHODS: Multi-sourced nationwide cohort study of adults (age ≥18 years) admitted to hospital with TE and deaths from TE in England (hospital and community) between 1st February 2018 and 31st July 2020. …”
Publicado 2021
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18995por Li, Linxin, Poon, Michael T C, Samarasekera, Neshika E, Perry, Luke A, Moullaali, Tom J, Rodrigues, Mark A, Loan, James J M, Stephen, Jacqueline, Lerpiniere, Christine, Tuna, Maria A, Gutnikov, Sergei A, Kuker, Wilhelm, Silver, Louise E, Al-Shahi Salman, Rustam, Rothwell, Peter M“…METHODS: We pooled individual patient data from two prospective, population-based inception cohort studies of all patients with an incident firs-in-a-lifetime ICH in Oxfordshire, England (Oxford Vascular Study; April 1, 2002, to Sept 28, 2018) and Lothian, Scotland, UK (Lothian Audit of the Treatment of Cerebral Haemorrhage; June 1, 2010, to May 31, 2013). …”
Publicado 2021
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18996por Cranmer, Holly, Podkonjak, Tanja, Benson, Eugene, Dabora, Jonathon, Jackson, Graham H“…COVID-19 is a pandemic affecting many countries globally.(1) As of 23(rd) July 2020, there have been 297,146 lab-confirmed cases of COVID-19 in the UK and 45,554 people who tested positive for the virus have died.(2) Patients with multiple myeloma (MM) are at a higher risk of contracting the virus and experiencing more severe outcomes.(3-6) The higher risk is driven by a compromised immune system, the use of immunosuppressive agents and patient characteristics aligning with key risk factors - patients with MM are often elderly and have multiple co-morbidities.(7) In light of the COVID-19 outbreak, NHS England and NICE have issued guidance to modify usual care to reduce patient exposure to COVID-19. …”
Publicado 2020
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18997por Raynaud, Marc, Goutaudier, Valentin, Louis, Kevin, Al-Awadhi, Solaf, Dubourg, Quentin, Truchot, Agathe, Brousse, Romain, Saleh, Nouredine, Giarraputo, Alessia, Debiais, Charlotte, Demir, Zeynep, Certain, Anaïs, Tacafred, Francine, Cortes-Garcia, Esteban, Yanes, Safia, Dagobert, Jessy, Naser, Sofia, Robin, Blaise, Bailly, Élodie, Jouven, Xavier, Reese, Peter P., Loupy, Alexandre“…METHODS: We conducted a comprehensive meta-research on studies (original articles, research letters and case reports) published between 01/01/2019 and 01/01/2021 in 10 high-impact medical and infectious disease journals (New England Journal of Medicine, Lancet, Journal of the American Medical Association, Nature Medicine, British Medical Journal, Annals of Internal Medicine, Lancet Global Health, Lancet Public Health, Lancet Infectious Disease and Clinical Infectious Disease). …”
Publicado 2021
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18998por Jain, Arihant, Nayak, Lingaraj, Kulkarni, Uday Prakash, Mehra, Nikita, Yanamandra, Uday, Kayal, Smita, Damodar, Sharat, M John, Joseph, Singh, Suvir, Mehta, Prashant, Munot, Pritesh, Selvarajan, Sushil, Radhakrishnan, Venkatraman, Kapoor, Rajan, Dubashi, Biswajit, Ram S, Bharath, Jain, Hasmukh, PK, Jayachandran, Lakshmanan, Jeyaseelan, Mani, Thenmozhi, Prakash, Om, Thorat, Jayashree, Das, Satyaranjan, George, Biju, Lad, Deepesh, Malhotra, Pankaj“…Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet (London, England)2018; 391(10136): 2236-71.Lee AJX, Purshouse K. …”
Publicado 2021
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18999por McPhail, Sean, Swann, Ruth, Johnson, Shane A, Barclay, Matthew E, Abd Elkader, Hazem, Alvi, Riaz, Barisic, Andriana, Bucher, Oliver, Clark, Gavin R C, Creighton, Nicola, Danckert, Bolette, Denny, Cheryl A, Donnelly, David W, Dowden, Jeff J, Finn, Norah, Fox, Colin R, Fung, Sharon, Gavin, Anna T, Gomez Navas, Elba, Habbous, Steven, Han, Jihee, Huws, Dyfed W, Jackson, Christopher G C A, Jensen, Henry, Kaposhi, Bethany, Kumar, S Eshwar, Little, Alana L, Lu, Shuang, McClure, Carol A, Møller, Bjørn, Musto, Grace, Nilssen, Yngvar, Saint-Jacques, Nathalie, Sarker, Sabuj, te Marvelde, Luc, Thomas, Rebecca S, Thomas, Robert J S, Thomson, Catherine S, Woods, Ryan R, Zhang, Bin, Lyratzopoulos, Georgios“…FUNDING: Canadian Partnership Against Cancer; Cancer Council Victoria; Cancer Institute New South Wales; Cancer Research UK; Danish Cancer Society; National Cancer Registry Ireland; The Cancer Society of New Zealand; National Health Service England; Norwegian Cancer Society; Public Health Agency Northern Ireland, on behalf of the Northern Ireland Cancer Registry; the Scottish Government; Western Australia Department of Health; and Wales Cancer Network.…”
Publicado 2022
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19000“…INTRODUCTION/BACKGROUND: The Rheumatology service provides outpatient assessment and rehabilitative intervention for CYP with inflammatory/non-inflammatory pain conditions across South London and Southeast England. CRPS remains poorly understood condition. …”
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